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Ensuring an adequate supply of a healthy diet through a transformed food system could be a potential strategy to mitigate T2DM in SSA. In plants, starch is the most common storage carbohydrate, and it is the major glucose-releasing carbohydrate in human diets. The rate of starch digestibility varies and is largely due to the proportion of its two polyglucan components, amylose and amylopectin. Although, no medication has been found to effectively treat T2DM, it could be managed through effective postprandial glycemia control. This article reviews the mechanism for slowing down the rate of starch digestion and absorption in the small intestine through direct alteration of amylose and amylopectin in starch crops. 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