{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T02:55:32Z","timestamp":1774752932055,"version":"3.50.1"},"reference-count":29,"publisher":"Maad Rayan Publishing Company","content-domain":{"domain":["journals.sbmu.ac.ir"],"crossmark-restriction":false},"short-container-title":["J Lasers Med Sci"],"published-print":{"date-parts":[[2022,10,25]]},"abstract":"<jats:p>Introduction: Hirsutism, mainly due to polycystic ovary syndrome (PCOS), causes stress, anxiety, and depression in females. Laser-assisted hair removal (LAHR) is currently accepted as a good treatment option for hirsutism. The goal of the current study was to ascertain how LAHR affected the degree of hirsutism, quality of life, and depression in hirsute females.Methods: A single-arm before\/after clinical trial was designed and performed in the Razi hospital Laser Clinic over a 15-month period. All hirsute females visiting the Razi hospital laser clinic were enrolled and received three sessions of LAHR every 4-6 weeks if they were interested and signed an informed consent form. Before the commencement of LAHR and six to eight weeks after the last session, the Ferriman-Gallwey score (hirsutism severity), Beck score (depression index) and DLQI score (quality of life index) were calculated and stored. Results: There were 80 subjects in all. The mean\u2003\u00b1\u2003SD of the Ferriman-Gallwey score was reduced from 7.05\u2003\u00b1\u20032.27 to 4.91\u2003\u00b1\u20032.41, P\u2003&lt;\u20030.001. The mean\u2003\u00b1\u2003SD of the Beck depression score was reduced from 13.3\u2003\u00b1\u20038.7 to 10.2\u2003\u00b1\u20038.4, P\u2003&lt;\u20030.001, and the mean\u2003\u00b1\u2003SD of the DLQI score decreased from 5.6\u2003\u00b1\u20035.2 to 3.5\u2003\u00b1\u20032.3, P\u2003&lt;\u20030.001. No significant complications were reported. Conclusion: LAHR can improve hirsutism-related depression and degradation of quality of life, as well as hirsutism physical signs.<\/jats:p>","DOI":"10.34172\/jlms.2022.46","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T10:52:44Z","timestamp":1674730364000},"page":"e46","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of Laser-Assisted Hair Removal (LAHR) on the Quality of Life and Depression in Hirsute Females: A Single-Arm Clinical Trial"],"prefix":"10.34172","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8863-1269","authenticated-orcid":true,"given":"Mahboubeh Sadat","family":"Hosseini","sequence":"first","affiliation":[{"name":"School of Medicine, Military Health Research Center, Life Style Institute, Baghiyyatollah al-Azam Hospital, Baqiyatallah University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5483-1163","authenticated-orcid":true,"given":"Amir Houshang","family":"Ehsani","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8826-8762","authenticated-orcid":true,"given":"Yousef","family":"Fakour","sequence":"additional","affiliation":[{"name":"Vice Chancellery for Research & Technology, Iran Ministry of Health and Medical Education, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7077-1458","authenticated-orcid":true,"given":"Zeinab","family":"Aryanian","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojtaba","family":"Elhamfar","sequence":"additional","affiliation":[{"name":"Medical Student, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2503-2968","authenticated-orcid":true,"given":"Pedram","family":"Noormohammadpour","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2022,10,25]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.60342"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.1983.53.3.827"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(93)90056-l"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.3109\/0167482x.2010.501398"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2006.01.016"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.69.809.186"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/s0029-7844(02)02725-4"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.83.6.4990"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2003.10.018"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2002.01071.x"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2017.1376099"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.2147\/ijwh.s137910"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.3109\/14764170903449802"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1159\/000066239"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1002\/da.20070"},{"key":"R16","first-page":"143","article-title":"Quality of life indices","volume":"70","author":"Finlay AY","year":"2004","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08832.x"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-4-8"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-21-11-1440"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.12.008"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.10.1323"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2005.01327.x"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12775"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06426.x"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnur.2018.04.008"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.2174\/1381612822666160720151243"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21155342"},{"key":"R28","doi-asserted-by":"crossref","unstructured":"Kolhe JV, Chhipa AS, Butani S, Chavda V, Patel SS. 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