{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T21:37:52Z","timestamp":1769722672368,"version":"3.49.0"},"reference-count":0,"publisher":"Maad Rayan Publishing Company","content-domain":{"domain":["journalaim.com"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"published-print":{"date-parts":[[2025,1,1]]},"abstract":"<jats:p>In contrast to experimental studies indicating the neuroprotective role of uric acid (UA), recent clinical studies have shown that increased UA is associated with a risk of acute hemorrhagic stroke. However, the association of UA with intraventricular hemorrhage (IVH) has not been adequately evaluated. In this study, we determined the relationship between UA and IVH in patients with intracerebral hemorrhage (ICH). We included 721 patients with ICH who were admitted to a tertiary hospital in South Korea. The patients were stratified into quartiles based on their UA levels. IVH decreased continuously across all quartiles of UA. After adjusting for confounding factors, the odds ratio (OR) for IVH was significantly lower in the fourth quartile compared with that in the first quartile (OR: 0.713; 95% CI: 0.546\u20130.934; P=0.045). In conclusion, UA is independently associated with IVH, suggesting its protective role against IVH in patients with ICH. <\/jats:p>","DOI":"10.34172\/aim.31804","type":"journal-article","created":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T10:13:57Z","timestamp":1735553637000},"page":"40","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Serum Uric Acid Level and Intraventricular Hemorrhage in Patients with Acute Hemorrhagic Stroke: A Retrospective Observational Study"],"prefix":"10.34172","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9977-6444","authenticated-orcid":true,"given":"Su Jin","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5027-0410","authenticated-orcid":true,"given":"Min Wook","family":"So","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunggun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Won","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8012-7364","authenticated-orcid":true,"given":"Doo-Ho","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2025,1,1]]},"container-title":["Archives of Iranian Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journalaim.com\/PDF\/aim-28-40.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journalaim.com\/PDF\/aim-28-40.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T10:13:57Z","timestamp":1735553637000},"score":1,"resource":{"primary":{"URL":"https:\/\/journalaim.com\/Article\/aim-31804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,1]]},"references-count":0,"URL":"https:\/\/doi.org\/10.34172\/aim.31804","relation":{},"ISSN":["1029-2977","1735-3947"],"issn-type":[{"value":"1029-2977","type":"print"},{"value":"1735-3947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,1]]},"assertion":[{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_owner","label":"Journal Owner"},{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_publisher","label":"Journal Publisher"},{"value":"2024-08-01","order":1,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}