{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:01:00Z","timestamp":1784916060350,"version":"3.55.0"},"reference-count":30,"publisher":"Saint Petersburg Institute of Bioregulation and Gerontology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,29]]},"abstract":"<jats:p>\u0425\u0421\u041d \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u043d\u044b\u043c \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0435\u043c \u0432 \u0433\u0435\u0440\u0438\u0430\u0442\u0440\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043f\u0440\u0430\u043a\u0442\u0438\u043a\u0435. \u0423\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 \u0435\u0435 \u0447\u0430\u0441\u0442\u043e\u0442\u044b \u0441 \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u043e\u043c \u043e\u0431\u0443\u0441\u043b\u043e\u0432\u043b\u0435\u043d\u043e \u0441\u0442\u0440\u0435\u043c\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c \u0440\u043e\u0441\u0442\u043e\u043c \u0432 \u0441\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u043c \u043c\u0438\u0440\u0435 \u043d\u0435\u0438\u043d\u0444\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 (\u041d\u0418\u0417) \u2014 \u043e\u0436\u0438\u0440\u0435\u043d\u0438\u044f, \u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0439 \u0433\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u0438, \u0441\u0430\u0445\u0430\u0440\u043d\u043e\u0433\u043e \u0434\u0438\u0430\u0431\u0435\u0442\u0430 2-\u0433\u043e \u0442\u0438\u043f\u0430, \u0418\u0411\u0421, \u0425\u041e\u0411\u041b, \u0425\u0411\u041f. \u041e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u043d\u0435\u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u043e \u0438\u0445 \u0441\u043e\u0447\u0435\u0442\u0430\u043d\u0438\u0435. \u0426\u0435\u043b\u044c \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u2014 \u0438\u0437\u0443\u0447\u0435\u043d\u0438\u0435 \u0432\u0437\u0430\u0438\u043c\u043e\u0441\u0432\u044f\u0437\u0438 \u0431\u0438\u043e\u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432 \u0434\u0438\u0441\u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u043f\u043e\u0447\u0435\u043a \u0441 \u0444\u0430\u043a\u0442\u043e\u0440\u0430\u043c\u0438 \u0440\u0438\u0441\u043a\u0430 \u0425\u0421\u041d \u0443 \u043b\u0438\u0446 \u0441\u0440\u0435\u0434\u043d\u0435\u0433\u043e \u0438 \u043f\u043e\u0436\u0438\u043b\u043e\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \u0441 \u041d\u0418\u0417. \u0412 \u0440\u0435\u0442\u0440\u043e\u0441\u043f\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u0431\u044b\u043b\u0438 \u0432\u043a\u043b\u044e\u0447\u0435\u043d\u044b 357 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 45\u201374 \u043b\u0435\u0442, 173 \u043c\u0443\u0436\u0447\u0438\u043d\u044b \u0438 184 \u0436\u0435\u043d\u0449\u0438\u043d\u044b. \u0423 \u0432\u0441\u0435\u0445 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0430\u043d\u0430\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043b\u0438 \u0430\u043d\u0442\u0440\u043e\u043f\u043e\u043c\u0435\u0442\u0440\u0438\u0447\u0435\u0441\u043a\u0438\u0435, \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435, \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0435 \u0438 \u0438\u043d\u0441\u0442\u0440\u0443\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u044b\u0435 \u0434\u0430\u043d\u043d\u044b\u0435. \u0412\u0441\u044f \u0432\u044b\u0431\u043e\u0440\u043a\u0430 \u0431\u044b\u043b\u0430 \u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0430 \u043d\u0430 \u0434\u0432\u0435 \u0433\u0440\u0443\u043f\u043f\u044b: 1-\u044f \u2014 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441 \u041d\u0418\u0417 \u0438 \u0433\u0438\u043f\u0435\u0440\u0442\u0440\u043e\u0444\u0438\u0435\u0439 \u041b\u0416, \u0413\u041b\u0416 (n=136); 2-\u044f \u2014 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441 \u041d\u0418\u0417 \u0431\u0435\u0437 \u0413\u041b\u0416 (n=221). \u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0438, \u0447\u0442\u043e \u0432 1-\u0439 \u0433\u0440\u0443\u043f\u043f\u0435 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u041d\u0418\u0417 \u0438 \u0413\u041b\u0416 \u0432\u043e\u0437\u0440\u0430\u0441\u0442, \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0421\u0410\u0414, \u0447\u0430\u0441\u0442\u043e\u0442\u0430 \u0418\u0411\u0421, \u0446\u0435\u0440\u0435\u0431\u0440\u043e\u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439, \u0425\u0411\u041f, \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435 \u0444\u0438\u0431\u0440\u0438\u043d\u043e\u0433\u0435\u043d\u0430, \u0446\u0438\u0441\u0442\u0430\u0442\u0438\u043d\u0430 \u0421, \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0438 \u043f\u0440\u043e\u0442\u0435\u0438\u043d\u0443\u0440\u0438\u0438 \u0431\u044b\u043b\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u043e \u0432\u044b\u0448\u0435, \u0430 \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f \u0433\u0435\u043c\u043e\u0433\u043b\u043e\u0431\u0438\u043d\u0430, \u0447\u0438\u0441\u043b\u043e \u044d\u0440\u0438\u0442\u0440\u043e\u0446\u0438\u0442\u043e\u0432, \u0440\u0430\u0441\u0447\u0435\u0442\u043d\u0430\u044f \u0421\u041a\u0424 \u0438 \u0441\u043e\u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435 E\/A \u041b\u0416 \u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e \u043d\u0438\u0436\u0435, \u0447\u0435\u043c \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 2-\u0439 \u0433\u0440\u0443\u043f\u043f\u044b \u0441 \u041d\u0418\u0417 \u0431\u0435\u0437 \u0413\u041b\u0416. \u0423 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441\u0440\u0435\u0434\u043d\u0435\u0433\u043e \u0438 \u043f\u043e\u0436\u0438\u043b\u043e\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \u0441 \u041d\u0418\u0417 \u0443\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0430 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u0430\u044f \u043f\u0440\u044f\u043c\u0430\u044f \u0432\u0437\u0430\u0438\u043c\u043e\u0441\u0432\u044f\u0437\u044c \u0443\u0440\u043e\u0432\u043d\u044f \u0446\u0438\u0441\u0442\u0430\u0442\u0438\u043d\u0430 \u0421 \u0438 \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u0438 \u0442\u0440\u0438\u0433\u043b\u0438\u0446\u0435\u0440\u0438\u0434\u043e\u0432 \u043a\u0440\u043e\u0432\u0438 (r=0,163, p&lt;0,05), \u0430 \u0442\u0430\u043a\u0436\u0435 \u0443\u0440\u043e\u0432\u043d\u044f \u0446\u0438\u0441\u0442\u0430\u0442\u0438\u043d\u0430 \u0421 \u0438 \u0432\u0440\u0435\u043c\u0435\u043d\u0438 \u0437\u0430\u043c\u0435\u0434\u043b\u0435\u043d\u0438\u044f \u0434\u0438\u0430\u0441\u0442\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043d\u0430\u043f\u043e\u043b\u043d\u0435\u043d\u0438\u044f \u041b\u0416 (r=0,150, p&lt;0,05). \u041a\u0440\u043e\u043c\u0435 \u0442\u043e\u0433\u043e, \u0440\u0430\u0441\u0447\u0451\u0442\u043d\u0430\u044f \u0421\u041a\u0424 \u0437\u043d\u0430\u0447\u0438\u043c\u043e \u043a\u043e\u0440\u0440\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043b\u0430 \u0441 \u0441\u043e\u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435\u043c \u0415\/\u0410 \u041b\u0416 (r=0,181, p&lt;0,05), \u0432\u0440\u0435\u043c\u0435\u043d\u0435\u043c \u0437\u0430\u043c\u0435\u0434\u043b\u0435\u043d\u0438\u044f \u0440\u0430\u043d\u043d\u0435\u0433\u043e \u0434\u0438\u0430\u0441\u0442\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043d\u0430\u043f\u043e\u043b\u043d\u0435\u043d\u0438\u044f \u041b\u0416 (r=\u20130,211, p&lt;0,05) \u0438 \u043f\u0440\u0430\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 (r=\u20130,166, p&lt;0,05). \u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u043c\u043e\u0433\u0443\u0442 \u0441\u043b\u0443\u0436\u0438\u0442\u044c \u043a\u0430\u0440\u0434\u0438\u043e\u0440\u0435\u043d\u0430\u043b\u044c\u043d\u044b\u043c\u0438 \u043c\u0430\u0440\u043a\u0435\u0440\u0430\u043c\u0438 \u043f\u0440\u0438 \u0432\u043d\u0435\u0434\u0440\u0435\u043d\u0438\u0438 \u0433\u0435\u0440\u0438\u0430\u0442\u0440\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043f\u043e\u0434\u0445\u043e\u0434\u0430 \u0438 \u043f\u043e\u0441\u0442\u0440\u043e\u0435\u043d\u0438\u0438 \u0430\u043b\u0433\u043e\u0440\u0438\u0442\u043c\u0430 \u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f \u043c\u0435\u0436\u0434\u0438\u0441\u0446\u0438\u043f\u043b\u0438\u043d\u0430\u0440\u043d\u043e\u0439 \u043f\u043e\u043c\u043e\u0449\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430\u043c \u0441\u0440\u0435\u0434\u043d\u0435\u0433\u043e \u0438 \u043f\u043e\u0436\u0438\u043b\u043e\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \u0441 \u041d\u0418\u0417.<\/jats:p>\n                  <jats:p>Chronic heart failure (CHF) is the most common pathological condition in geriatric practice. The increasing prevalence of CHF with age is driven by the rapid global rise in non-communicable diseases (NCDs) such as obesity, arterial hypertension, type 2 diabetes mellitus, coronary artery disease (CAD), chronic obstructive pulmonary disease and chronic kidney disease (CKD); their combination is particularly unfavorable. Objective: To investigate the relationship between biomarkers of renal dysfunction and CHF risk factors in middle-aged and elderly individuals with NCDs. This retrospective study included 357 patients (173 men, 184 women) aged 45\u201374 years. Anthropometric, clinical, laboratory, and instrumental data were analyzed for all patients. The entire cohort was divided into two groups: group 1 \u2014 patients with NCDs and LVH (n=136); group 2 \u2014 patients with NCDs without LVH (n=221). Results showed that, compared to patients without LVH, those with LVH had significantly higher age, years, systolic blood pressure, prevalence of CAD, cerebrovascular disease, CKD, fibrinogen, cystatin C, creatinine, and proteinuria. Conversely, they had significantly lower hemoglobin levels, red blood cell count, estimated glomerular filtration rate (eGFR), and left ventricular (LV) E\/A ratio. In middle-aged and elderly patients with NCDs, statistically significant positive correlations were found between cystatin C levels and blood triglyceride concentration (r=0.163, p&lt;0.05), as well as between cystatin C levels and LV diastolic filling deceleration time (r=0.150, p&lt;0.05). Additionally, eGFR was correlated with LV E\/A ratio (r=0.181, p&lt;0.05), LV early diastolic filling deceleration time (r=\u22120.211, p&lt;0.05), and right ventricular deceleration time (r=\u22120.166, p&lt;0.05). The findings may serve as cardiorenal markers in implementing a geriatric approach and in developing algorithms for multidisciplinary care for middle-aged and elderly patients with NCDs.<\/jats:p>","DOI":"10.34922\/ae.2026.39.1.005","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:12:41Z","timestamp":1784913161000},"page":"55-63","source":"Crossref","is-referenced-by-count":0,"title":["\u0410\u0421\u0421\u041e\u0426\u0418\u0410\u0426\u0418\u042f \u0411\u0418\u041e\u041c\u0410\u0420\u041a\u0415\u0420\u041e\u0412 \u0414\u0418\u0421\u0424\u0423\u041d\u041a\u0426\u0418\u0418 \u041f\u041e\u0427\u0415\u041a \u0421 \u0424\u0410\u041a\u0422\u041e\u0420\u0410\u041c\u0418 \u0420\u0418\u0421\u041a\u0410 \u0420\u0410\u0417\u0412\u0418\u0422\u0418\u042f \u0425\u0420\u041e\u041d\u0418\u0427\u0415\u0421\u041a\u041e\u0419 \u0421\u0415\u0420\u0414\u0415\u0427\u041d\u041e\u0419 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\u043a\u0430\u0440\u0434\u0438\u043e\u0440\u0435\u043d\u0430\u043b\u044c\u043d\u044b\u043c \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u043e\u043c \/\/ \u041d\u0435\u0444\u0440\u043e\u043b\u043e\u0433\u0438\u044f. 2019. \u0422. 