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Serum and salivary glucose levels were estimated by glucose oxidase\/peroxidase method, serum and salivary IgA by a diagnostic kit, and candidal colonization by inoculating samples into Sabouraud dextrose agar plate. Statistical analyses were carried out by one-way ANOVA, post hoc Tukey tests, and Pearson\u2019s correlation coefficient. Results. Significant elevation of serum IgA levels was observed in group 2 compared to group 3 and significant decreases in salivary IgA levels in groups 1 and 2. The candidal carriage was significantly higher in group 2 compared to group 3. Serum glucose and salivary IgA levels showed a significant correlation in group 1. There was a positive correlation between serum\/ salivary glucose and serum\/salivary IgA levels in group 2. In addition, there was a significant correlation between serum glucose and serum IgA levels in group 3. Conclusion. Saliva could be a potential, non-invasive diagnostic tool to estimate glucose levels. The evaluation of salivary components, like IgA, might be useful in diagnosing and managing oral manifestations in diabetic individuals. Elevated salivary glucose levels contribute to elevated candidal carriage, making individuals susceptible to oral candidiasis.<\/jats:p>","DOI":"10.34172\/joddd.2020.041","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T17:06:17Z","timestamp":1612890377000},"page":"206-213","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Estimation and correlation of serum and salivary glucose and immunoglobulin A levels and salivary candidal carriage in diabetic and non-diabetic patients"],"prefix":"10.34172","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7459-5172","authenticated-orcid":true,"given":"Shruthi S","family":"Hegde","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Srinivas Institute of Dental Sciences, Mukka, Surathkal, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atul P","family":"Sattur","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, SDM College of Dental Sciences and Hospital, Dharwad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil Bapu","family":"Bargale","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gayathri S","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Srinivas Institute of Dental Sciences, Mukka, Surathkal, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeeth S","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Srinivas Institute of Dental Sciences, Mukka, Surathkal, Mangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghavendra D","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Department of Microbiology, SDM College of Medical Sciences and Hospital, Dharwad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajantha G","family":"S","sequence":"additional","affiliation":[{"name":"Department of Microbiology, SDM College of Medical Sciences and Hospital, Dharwad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2004.01019.x"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Diabetes--a global threat. 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