{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:14:07Z","timestamp":1770880447751,"version":"3.50.1"},"reference-count":38,"publisher":"Maad Rayan Publishing Company","content-domain":{"domain":["journals.sbmu.ac.ir"],"crossmark-restriction":false},"short-container-title":["J Lasers Med Sci"],"published-print":{"date-parts":[[2025,12,6]]},"abstract":"<jats:p>Introduction: This study aimed to assess the effects of supplemental conditioning methods, including extended etching time, Er,Cr:YSGG laser radiation, and sandblasting, on enhancing the recovery of white spot lesions (WSLs) through resin infiltration. Methods: Seventy premolars were subjected to a cariogenic solution to induce WSLs. Subsequently, the teeth were divided into 5 groups of 14, based on the enamel conditioning protocol applied, as follows: Group 1: Icon-Etch (Control), Group 2: Double Icon-Etch, Group 3: Sandblasting+Icon-Etch, Group 4: Er,Cr:YSGG laser+Icon-Etch, and Group 5: Icon-Etch+Er,Cr:YSGG laser+Icon-Etch. The Er,Cr:YSGG laser (2780 nm) was applied at 0.75 W and 20 Hz. Tooth color was measured initially (T0), after WSL induction (T1), and following resin infiltration (T2). Color changes between treatment stages were compared among the groups. Results: One-way analysis of variance (ANOVA) displayed no significant differences in \u0394ET0-T1 or \u0394ET1-T2 between the groups (P&gt;0.05). However, a significant difference was found between the groups in the color change from baseline to post-resin infiltration (\u0394ET0-T2) (P=0.004). The \u0394ET0-T2 was significantly lower in groups 4 and 5 compared to the control group and group 3. Group 2 did not demonstrate a significant difference from the other groups (P&gt;0.05). Conclusion: The combination of laser etching and acid etching was effective in enhancing the recovery of WSLs through resin infiltration. The \u0394ET0-T2 in groups subjected to laser plus acid etching fell below the critical threshold of 3.7 units, indicating that the post-treatment tooth color was not clinically distinguishable from the original tooth color.<\/jats:p>","DOI":"10.34172\/jlms.2025.60","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T06:40:21Z","timestamp":1770878421000},"page":"e60","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Efficacy of Various Conditioning Methods in Restoring the Color of White Spot Lesions Through Resin Infiltration"],"prefix":"10.34172","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7943-6306","authenticated-orcid":true,"given":"Alireza","family":"Boruziniat","sequence":"first","affiliation":[{"name":"Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, 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