{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T07:11:02Z","timestamp":1671088262152},"reference-count":0,"publisher":"Professionals Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,14]]},"abstract":"<jats:p>\u0412\u0432\u0435\u0434\u0435\u043d\u0438\u0435. \u0412 \u043e\u0441\u043d\u043e\u0432\u0435 \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u0430\u043b\u043b\u0435\u0440\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0440\u0438\u043d\u0438\u0442\u0430 (\u0410\u0420) \u043b\u0435\u0436\u0438\u0442 \u044d\u043b\u0438\u043c\u0438\u043d\u0430\u0446\u0438\u044f \u0430\u043b\u043b\u0435\u0440\u0433\u0435\u043d\u043e\u0432, \u043c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u043e\u0437\u043d\u0430\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u044f \u0438 \u0430\u043b\u043b\u0435\u0440\u0433\u0435\u043d-\u0441\u043f\u0435\u0446\u0438\u0444\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0438\u043c\u043c\u0443\u043d\u043e\u0442\u0435\u0440\u0430\u043f\u0438\u044f (\u0410\u0421\u0418\u0422). \u0414\u043b\u044f \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u044f \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u0439 \u0410\u0420 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0438 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u044f \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0430 \u0436\u0438\u0437\u043d\u0438 \u043d\u0430\u043c\u0438 \u043f\u0440\u0435\u0434\u043b\u043e\u0436\u0435\u043d\u043e \u0434\u043e\u043f\u043e\u043b\u043d\u0438\u0442\u044c \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u0442\u0435\u0440\u0430\u043f\u0438\u044e \u0438 \u043f\u0440\u0435\u0434\u0441\u0435\u0437\u043e\u043d\u043d\u0443\u044e \u0410\u0421\u0418\u0422 \u043f\u044b\u043b\u044c\u0446\u0435\u0432\u044b\u043c\u0438 \u0430\u043b\u043b\u0435\u0440\u0433\u0435\u043d\u0430\u043c\u0438 \u043a\u0443\u0440\u0441\u043e\u043c \u043f\u043e\u0434\u0437\u0435\u043c\u043d\u043e\u0439 \u0441\u043f\u0435\u043b\u0435\u043e\u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u0432 \u0441\u0435\u0437\u043e\u043d \u043f\u0430\u043b\u0438\u043d\u0430\u0446\u0438\u0438 \u0432 \u0443\u0441\u043b\u043e\u0432\u0438\u044f\u0445 \u0413\u0423 \u00ab\u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0430\u043d\u0441\u043a\u0430\u044f \u0431\u043e\u043b\u044c\u043d\u0438\u0446\u0430 \u0441\u043f\u0435\u043b\u0435\u043e\u043b\u0435\u0447\u0435\u043d\u0438\u044f\u00bb (\u0413\u0423 \u00ab\u0420\u0411\u0421\u00bb).  \u0426\u0435\u043b\u044c. \u0421\u0440\u0430\u0432\u043d\u0438\u0442\u044c \u043a\u043b\u0438\u043d\u0438\u043a\u043e-\u0438\u043c\u043c\u0443\u043d\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0438 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0410\u0420 \u0434\u043e \u0438 \u043f\u043e\u0441\u043b\u0435 \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u0438\u044f \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u043e\u0433\u043e \u043b\u0435\u0447\u0435\u043d\u0438\u044f: \u043f\u0440\u0435\u0434\u0441\u0435\u0437\u043e\u043d\u043d\u043e\u0433\u043e \u043a\u0443\u0440\u0441\u0430 \u043f\u043e\u0434\u043a\u043e\u0436\u043d\u043e\u0439 \u0410\u0421\u0418\u0422 \u043f\u0440\u0438\u0447\u0438\u043d\u043d\u043e-\u0437\u043d\u0430\u0447\u0438\u043c\u044b\u043c \u043f\u044b\u043b\u044c\u0446\u0435\u0432\u044b\u043c \u0430\u043b\u043b\u0435\u0440\u0433\u0435\u043d\u043e\u043c \u0438 \u043a\u0443\u0440\u0441\u0430 \u043f\u043e\u0434\u0437\u0435\u043c\u043d\u043e\u0439 \u0441\u043f\u0435\u043b\u0435\u043e\u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u0432 \u0413\u0423 \u00ab\u0420\u0411\u0421\u00bb \u0432 \u0441\u0435\u0437\u043e\u043d \u043f\u0430\u043b\u0438\u043d\u0430\u0446\u0438\u0438.  \u041c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u044b \u0438 \u043c\u0435\u0442\u043e\u0434\u044b. \u0421\u043b\u0443\u0447\u0430\u0439\u043d\u044b\u043c \u043e\u0431\u0440\u0430\u0437\u043e\u043c \u0431\u044b\u043b\u043e \u043e\u0442\u043e\u0431\u0440\u0430\u043d\u043e 15 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432, \u043a\u043e\u0442\u043e\u0440\u044b\u0435 \u043f\u043e\u0441\u043b\u0435 \u0410\u0421\u0418\u0422 \u043f\u043e\u043b\u0443\u0447\u0438\u043b\u0438 \u043a\u0443\u0440\u0441 \u043f\u043e\u0434\u0437\u0435\u043c\u043d\u043e\u0439 \u0441\u043f\u0435\u043b\u0435\u043e\u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u0432 \u0413\u0423 \u00ab\u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0430\u043d\u0441\u043a\u0430\u044f \u0431\u043e\u043b\u044c\u043d\u0438\u0446\u0430 \u0441\u043f\u0435\u043b\u0435\u043e\u043b\u0435\u0447\u0435\u043d\u0438\u044f\u00bb. \u0423 \u0432\u0441\u0435\u0445 15 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u0430 \u0441\u0435\u043d\u0441\u0438\u0431\u0438\u043b\u0438\u0437\u0430\u0446\u0438\u044f \u043a \u043f\u044b\u043b\u044c\u0446\u0435\u0432\u044b\u043c \u0430\u043b\u043b\u0435\u0440\u0433\u0435\u043d\u0430\u043c. \u041a\u0430\u0436\u0434\u044b\u0439 \u0438\u0437 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u043e\u0446\u0435\u043d\u0438\u043b \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u0439 \u0410\u0420 (\u0432\u044b\u0434\u0435\u043b\u0435\u043d\u0438\u0439 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\u0441\u0435\u043d\u0441\u0438\u0431\u0438\u043b\u0438\u0437\u0430\u0446\u0438\u0438. \u0420\u0438\u043d\u043e\u0440\u0435\u044f \u0443 \u0438\u0441\u0441\u043b\u0435\u0434\u0443\u0435\u043c\u043e\u0439 \u0433\u0440\u0443\u043f\u043f\u044b \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0443\u043c\u0435\u043d\u044c\u0448\u0438\u043b\u0430\u0441\u044c \u043f\u043e\u0447\u0442\u0438 \u043d\u0430 70%. \u0417\u0430\u043b\u043e\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u043d\u043e\u0441\u0430 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0443\u043c\u0435\u043d\u044c\u0448\u0438\u043b\u0430\u0441\u044c \u043d\u0430 60%, \u043d\u0430 85% \u0443\u043c\u0435\u043d\u044c\u0448\u0438\u043b\u0441\u044f \u0437\u0443\u0434 \u043d\u043e\u0441\u0430, \u043f\u043e\u0447\u0442\u0438 \u043d\u0430 60% \u0443\u043c\u0435\u043d\u044c\u0448\u0438\u043b\u043e\u0441\u044c \u0447\u0438\u0445\u0430\u043d\u0438\u0435.  \u0412\u044b\u0432\u043e\u0434\u044b. 1. \u041a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u043e\u0435 \u043b\u0435\u0447\u0435\u043d\u0438\u0435, \u0441\u043e\u0441\u0442\u043e\u044f\u0449\u0435\u0435 \u0438\u0437 \u043a\u0443\u0440\u0441\u0430 \u0410\u0421\u0418\u0422 \u043f\u044b\u043b\u044c\u0446\u0435\u0432\u044b\u043c\u0438 \u0430\u043b\u043b\u0435\u0440\u0433\u0435\u043d\u0430\u043c\u0438 \u0438 \u043f\u043e\u0434\u0437\u0435\u043c\u043d\u043e\u0433\u043e \u0441\u043f\u0435\u043b\u0435\u043e\u043b\u0435\u0447\u0435\u043d\u0438\u044f \u0432 \u0413\u0423 \u00ab\u0420\u0411\u0421\u00bb, \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u044b\u043c \u043c\u0435\u0442\u043e\u0434\u043e\u043c \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u0410\u0420, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u043e\u0433\u043e \u043f\u044b\u043b\u044c\u0446\u043e\u0439 \u0440\u0430\u0441\u0442\u0435\u043d\u0438\u0439. 