{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T04:53:47Z","timestamp":1656651227359},"reference-count":0,"publisher":"Maad Rayan Publishing Company","issue":"9","content-domain":{"domain":["www.aimjournal.ir"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"abstract":"<jats:p>Hepatoblastoma (HBL) is the most frequently detected malignant tumor of the liver in childhood. HBLs detected antenatally or up to 3 months after birth are considered congenital HBLs. We report a five-day-old female infant in whom a hepatic mass was detected at 20 weeks\u2019 gestation. At birth (36 weeks), the hepatic mass measured 12x6 cm, and she had respiratory distress. Pulmonary hypertension (PHT) was detected on echocardiographic evaluation. Despite dual medical therapy, her PHT did not improve. Histologically, the biopsy demonstrated a mixed epithelial-mesenchymal HBL with predominance of fetal morphology in the epithelial component. Chemotherapy was initiated on postnatal day 15; however, the baby died of respiratory failure on postnatal day 23. Conclusion: HBL is an embryonal tumor which can develop early in the intrauterine period. Although the mechanism is not known, it may cause PHT which would affect the prognosis negatively.<\/jats:p>","DOI":"10.34172\/aim.2020.73","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T05:38:35Z","timestamp":1600666715000},"page":"621-623","update-policy":"http:\/\/dx.doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Case of Congenital Hepatoblastoma Coexisting with Pulmonary Hypertension"],"prefix":"10.34172","volume":"23","author":[{"given":"Zeynep Canan","family":"\u00d6zdemir","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatrics, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adviye","family":"\u00c7ak\u0131l Sa\u011fl\u0131k","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeter","family":"D\u00fczenli Kar","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatrics, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelin","family":"K\u00f6\u015fger","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Ar\u0131k","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fe Neslihan","family":"Tekin","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zcan","family":"B\u00f6r","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatrics, Faculty of Medicine, Eski\u015fehir Osmangazi University, Eski\u015fehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2020,9,1]]},"container-title":["Archives of Iranian Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.aimjournal.ir\/PDF\/aim-23-621.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.aimjournal.ir\/PDF\/aim-23-621.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T05:38:35Z","timestamp":1600666715000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.aimjournal.ir\/Article\/aim-4262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,9]]}},"URL":"https:\/\/doi.org\/10.34172\/aim.2020.73","relation":{},"ISSN":["1029-2977","1735-3947"],"issn-type":[{"value":"1029-2977","type":"print"},{"value":"1735-3947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,1]]},"assertion":[{"value":"Academy of Medical Sciences of the I.R. Iran","name":"journal_owner","label":"Journal Owner"},{"value":"Academy of Medical Sciences of the I.R. Iran","name":"journal_publisher","label":"Journal Publisher"}]}}