{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T11:24:33Z","timestamp":1792409073566,"version":"4.4.0"},"reference-count":19,"publisher":"Maad Rayan Publishing Company","issue":"4","content-domain":{"domain":["jcvtr.tbzmed.ac.ir"],"crossmark-restriction":false},"short-container-title":["J Cardiovasc Thorac Res"],"published-print":{"date-parts":[[2022,12,31]]},"abstract":"<jats:p>Introduction: Our study objects to determine the diagnostic accuracy of two-dimensional speckle tracking echocardiography (2DSTE) in predicting presence and severity of coronary artery disease (CAD). Methods: Patients with stable angina pectoris with normal left ventricular function (&gt;50%) undergoing coronary angiography were enrolled and subjected to speckle tracking echocardiography. Global longitudinal peak systolic strain was measured and correlated to the results of coronary angiography for each patient. Results: Number of male (P=0.001), diabetes (P=0.01) and smoking (P=0.01) patients were significantly higher in the CAD group compared to non-CAD patients. Global longitudinal peak systolic strain (GLPSS) was significantly (P=0.0001) lower in CAD patients in comparison to non- CAD patients. GLPSS showed significantly lower in patients with Syntax score (SS)\u226522 in comparison to SS&lt;22. Cut-off value -19 for GLPSS could be used to predict the presence of significant CAD with 80.6% sensitivity and 76.5% specificity (area under curve (AUC) -0.83, P=0.0001). The mean GLPSS value decreased as the number of diseased coronary vessels increased (P=0.0001). The optimal cut-off value of -16 GLPSS with a sensitivity of 76.7% and specificity of 83.3% [AUC 0.84, P&lt;0.0001] was found significant to predict CAD severity. Multivariate regression of GLPSS and another risk factor for predicting significant CAD, GLPSS showed OR=1.55 (CI-1.36-1.76) P=0.0001 for predicting the presence of CAD. Conclusion: 2DSTE can be used as a non-invasive screening test in predicting presence, extent and severity of significant CAD patients with suspected stable angina pectoris.<\/jats:p>","DOI":"10.34172\/jcvtr.2022.30520","type":"journal-article","created":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T13:13:26Z","timestamp":1673183606000},"page":"234-239","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The correlation between speckle-tracking echocardiography and coronary angiography in suspected coronary artery disease with normal left ventricular function"],"prefix":"10.34172","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2934-8054","authenticated-orcid":true,"given":"Krishan","family":"Yadav","sequence":"first","affiliation":[{"name":"Yatharth Super Speciality Hospital, Noida, UP, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6387-6822","authenticated-orcid":true,"given":"Jayesh","family":"Prajapati","sequence":"additional","affiliation":[{"name":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8841-5141","authenticated-orcid":true,"given":"Iva","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Research U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Karre","sequence":"additional","affiliation":[{"name":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep Kumar","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicky","family":"Garhwal","sequence":"additional","affiliation":[{"name":"Department of Cardiology, U. N. 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