{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T09:17:11Z","timestamp":1763630231548,"version":"3.45.0"},"reference-count":0,"publisher":"Maad Rayan Publishing Company","issue":"10","content-domain":{"domain":["journalaim.com"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:p>Background: Necrotizing enterocolitis (NEC) is one of the most life-threatening conditions affecting neonates admitted to the neonatal intensive care unit (NICU). Prematurity and low birth weight are the most widely recognized risk factors. However, NEC can also occur in term neonates. This study investigated the incidence, clinical presentation, and underlying medical conditions associated with NEC in term neonates at a tertiary referral children\u2019s hospital in Tehran, Iran. Methods: A retrospective review was conducted on term neonates diagnosed with NEC from 2020 to 2023. Data were collected on demographics, clinical presentation, laboratory findings, underlying medical conditions, treatment, and outcomes. Results: Of 975 term neonates admitted to the NICU during the study period, 33 were diagnosed with NEC, yielding an incidence of 3.38% (95% CI: 2.33\u20134.72). The mean birth weight was 3.15\u00b10.57 kg, and NEC symptoms appeared at a mean age of 18.3\u00b18.1 days. Abdominal distention was the most common initial symptom (78.8%). A history of herbal medication intake was reported significantly higher compared to non-NEC term neonates (P=0.02). Medical management was sufficient in 87.9% of cases, and no mortality was observed. The median hospital stay was 9 days (IQR: 7\u201313). Conclusion: This study highlights a notable incidence of NEC among term neonates in a tertiary Iranian NICU and identifies herbal medication intake as a potential risk factor. These findings underscore the importance of early recognition and culturally sensitive preventive strategies in term infants, especially in regions where herbal remedies are commonly used.<\/jats:p>","DOI":"10.34172\/aim.34874","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T09:12:36Z","timestamp":1763629956000},"page":"551-556","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Necrotizing Enterocolitis in Term Neonates: A Retrospective Chart Review from Children\u2019s Medical Center, Tehran (2020\u20132023)"],"prefix":"10.34172","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2974-6362","authenticated-orcid":true,"given":"Kayvan","family":"Mirnia","sequence":"first","affiliation":[{"name":"Children\u2019s Medical Center, Pediatric Center of Excellence, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7659-3533","authenticated-orcid":true,"given":"Maryam","family":"Saeedi","sequence":"additional","affiliation":[{"name":"Children\u2019s Medical Center, Pediatric Center of Excellence, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir Ali","family":"Ahrabi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4496-1108","authenticated-orcid":true,"given":"Razieh","family":"Sangsari","sequence":"additional","affiliation":[{"name":"Children\u2019s Medical Center, Pediatric Center of Excellence, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepideh","family":"Poshtdar","sequence":"additional","affiliation":[{"name":"Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul Latif","family":"Panhwer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2025,10,1]]},"container-title":["Archives of Iranian Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journalaim.com\/PDF\/aim-28-551.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journalaim.com\/PDF\/aim-28-551.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T09:12:38Z","timestamp":1763629958000},"score":1,"resource":{"primary":{"URL":"https:\/\/journalaim.com\/Article\/aim-34874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,1]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025,10,1]]},"published-print":{"date-parts":[[2025,10,1]]}},"URL":"https:\/\/doi.org\/10.34172\/aim.34874","relation":{},"ISSN":["1029-2977","1735-3947"],"issn-type":[{"value":"1029-2977","type":"print"},{"value":"1735-3947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,1]]},"assertion":[{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_owner","label":"Journal Owner"},{"value":"Academy of Medical Sciences of I.R. Iran","name":"journal_publisher","label":"Journal Publisher"},{"value":"2025-07-24","order":1,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}