{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:54:38Z","timestamp":1782921278231,"version":"3.54.5"},"reference-count":0,"publisher":"Maad Rayan Publishing Company","issue":"4","content-domain":{"domain":["joddd.tbzmed.ac.ir"],"crossmark-restriction":false},"short-container-title":["J Dent Res Dent Clin Dent Prospects"],"published-print":{"date-parts":[[2024,12,14]]},"abstract":"<jats:p>Background. Candida albicans in the oral cavity causes denture-induced stomatitis, but current treatments have side effects and contribute to drug resistance. Selenium nanoparticles (SeNPs) show promise as an antimicrobial agent, but their effectiveness against C. albicans is unknown and warrants further research. Methods. Acrylic resins containing different concentrations of SeNPs (0.2, 2, and 10 g\/mL) were formulated and evaluated against C. albicans isolates. The minimum inhibitory concentration (MIC) of SeNPs was determined, and a fungal biofilm was developed on acrylic samples. The quantity of biofilm was assessed using scanning electron microscopy (SEM) and optical density (OD) at 570 nm after staining with crystal violet. Statistical analysis was performed using STATA software, with Kruskal-Wallis and Mann-Whitney tests to establish significance (P&lt;0.05). Results. The MIC of SeNPs was 25%. The OD in the group with 10% SeNPs was 0.477 and 0.547 in the group with 0.2%. Kruskal-Wallis test results showed that at least two groups among those studied had significant differences (P=0.0273). In pairwise comparisons, the differences between all the groups were statistically significant (P=0.049). SEM analysis confirmed the destruction of C. albicans cell walls, leading to reduced colonization, with the 10% group showing the highest efficacy. Conclusion. The study demonstrated that SeNPs are effective against C. albicans colonization when combined with acrylic resin. Specifically, SeNPs exhibited enhanced antifungal properties at a concentration of 10%. These findings confirm that SeNPs are a promising alternative to traditional antifungal agents for treating oral candidiasis and denture-induced stomatitis. <\/jats:p>","DOI":"10.34172\/joddd.41113","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T10:07:15Z","timestamp":1734430035000},"page":"258-263","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Evaluating the anti-<i>Candida<\/i> effects of selenium nanoparticles impregnated in acrylic resins: An in vitro study"],"prefix":"10.34172","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9418-401X","authenticated-orcid":true,"given":"Masomeh","family":"Rostamzadeh","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyyed Amin","family":"Sadeghi Sangdehi","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himen","family":"Salimizand","sequence":"additional","affiliation":[{"name":"Department of Vaccinology and Immunotherapeutics, School of Public Health, University of Saskatchewan, Saskatoon, SK, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1503-6532","authenticated-orcid":true,"given":"Farshad","family":"Rahimi","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijan","family":"Nouri","sequence":"additional","affiliation":[{"name":"Departement of Epidemiology & Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"20123","published-online":{"date-parts":[[2024,12,14]]},"container-title":["Journal of Dental Research, Dental Clinics, Dental Prospects"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/joddd.tbzmed.ac.ir\/PDF\/joddd-18-258.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/joddd.tbzmed.ac.ir\/PDF\/joddd-18-258.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T10:07:15Z","timestamp":1734430035000},"score":1,"resource":{"primary":{"URL":"https:\/\/joddd.tbzmed.ac.ir\/Article\/joddd-41113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,14]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,12,14]]},"published-print":{"date-parts":[[2024,12,14]]}},"URL":"https:\/\/doi.org\/10.34172\/joddd.41113","relation":{},"ISSN":["2008-210X","2008-2118"],"issn-type":[{"value":"2008-210X","type":"print"},{"value":"2008-2118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,14]]},"assertion":[{"value":"Tabriz University of Medical Sciences","name":"journal_owner","label":"Journal Owner"},{"value":"Tabriz University of Medical Sciences","name":"journal_publisher","label":"Journal Publisher"},{"value":"2024-03-01","order":1,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}