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\u0441\u0432\u043e\u0435\u0432\u0440\u0435-\u043c\u0435\u043d\u043d\u043e\u0433\u043e \u0438 \u0443\u0434\u0430\u0447\u043d\u043e\u0433\u043e \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u043d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u043e \u0432\u043d\u0438\u043c\u0430\u0442\u0435\u043b\u044c\u043d\u043e \u0441\u043e\u0431\u0440\u0430\u0442\u044c \u0430\u043d\u0430\u043c\u043d\u0435\u0437, \u0436\u0430\u043b\u043e\u0431\u044b \u0438 \u043f\u0440\u043e\u0432\u0435\u0441\u0442\u0438 \u0432\u0441\u0435 \u043d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u044b\u0435 \u0430\u043d\u0430\u043b\u0438\u0437\u044b \u0438 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f.<\/jats:p>\n                                                                                            <jats:p>Purpose. The prevalence of multiple myeloma is 2\u20134 cases for 100 000 people. The ratio of men and women is 1.6:1,the average age is 65 years. Representatives of the black race are 2 times more likely to have it than the Caucasian people. The etiology of the disease is unknown, but the role ofchromosomal and genetic factors, radiation and chemicals is considered. It should be noted that the presence of anemia may be an advantage or the only reason for a diagnostic search.Materials and methods. Diagnosis of multiple myeloma is difficult. Therefore, it is necessary to take into account all typical symptoms of this disease: bone pain (at night or during rest), renal failure, hypercalcemia, anemia, infections that often recur. Before making this diagnosis, it is necessary to reveal: M-protein and lytic bone damage, proteinuria of the light chains, or an excess of plasma cells in the bone marrow.Results. Patient K. (born 1957) arrived in Communal Company \"Dniprovskyi regional clinical oncology dispensary of the Dnipropetrovsk regional council\" for the study of the chest, abdomen, and pelvic CT. The data of the anamnesis were the following: over the past 20 years, there have been no injuries and accidents; she has been sick since December 2019, with complaints of pain in the pelvic bones, which was especially aggravated at night or at rest; the pain became stronger over time. In December 2019, the CT scan of the skeleton was carried out. The conclusion was the following: osteochondrosis of the spine and chronic pelvic fractures \u2013 the disk was not provided. The study in April 2020 revealed the following: symmetrical pathological fractures of the pelvic bones with soft tissue swelling, a fracture in the 11th rib on the left, and a metastasis node in the liver. Conclusion. Multiple myeloma is a rare malignant disease. It usually takes a long time from the appearance of complaints to the diagnosis, because multiple myeloma develops very slowly. Therefore, in order to make a diagnosis, the anamnesis and complaints should be carefully collected, all necessary analyses and studies should be conducted for timely and successful treatment.<\/jats:p>","DOI":"10.34883\/pi.2020.8.3.016","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T07:53:48Z","timestamp":1646898828000},"page":"271-275","source":"Crossref","is-referenced-by-count":0,"title":["Multiple Myeloma, a Clinical Case"],"prefix":"10.34883","author":[{"given":"\u041c.\u041e.","family":"\u0421\u0430\u043b\u043e","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u041e.\u041c.","family":"\u041f\u0435\u0442\u0440\u0438\u0447\u0435\u043d\u043a\u043e","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u041e.\u0418.","family":"\u0411\u0430\u043b\u0430\u0448\u043e\u0432\u0430","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0410.\u041e.","family":"\u0414\u043e\u0432\u0431\u043d\u044f","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"34055","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"Rajkumar S.V., Kumar S. (2016) Multiple myeloma: Diagnosis and treatment. Mayo Clinic Proc., vol. 91(1), pp. 101\u2013119. doi: 10.1016\/j. mayocp.2015.11.007.","DOI":"10.1016\/j.mayocp.2015.11.007"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Rajkumar V. (2016) Myeloma today: Disease definitions and treatment advances. Am J. Hematol., vol. 91(1), pp. 90\u2013100. doi: 10.1002\/ajh.24392.","DOI":"10.1002\/ajh.24236"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Attal M., Harousseau J.L., Facon T. InterGroupe Francophone du Myelome (2003) Single versus double autologous stem-cell transplantation for multiple myeloma. N. Engl. J. Med., vol. 349(26), pp. 2495\u20132502.","DOI":"10.1056\/NEJMoa032290"},{"key":"4","doi-asserted-by":"crossref","unstructured":"Badros A., Barlogie B., Morris C. (2001) High response rate in refractory and poor-risk multiple myeloma after allotransplantation using a nonmyeloablative conditioning regimen and donor lymphocyte infusions. 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