2. \u041d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u043e \u0432\u043d\u0435\u0434\u0440\u044f\u0442\u044c \u044d\u0442\u043e\u0442 \u043c\u0435\u0442\u043e\u0434 \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u0410\u0420 \u0432 \u043f\u0440\u0430\u043a\u0442\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u0440\u0430\u0431\u043e\u0442\u0443 \u0432\u0440\u0430\u0447\u0435\u0439 \u2013 \u0430\u043b\u043b\u0435\u0440\u0433\u043e\u043b\u043e\u0433\u043e\u0432-\u0438\u043c\u043c\u0443\u043d\u043e\u043b\u043e\u0433\u043e\u0432 \u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0438 \u0411\u0435\u043b\u0430\u0440\u0443\u0441\u044c.<\/jats:p>\n                                                                                            <jats:p>Introduction. The treatment of allergic rhinitis (AR) is based on allergen elimination, drug therapy and allergen-specific immunotherapy (ASIT). To reduce the clinical manifestations of AR in patients and improve the quality of life, we proposed to supplement symptomatic therapy and pre-season ASIT with pollen allergens with a course of underground speleotherapy during the palination season in the conditions of the State Institution \"Republican Speleotherapy Hospital\" (RSH).  Purpose. To compare clinical and immunological parameters in patients with AR before and after complex treatment: a pre-season course of subcutaneous ASIT with a causally significant pollen allergen and a course of underground speleotherapy at the State Institution \"RSH\" during the palination season.  Materials and methods. Randomly, 15 patients were selected who, after ASIT, received a course of underground speleotherapy at the State Institution \"Republican Hospital for Speleotherapy\". All 15 patients showed sensitization to pollen allergens. Each of the patients assessed the severity of the clinical manifestations of AR (nasal discharge, nasal congestion, sneezing and nasal itching) before and after treatment on a 4-point scale.  Results. A decrease in the size of the prick test by almost 40% indicates a decrease in the level of sensitization. Rhinorrhea in the study group of patients decreased by almost 70%. Nasal congestion of patients decreased by 60%, itching of the nose decreased by 85%, sneezing decreased by almost 60%.  Conclusions. 1. Comprehensive treatment, consisting of a course of ASIT with pollen allergens and underground speleotherapy at the State Institution \"RSH\", is an effective method of treating AR caused by plant pollen. 2. It is necessary to introduce this method of AR treatment into the practical work of allergologists and immunologists of the Republic of Belarus.<\/jats:p>","DOI":"10.34883\/pi.2022.25.6.003","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T15:08:56Z","timestamp":1671030536000},"page":"793-801","source":"Crossref","is-referenced-by-count":0,"title":["Comprehensive Treatment of Allergic Rhinitis"],"prefix":"10.34883","author":[{"given":"\u041d.\u041d.","family":"\u0421\u0430\u043d\u043d\u0438\u043a\u043e\u0432\u0430","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"34055","container-title":["\u0420\u0435\u0446\u0435\u043f\u0442"],"original-title":["\u041a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u043e\u0435 \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u0430\u043b\u043b\u0435\u0440\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0440\u0438\u043d\u0438\u0442\u0430"],"language":"ru","deposited":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T15:09:05Z","timestamp":1671030545000},"score":1,"resource":{"primary":{"URL":"https:\/\/recipe.by\/wp-content\/uploads\/2022\/12\/793-801_rec-6-2022-v25.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,14]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12,14]]}},"URL":"https:\/\/doi.org\/10.34883\/pi.2022.25.6.003","relation":{},"ISSN":["1993-4882","2414-2263"],"issn-type":[{"value":"1993-4882","type":"print"},{"value":"2414-2263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,14]]}}}