{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:14:42Z","timestamp":1740183282373,"version":"3.37.3"},"reference-count":0,"publisher":"Maad Rayan Publishing Company","issue":"7","content-domain":{"domain":["journalaim.com"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:p>Background: Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD) marked by rectal and colon inflammation, leading to relapsing symptoms. Its prevalence is increasing, particularly in developed nations, impacting patients\u2019 health. While its exact cause remains unclear, genetic and environmental factors are implicated, elevating the risk of colorectal cancer (CRC). Colectomy, though declining, is still performed in select UC cases, necessitating further study. Methods: We analyzed data from the Iranian Registry of Crohn\u2019s and Colitis (IRCC) to examine UC patients undergoing colectomy. We collected demographic and clinical data from 91 patients, focusing on dysplasia. Statistical analyses assessed dysplasia risk factors. Results: Patients with dysplasia were older at diagnosis and surgery compared to those without dysplasia. Age emerged as a significant risk factor for dysplasia in UC patients undergoing colectomy. No significant associations were found between dysplasia and other factors. Conclusion: Age plays a crucial role in dysplasia risk among UC patients undergoing colectomy. Older age at diagnosis and surgery may indicate a higher risk of dysplasia and CRC. Clinicians should consider age when managing UC patients and implementing screening protocols. Further research with larger samples is needed to confirm these findings. <\/jats:p>","DOI":"10.34172\/aim.28887","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T07:13:47Z","timestamp":1721718827000},"page":"350-356","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Causes of Colectomy in Patients with Ulcerative Colitis: Findings from an Iranian National Registry"],"prefix":"10.34172","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6143-4350","authenticated-orcid":true,"given":"Zahra","family":"Momayez Sanat","sequence":"first","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Homayoon","family":"Vahedi","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Malekzadeh","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Kasaeian","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Research Center for Chronic Inflammatory Diseases, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Clinical Research Development Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Negar","family":"Mohammadi Ganjaroudi","sequence":"additional","affiliation":[{"name":"School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza","family":"Sima","sequence":"additional","affiliation":[{"name":"Sasan Alborz Biomedical Research Center, Masoud Gastroenterology and Hepatology Center, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fariborz","family":"Mansour Ghanaei","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Guilan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Ghadir","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology Diseases Research Center, Qom University of Medical Science, Qom, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafez","family":"Tirgar Fakheri","sequence":"additional","affiliation":[{"name":"Gut and Liver Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siavosh","family":"Nasseri Moghaddam","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7592-4599","authenticated-orcid":true,"given":"Sudabeh","family":"Alatab","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anahita","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Anushiravani","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iradj","family":"Maleki","sequence":"additional","affiliation":[{"name":"Gut and Liver Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas","family":"Yazdanbod","sequence":"additional","affiliation":[{"name":"Digestive Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Vossoughinia","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Seyyedmajidi","sequence":"additional","affiliation":[{"name":"Golestan Research Center of Gastroenterology, Golestan University of Medical Science, Gorgan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayed Jalaleddin","family":"Naghshbandi","sequence":"additional","affiliation":[{"name":"Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadieh","family":"Baniasadi","sequence":"additional","affiliation":[{"name":"Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baran","family":"Parhizkar","sequence":"additional","affiliation":[{"name":"Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saied","family":"Matinkhah","sequence":"additional","affiliation":[{"name":"Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahsanam","family":"Gheibi","sequence":"additional","affiliation":[{"name":"Maternal and Childhood Obesity Research center, Urmia University of Medical Sciences, Urmia, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roya-sadat","family":"Hosseini Hemmat Abadi","sequence":"additional","affiliation":[{"name":"Shahid Sadoughi University, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyedmohamad","family":"Valizadeh Toosi","sequence":"additional","affiliation":[{"name":"Gut and Liver Research Center, Non-communicable Diseases Institute, Mazandaran 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Iran","name":"journal_owner","label":"Journal Owner"},{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_publisher","label":"Journal Publisher"},{"value":"2024-02-02","order":1,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}