{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:30:22Z","timestamp":1740177022884,"version":"3.37.3"},"reference-count":19,"publisher":"Maad Rayan Publishing Company","issue":"3","content-domain":{"domain":["mejdd.org"],"crossmark-restriction":false},"short-container-title":["Middle East J Dig Dis"],"published-print":{"date-parts":[[2024,7,31]]},"abstract":"<jats:p>Background: Pancreatic duct (PD) dilation could be presented in both benign and malignant diseases. Endoscopic ultrasonography (EUS) is a sensitive modality that provides both structural assessment and tissue sampling. This study aims to explore the importance of PD dilation as a potential indicator related to various pancreatobiliary pathologies identified via EUS. Methods: Among 3109 subjects who underwent EUS, 599 had evidence of dilated PD and met the inclusion criteria of this retrospective study. Also, the patients underwent EUS fine needle aspiration (EUS-FNA) to evaluate the etiology when required. All data were extracted from patients\u2019 medical records to perform statistical analysis. Results: The study sample revealed 64% being male with a median age was 65-years. Pancreatic adenocarcinoma was the most common etiology diagnosed in 236 patients (39.4%), followed by sphincter of Oddi dysfunction (SOD) in 13% of subjects. Ampullary carcinoma, common bile duct stone, and cholangiocarcinoma were found at 9.5%, 8.8%, and 6.8%, respectively. Abdominal pain was the most common symptom seen in 440 (73.4%) patients. Opium consumption was reported in 170 (28.4%) subjects. Opium consumption was significantly more prevalent in patients with SOD (P&lt;0.05). Conclusion: We suggest that PD dilation could be associated with a wide range of pancreaticobiliary pathologies, especially pancreatic neoplasms. In this regard, PD dilation should be considered as a crucial indicator of pancreatic neoplasm despite it may be associated with no clear etiologies.<\/jats:p>","DOI":"10.34172\/mejdd.2024.382","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T08:33:04Z","timestamp":1728376384000},"page":"155-159","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Different Etiologies of Dilated Pancreatic Duct Based on Endoscopic Ultrasonography Findings"],"prefix":"10.34172","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2078-213X","authenticated-orcid":true,"given":"Elham","family":"Sobhrakhshankhah","sequence":"first","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, 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