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The purpose of this article is to report a case of MRONJ treatment associated with aPDT. Case Report: A 75-year-old patient, with a history of breast cancer and use of intravenous Zoledronic Acid, presented with bilateral MRONJ lesions in tuberosity on the right and left sides. Treatment was conservatively instituted with the use of aPDT as an adjuvant. After 12 aPDT sessions, complete regression of the lesion was observed. However, after two weeks, the presence of a new lesion was noted, this time in the anterior region of the maxilla. The same protocol previously established was followed and after two aPDT sessions, the patient returned with complete lesion regression. Conclusion: The use of aPDT may represent an important adjuvant within a set of clinical protocols in the treatment of MRONJ.<\/jats:p>","DOI":"10.34172\/jlms.2021.12","type":"journal-article","created":{"date-parts":[[2021,3,28]],"date-time":"2021-03-28T09:49:22Z","timestamp":1616924962000},"page":"e12-e12","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Photodynamic Therapy as an adjunct in the Treatment of Medication-Related Osteonecrosis of the Jaw: A Case Report"],"prefix":"10.34172","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8521-423X","authenticated-orcid":true,"given":"Marcelo Vieira da Costa","family":"Almeida","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, Real Hospital Portugu\u00eas de Benefic\u00eancia em Pernambuco, 4760 - Paissandu, 52010-075, Recife - PE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9336-7797","authenticated-orcid":true,"given":"Antonio C.","family":"Moura","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Real Hospital Portugu\u00eas de Benefic\u00eancia em Pernambuco, 4760 - 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