23, \u2116 S. \u0421. 26\u201327."},{"key":"5","unstructured":"\u041a\u043e\u0431\u0430\u043b\u0430\u0432\u0430 \u0416.\u0414., \u041a\u043e\u043d\u0440\u0430\u0434\u0438 \u0410.\u041e., \u041d\u0435\u0434\u043e\u0433\u043e\u0434\u0430 \u0421.\u0412. \u0438 \u0434\u0440. \u0410\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u0430\u044f \u0433\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u044f \u0443 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0445: \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 2024 \/\/ \u0420\u043e\u0441. \u043a\u0430\u0440\u0434\u0438\u043e\u043b. \u0436\u0443\u0440\u043d. 2024. \u0422. 29, \u2116 9. \u0421. 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6271."},{"key":"8","doi-asserted-by":"crossref","unstructured":"\u041c\u0438\u0448\u0430\u0433\u0438\u043d \u0412.\u0412., \u041b\u0443\u043a\u044c\u044f\u043d\u043e\u0432 \u041d.\u0413., \u041a\u043e\u0437\u043b\u043e\u0432 \u041a.\u041b. \u0425\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u043f\u043e\u0436\u0438\u043b\u043e\u0433\u043e \u0438 \u0441\u0442\u0430\u0440\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \u0441 \u043f\u043e\u0441\u0442\u0438\u043d\u0444\u0430\u0440\u043a\u0442\u043d\u043e\u0439 \u0430\u043d\u0435\u0432\u0440\u0438\u0437\u043c\u043e\u0439 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430: \u0432\u043e\u043f\u0440\u043e\u0441\u044b \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u0438, \u044d\u0442\u0438\u043e\u043b\u043e\u0433\u0438\u0438, \u0445\u0438\u0440\u0443\u0440\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043b\u0435\u0447\u0435\u043d\u0438\u044f \/\/ \u0423\u0441\u043f\u0435\u0445\u0438 \u0433\u0435\u0440\u043e\u043d\u0442\u043e\u043b. 2025. \u0422. 38, \u2116 2. \u0421.181\u2013186. https:\/\/doi.org\/10.34922\/AE.2025.38.2.002","DOI":"10.34922\/AE.2025.38.2.002"},{"key":"9","doi-asserted-by":"crossref","unstructured":"\u041c\u0443\u0440\u043a\u0430\u043c\u0438\u043b\u043e\u0432 \u0418.\u0422., \u0410\u0439\u0442\u0431\u0430\u0435\u0432 \u041a.\u0410., \u041c\u0443\u0440\u043a\u0430\u043c\u0438\u043b\u043e\u0432\u0430 \u0416.\u0410. \u0438 \u0434\u0440. \u041e\u0446\u0435\u043d\u043a\u0430 \u0444\u0430\u043a\u0442\u043e\u0440\u043e\u0432 \u0440\u0438\u0441\u043a\u0430 \u043d\u0435\u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u044b\u0445 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0438 \u043f\u043e\u0447\u0435\u0447\u043d\u044b\u0445 \u043e\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u0438\u0439 \u043f\u0440\u0438 \u0441\u0430\u0445\u0430\u0440\u043d\u043e\u043c \u0434\u0438\u0430\u0431\u0435\u0442\u0435 2-\u0433\u043e \u0442\u0438\u043f\u0430 \u0432 \u043f\u043e\u0436\u0438\u043b\u043e\u043c \u0438 \u0441\u0442\u0430\u0440\u0447\u0435\u0441\u043a\u043e\u043c \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0435 \/\/ \u041a\u043b\u0438\u043d. \u043b\u0430\u0431. \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430. 2023.\u0422. 68. \u2116 6. \u0421. 323\u2013332.","DOI":"10.51620\/0869-2084-2023-68-6-323-332"},{"key":"10","unstructured":"\u041c\u0443\u0440\u043a\u0430\u043c\u0438\u043b\u043e\u0432 \u0418.\u0422., \u0421\u0430\u0431\u0438\u0440\u043e\u0432 \u0418.\u0421., \u0410\u0439\u0442\u0431\u0430\u0435\u0432 \u041a.\u0410. \u0438 \u0434\u0440. \u041f\u043e\u0447\u0435\u0447\u043d\u0430\u044f \u0434\u0438\u0441\u0444\u0443\u043d\u043a\u0446\u0438\u044f \u0438 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0438 \u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0439 \u0436\u0435\u0441\u0442\u043a\u043e\u0441\u0442\u0438 \u0443 \u043b\u0438\u0446 \u043f\u043e\u0436\u0438\u043b\u043e\u0433\u043e \u0438 \u0441\u0442\u0430\u0440\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \/\/ \u0423\u0441\u043f\u0435\u0445\u0438 \u0433\u0435\u0440\u043e\u043d\u0442\u043e\u043b. 2018. \u0422. 