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The search strategy employed the following Medical Subject Headings (MeSH) terms and keywords: (\"Prostatic Neoplasms\" [MeSH] OR \"prostate cancer\") AND (\"Laser Therapy\" [MeSH] OR \"laser ablation\" OR \"focal therapy\"). The search was limited to studies published between 2000 and 2024. Results: The initial search retrieved 1,444 articles. After a rigorous screening of titles, abstracts, and full-texts, 79 studies met the inclusion criteria and were incorporated into the review. The selected literature enables a comprehensive and critical evaluation of the current state of research on focal laser therapy in the management of prostate cancer. Conclusion: While focal laser therapies offer promising outcomes with fewer side effects, their long-term efficacy and survival benefits remain uncertain. High-quality studies with long-term follow-up are essential to better define their role in the prostate cancer treatment landscape and inform optimal patient selection.<\/jats:p>","DOI":"10.34172\/jlms.2025.16","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:19:37Z","timestamp":1764238777000},"page":"e16","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prostate Cancer and the Rise of Focal Laser Therapies: A Narrative Review of Benefits and Limitations"],"prefix":"10.34172","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2071-5321","authenticated-orcid":true,"given":"Alvand","family":"Naserghandi","sequence":"first","affiliation":[{"name":"Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir 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