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Data were collected, categorized, and analyzed statistically. Results: Three hundred ninety-eight students were selected for analysis. Most participants had no complaints of reflux (62.8%), constipation (46%), or diarrhea (64.3%), or mild symptoms of abdominal pain (64.8%) and indigestion (85.9%). A total of 96.7% had mild or no symptoms according to GSRS. Male participants had higher reflux scores, while female participants reported more abdominal pain (P&lt;0.01). No significant correlation was found between GSRS scores and lifestyle factors. Gastrointestinal symptoms were linked to reduced quality of life and mental\/physical functioning (P&lt;0.05, P&lt;0.01). A negative correlation existed between SF-36 physical activity scores and participant sex (P&lt;0.05). Conclusion: The study found a low prevalence of gastrointestinal symptoms among MUMS students. Digestive symptoms may affect quality of life physically and psychologically, but the severity of the symptoms may not be the main determinant of these effects.<\/jats:p>","DOI":"10.34172\/mejdd.3166","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T07:31:47Z","timestamp":1792049507000},"page":"48-54","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Prevalence of Gastrointestinal Disorders and Lifestyle Habits in Medical Students of Mashhad University of Medical Sciences: A Cross-Sectional Study"],"prefix":"10.34172","volume":"18","author":[{"given":"Soroush","family":"Yazdani","sequence":"first","affiliation":[{"name":"Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanieh","family":"Salmani Izadi","sequence":"additional","affiliation":[{"name":"Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Mohammad Matin","family":"Alavi Dana","sequence":"additional","affiliation":[{"name":"Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Okati","sequence":"additional","affiliation":[{"name":"Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shayan","family":"Yaghouti","sequence":"additional","affiliation":[{"name":"Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parto","family":"Pariz","sequence":"additional","affiliation":[{"name":"Applied Biomedical Research Center, Basic Sciences Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payam","family":"Sharifan","sequence":"additional","affiliation":[{"name":"International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6280-7246","authenticated-orcid":true,"given":"Zahra","family":"Gholamnezhad","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"20123","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Sperber AD, Bangdiwala SI, Drossman DA, Ghoshal UC, Simren M, Tack J, et al. 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