{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T06:14:03Z","timestamp":1744179243853},"reference-count":12,"publisher":"Maad Rayan Publishing Company","issue":"4","content-domain":{"domain":["mejdd.org"],"crossmark-restriction":false},"short-container-title":["Middle East J Dig Dis"],"published-print":{"date-parts":[[2021,6,11]]},"abstract":"<jats:p>BACKGROUND Celiac disease is a non-IgE mediated food allergy, which can cause extensive villus atrophy. Because of increased food allergen absorption, there are elevated IgA and IgG antibodies in these patients, so there is a concern about IgE antibody production against wheat and other cereals. METHODS In this study, we evaluated IgE-mediated hypersensitivity to wheat, rice, and other cereals in children with celiac disease. RESULTS 22 patients (50%) had at least one positive skin prick test to food allergens. The most frequent food allergen was peanut (31.8%), followed by wheat (18.2%), corn (9.1%), and rice (4.5%). The results revealed no significant correlation between age, sex, and the results of the skin prick test (p &gt;0.05). The correlation between diagnosis time of celiac disease and results of skin prick test was also not significant statistically (p &gt;0.05). CONCLUSION Because of the high prevalence of IgE mediated hypersensitivity to cereals and beans in children with celiac disease, a skin prick test might be considered in these patients, especially in refractory cases.<\/jats:p>","DOI":"10.34172\/mejdd.2021.244","type":"journal-article","created":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T08:22:03Z","timestamp":1643271723000},"page":"339-342","update-policy":"http:\/\/dx.doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence of IgE-Mediated Food Hypersensitivity to Cereals and Beans Based on Skin Prick Test in Children with Celiac Disease"],"prefix":"10.34172","volume":"13","author":[{"given":"Ali","family":"Jafari","sequence":"first","affiliation":[{"name":"Clinical Research Development unit of Akbar Hospital, Faculty of Medicine, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somayeh","family":"Kayvanloo","sequence":"additional","affiliation":[{"name":"Clinical Research Development unit of Akbar Hospital, Faculty of Medicine, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasrin","family":"Moazzen","sequence":"additional","affiliation":[{"name":"Clinical Research Development unit of Akbar Hospital, Faculty of Medicine, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasrinsadat","family":"Motevalli Haghi","sequence":"additional","affiliation":[{"name":"Clinical Research Development unit of Akbar Hospital, Faculty of Medicine, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilufar","family":"Sedghi","sequence":"additional","affiliation":[{"name":"Clinical Research Development unit of Akbar Hospital, Faculty of Medicine, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Khoshkhui","sequence":"additional","affiliation":[{"name":"Allergy research center, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Ahanchian","sequence":"additional","affiliation":[{"name":"Clinical Research Development unit of Akbar Hospital, Faculty of Medicine, Mashhad University of medical sciences, Mashhad, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"R1","unstructured":"TAdkinson NF, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF et al. 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