{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T18:34:47Z","timestamp":1778697287113,"version":"3.51.4"},"reference-count":0,"publisher":"Maad Rayan Publishing Company","issue":"9","content-domain":{"domain":["journalaim.com"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:p>Background: Ambient air pollution, especially particulate matter (PM\u2081\u2080) and sulfur dioxide (SO\u2082), has been implicated in exacerbating cardiopulmonary diseases. While emergency department visits have been widely studied, the impact of pollution on intensive care unit (ICU) admissions and mortality is less understood. This retrospective observational study aimed to evaluate the association between monthly air pollutant levels and ICU admissions for cardiopulmonary conditions, as well as in-hospital mortality. Methods: We retrospectively analyzed 6,112 ICU admissions in a tertiary hospital from January 2012 to November 2019. Using defined inclusion criteria, 227 pulmonary and 344 cardiovascular ICU admissions were selected. Monthly PM\u2081\u2080 and SO\u2082 levels were obtained from official air monitoring stations. A one-month lag model was applied for cardiovascular admissions. Multivariate models were used to assess associations, and results were reported with 95% confidence intervals (CIs). Results: Higher PM\u2081\u2080 levels were significantly associated with pulmonary ICU admissions (\u03b2=0.017; 95% CI: 0.003\u20130.031; P=0.020) and with cardiovascular admissions using a one-month lag structure (\u03b2=0.018; 95% CI: 0.005\u20130.030; P=0.006). SO\u2082 showed no significant associations. No significant relationship was observed between air pollution and in-hospital mortality. Chronic kidney disease (HR=1.309; 95% CI: 1.031\u20131.663; P=0.027) and higher Simplified Acute Physiology Score (SAPS) scores (HR=1.012; 95% CI: 1.006\u20131.017; P&lt;0.001) were independent mortality predictors. Conclusion: This study indicates that long-term exposure to PM\u2081\u2080 significantly affects ICU hospitalization rates for both pulmonary and cardiac conditions, particularly reflecting delayed effects in cardiovascular admissions, without a corresponding impact on in-hospital mortality. <\/jats:p>","DOI":"10.34172\/aim.34530","type":"journal-article","created":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T11:20:19Z","timestamp":1759058419000},"page":"514-521","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Ambient PM\u2081\u2080 and SO\u2082 Levels on Intensive Care Unit Admissions Due to Cardiopulmonary Diseases in a Tertiary Care Hospital"],"prefix":"10.34172","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1674-2677","authenticated-orcid":true,"given":"Melike","family":"Y\u00fcksel Yavuz","sequence":"first","affiliation":[{"name":"Katip Celebi University, Faculty of Medicine, Pulmonology Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4032-9209","authenticated-orcid":true,"given":"H\u00fcseyin","family":"D\u00f6ngelli","sequence":"additional","affiliation":[{"name":"Buca Seyfi Demirsoy Training and Research Hospital, Internal Medicine Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7444-0912","authenticated-orcid":true,"given":"Mehmet","family":"Yavuz","sequence":"additional","affiliation":[{"name":"Tepecik Training and Research Hospital, Intensive Care Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8493-7663","authenticated-orcid":true,"given":"Adem","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Tepecik Training and Research Hospital, Intensive Care Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9287-7763","authenticated-orcid":true,"given":"Murat","family":"G\u00fcne\u015f","sequence":"additional","affiliation":[{"name":"Tepecik Training and Research Hospital, Intensive Care Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0657-4948","authenticated-orcid":true,"given":"I\u015f\u0131l","family":"K\u00f6se G\u00fcldo\u011fan","sequence":"additional","affiliation":[{"name":"Tepecik Training and Research Hospital, Intensive Care Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9932-9401","authenticated-orcid":true,"given":"Nimet","family":"\u015eeno\u011flu","sequence":"additional","affiliation":[{"name":"Tepecik Training and Research Hospital, Intensive Care Department, Izmir, Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2025,9,1]]},"container-title":["Archives of Iranian Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journalaim.com\/PDF\/aim-28-514.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journalaim.com\/PDF\/aim-28-514.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T11:20:19Z","timestamp":1759058419000},"score":1,"resource":{"primary":{"URL":"https:\/\/journalaim.com\/Article\/aim-34530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,9,1]]},"published-print":{"date-parts":[[2025,9,1]]}},"URL":"https:\/\/doi.org\/10.34172\/aim.34530","relation":{},"ISSN":["1029-2977","1735-3947"],"issn-type":[{"value":"1029-2977","type":"print"},{"value":"1735-3947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,1]]},"assertion":[{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_owner","label":"Journal Owner"},{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_publisher","label":"Journal Publisher"},{"value":"2025-05-15","order":1,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}