31, \u2116 4. \u0421. 549\u2013555."},{"key":"11","unstructured":"\u0420\u0443\u0431\u043b\u0435\u0432 \u0412.\u042e., \u0413\u0435\u043b\u044c\u0446\u0435\u0440 \u0411.\u0418., \u0421\u0435\u0440\u0433\u0435\u0435\u0432 \u0415.\u0410. \u0438 \u0434\u0440. \u041a\u043e\u043c\u043e\u0440\u0431\u0438\u0434\u043d\u043e\u0441\u0442\u044c \u0438\u0448\u0435\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u0441\u0435\u0440\u0434\u0446\u0430 \u0438 \u0435\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u0432 \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0438 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432 \u0430\u043e\u0440\u0442\u043e\u043a\u043e\u0440\u043e\u043d\u0430\u0440\u043d\u043e\u0433\u043e \u0448\u0443\u043d\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \/\/ \u0411\u044e\u043b. \u0441\u0438\u0431\u0438\u0440\u0441\u043a\u043e\u0439 \u043c\u0435\u0434. 2022. \u0422. 21, \u2116 1. \u0421. 152\u2013161. https:\/\/doi.org\/10.20538\/1682-0363-2022-1 152-161"},{"key":"12","unstructured":"\u0420\u0443\u0434\u0435\u043d\u043a\u043e \u0422.\u0415., \u041a\u0430\u043c\u044b\u0448\u043e\u0432\u0430 \u0415.\u0421., \u0412\u0430\u0441\u0438\u043b\u044c\u0435\u0432\u0430 \u041c.\u041f. \u0438 \u0434\u0440. \u0424\u0430\u043a\u0442\u043e\u0440\u044b \u0440\u0438\u0441\u043a\u0430 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u0434\u0438\u0430\u0441\u0442\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0434\u0438\u0441\u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u043c\u0438\u043e\u043a\u0430\u0440\u0434\u0430 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0431\u043e\u043b\u0435\u0437\u043d\u044c\u044e \u043f\u043e\u0447\u0435\u043a \/\/ \u0422\u0435\u0440. \u0430\u0440\u0445. 2018. \u0422. 90, \u2116 9. \u0421. 60\u201367."},{"key":"13","unstructured":"\u0421\u043c\u0438\u043b\u044f\u043d\u0438\u043d \u0410.\u041c., \u041a\u0432\u0430\u0447\u0435\u043d\u043a\u043e \u0412.\u0418., \u041a\u043e\u0440\u043e\u043b\u044c \u0412.\u0420. \u0438 \u0434\u0440. \u0424\u0430\u043a\u0442\u043e\u0440\u044b \u0440\u0438\u0441\u043a\u0430 \u0433\u0438\u043f\u0435\u0440\u0442\u0440\u043e\u0444\u0438\u0438 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u043f\u043e\u0436\u0438\u043b\u043e\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \u0438 \u0435\u0435 \u0432\u043b\u0438\u044f\u043d\u0438\u0435 \u043d\u0430 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0435 \u0441\u043e\u0431\u044b\u0442\u0438\u044f \/\/ \u0410\u043a\u0442\u0443\u0430\u043b\u044c\u043d\u044b\u0435 \u043f\u0440\u043e\u0431\u043b. \u0442\u0435\u043e\u0440., \u044d\u043a\u0441\u043f\u0435\u0440., \u043a\u043b\u0438\u043d. \u043c\u0435\u0434. \u0438 \u0444\u0430\u0440\u043c\u0430\u0446\u0438\u0438. 2019. \u0421. 137\u2013138."},{"key":"14","unstructured":"\u0424\u043e\u043c\u0438\u043d \u0418.\u0412., \u0411\u0435\u043b\u0435\u043d\u043a\u043e\u0432 \u042e.\u041d., \u041c\u0430\u0440\u0435\u0435\u0432 \u0412.\u042e. \u0438 \u0434\u0440. \u0420\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u0425\u0421\u041d \u0432 \u0415\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u043a\u043e\u0439 \u0447\u0430\u0441\u0442\u0438 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0424\u0435\u0434\u0435\u0440\u0430\u0446\u0438\u0438 \u2014 \u0434\u0430\u043d\u043d\u044b\u0435 \u042d\u041f\u041e\u0425\u0410-\u0425\u0421\u041d \/\/ \u0421\u0435\u0440\u0434\u0435\u0447. \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c. 2006. \u0422. 7, \u2116 1. \u0421. 4\u20137."},{"key":"15","doi-asserted-by":"crossref","unstructured":"Ahmad M.I., Kazibwe R., Soliman M.Z. et al. 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