{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:46:28Z","timestamp":1790142388114,"version":"4.0.1"},"reference-count":30,"publisher":"Maad Rayan Publishing Company","content-domain":{"domain":["journals.sbmu.ac.ir"],"crossmark-restriction":false},"short-container-title":["J Lasers Med Sci"],"published-print":{"date-parts":[[2023,1,1]]},"abstract":"<jats:p>Introduction: Dentures, occlusal splints, surgical guides and orthodontic appliances are examples of acrylic resin devices made in dental laboratories, which must be disinfected and even sterilized before insertion into the oral cavity. This study evaluated the antimicrobial effect of photodynamic therapy (PDT) applied to acrylic resin specimens received from different laboratories. Methods: Three hundred standardized specimens were ordered from six randomly selected laboratories registered in the Council of Dentistry of Cear\u00e1 (n=50). The PDT consisted in the association of 22 \u00b5M erythrosine, as a photosensitizer (P), and a 520-nm LED at 38 J\/cm2 (L). The specimens of each laboratory were randomly distributed into five groups: positive control, sterilized with ethylene oxide; negative control, untreated (P-L-); erythrosine control, only stained (P+L-); LED control, only irradiated (P-L+); PDT (P+L+). Then, the specimens were individually sonicated in saline solution; the suspension was diluted, plated on culture mediums (blood agar, sabouraud dextrose agar and a non-selective chromogenic agar), and incubated for 48 hours at 37\u00b0C. Colony-forming-unit (CFU) counts were done and statistical tests of Kruskal-Wallis\/Dunn were carried out. Results: The specimens from all laboratories were contaminated with bacteria and yeasts. Staphylococcus aureus, Staphylococcus saprophyticus, Escherichia coli, Enterococcus spp., Klebsiella and Pseudomonas spp. were identified. The PDT significantly reduced CFU counts (P&lt;0.0001), compared to P-L-. Conclusion: PDT was able to effectively decontaminate the acrylic resin specimens provided from dental laboratories.<\/jats:p>","DOI":"10.34172\/jlms.2023.08","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T07:14:25Z","timestamp":1681888465000},"page":"e8","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Antimicrobial Photodynamic Therapy as a Technique for Decontamination of Acrylic Resin Devices Provided by Different Dental Laboratories"],"prefix":"10.34172","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6468-0477","authenticated-orcid":true,"given":"Bruna Marjorie Dias Frota","family":"de Carvalho","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Christus University Center (UNICHRISTUS), Jo\u00e3o Adolfo Gurgel Street, 133 \u2013 Coc\u00f3, 60190-060, Fortaleza, CE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2217-0986","authenticated-orcid":true,"given":"Bruna Albuquerque","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Oral Biology, University of Florida (College of Dentistry), 1395 Center Drive, POBOX 100424 - 62610, Gainesville, FL, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5445-3190","authenticated-orcid":true,"given":"Aghata Kelma Palacio","family":"Gomes","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Cear\u00e1 Federal University (UFC), Monsenhor Furtado Street \u2013 Rodolfo Te\u00f3filo, 60430-350, Fortaleza, CE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1992-4732","authenticated-orcid":true,"given":"Danielle Dourado","family":"Alcantara","sequence":"additional","affiliation":[{"name":"Dentistry and Nursing, Cear\u00e1 Federal University (UFC), Monsenhor Furtado Street - Rodolfo Te\u00f3filo, 60430-350, Fortaleza, CE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7071-5886","authenticated-orcid":true,"given":"Karina Matthes","family":"de Freitas Pontes","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Cear\u00e1 Federal University (UFC), Monsenhor Furtado Street \u2013 Rodolfo Te\u00f3filo, 60430-350, Fortaleza, CE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"20123","published-online":{"date-parts":[[2023,3,14]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s156815"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-019-00352-9"},{"key":"R3","unstructured":"Dovigo LN. Efetividade da terapia fotodin\u00e2mica na inativa\u00e7\u00e3o de Candida spp [dissertation]. 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