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Results: A 30-year-old female patient presented with a nodular, erythematous, pedunculated lesion with firm consistency and an ulcerated surface, measuring approximately 2 cm. Initial evaluation revealed severe anemia (hemoglobin level of 6 g\/dL) caused by a uterine fibroid. After partial improvement of the anemia, an excisional biopsy of the lesion was performed using a high-power diode laser, which provided effective hemostasis during surgery and no postoperative complications. Histopathological examination of the excised tissue confirmed the diagnosis of PG. Conclusion: This case highlights the efficacy and safety of high-power diode lasers in managing oral lesions, especially in the management of systemic conditions such as anemia. The laser\u2019s ability to ensure precise excision and effective hemostasis demonstrates its potential as an indispensable tool in modern minimally invasive surgical approaches, particularly in aesthetic and medically complex cases.<\/jats:p>","DOI":"10.34172\/jlms.2025.62","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T06:41:51Z","timestamp":1770878511000},"page":"e62","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Diode Laser Management of a Lip Pyogenic Granuloma in a Patient With Anemia"],"prefix":"10.34172","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0374-2175","authenticated-orcid":true,"given":"Maria Fernanda da Silva","family":"Nascimento","sequence":"first","affiliation":[{"name":"Christus University Center, Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Santos da","family":"Costa","sequence":"additional","affiliation":[{"name":"School of Dentistry, Christus University Center - Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Emanuel Sousa de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Christus University Center, Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Clara Mendes","family":"Gomes","sequence":"additional","affiliation":[{"name":"School of Dentistry, Christus University Center - Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2313-3386","authenticated-orcid":true,"given":"Juliana Ximenes","family":"Damasceno","sequence":"additional","affiliation":[{"name":"Christus University Center, Unichristus, Fortaleza, Brazil"},{"name":"School of Dentistry, Christus University Center - Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina Rodrigues","family":"Te\u00f3filo","sequence":"additional","affiliation":[{"name":"School of Dentistry, Christus University Center - Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Elisa Quezado Lima","family":"Verde","sequence":"additional","affiliation":[{"name":"Christus University Center, Unichristus, Fortaleza, Brazil"},{"name":"School of Dentistry, Christus University Center - Unichristus, Fortaleza, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2025,12,6]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242316885"},{"key":"R2","unstructured":"Coran AG, Adzick NS, Krummel TM, Laberge JM, Shamberger R, Caldamone A. 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