{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T07:04:17Z","timestamp":1784790257324,"version":"3.55.0"},"reference-count":24,"publisher":"Maad Rayan Publishing Company","issue":"2","content-domain":{"domain":["journalaim.com"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:p>Introduction: The 8-item Inflammatory Bowel Disease control Questionnaire-8 (IBDcQ-8) is a patient-reported measure designed to capture the core domains of disease control and quality of life. The aim of this study was to evaluate the validity and reliability of the Persian version of the IBDcQ-8 in the Iranian IBD population. Methods: A standardized forward\u2013backward translation procedure was employed to adapt the questionnaire into Persian. Content validity was evaluated through structured interviews with a panel of 10 evaluators. Construct validity was examined by structured interview and clinical visits of 101 patients. Harvey Bradshaw Index (HBI), partial Mayo score, and IBD Questionnaire (IBDQ) were used as comparator instruments. Patients\u2019 responses were compared with clinical global assessment, Harvey Bradshaw Index (HBI), partial Mayo score, IBDQ score , and laboratory markers using Spearman\u2019s rank correlation. Test\u2013retest reliability was evaluated by calculating the intraclass correlation coefficient (ICC) between the two subsequent interviews. A P-value&lt;0.05 was considered statistically significant. Results: Half of the subjects (n=51 (50.5%)) were female. The mean age was 38 years (SD=14). Sixty-seven patients (66%) had UC. IBDcQ-8 scores showed strong correlations with HBI and IBDQ, and moderate correlations with the partial Mayo score, CRP, and clinical evaluation at the first visit (P-value&lt;0.05). Agreement was excellent for one-day follow-up (ICC=0.82, 95% CI: 0.71\u20130.89, P&lt;0.001), and moderate for two-week follow-up (ICC=0.61, 95% CI: 0.44\u20130.73, P&lt;0.001). Conclusion: The Persian version of the IBDcQ-8 questionnaire demonstrated robust validity and acceptable reliability even when administered by telephone interview, supporting its usefulness for evaluating disease-specific quality of life in patients with IBD and its applicability in future studies.<\/jats:p>","DOI":"10.34172\/aim.36812","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:11:58Z","timestamp":1784787118000},"page":"69-76","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the Validity and Reliability of the Persian Version of IBDcQ-8 Questionnaire"],"prefix":"10.34172","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7385-0764","authenticated-orcid":true,"given":"Setareh","family":"Moallem","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical 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Iran"},{"name":"Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudabeh","family":"Alatab","sequence":"additional","affiliation":[{"name":"Digestive Disease Research Center, Digestive Disease Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Sima","sequence":"additional","affiliation":[{"name":"Sasan Alborz Biomedical Research Center, Masoud Gastroenterology and Hepatology Center, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Ahadi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 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