{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:00:58Z","timestamp":1784916058540,"version":"3.55.0"},"reference-count":11,"publisher":"Saint Petersburg Institute of Bioregulation and Gerontology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,29]]},"abstract":"<jats:p>\u0410\u043d\u0430\u043b\u0438\u0437 \u0434\u0435\u043c\u043e\u0433\u0440\u0430\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0442\u0440\u0435\u043d\u0434\u043e\u0432 \u043f\u043e\u0437\u0432\u043e\u043b\u044f\u0435\u0442 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0438\u0442\u044c \u0443\u0441\u0442\u043e\u0439\u0447\u0438\u0432\u0443\u044e \u0442\u0435\u043d\u0434\u0435\u043d\u0446\u0438\u044e \u0441\u0442\u0430\u0440\u0435\u043d\u0438\u044f \u043d\u0430\u0441\u0435\u043b\u0435\u043d\u0438\u044f. \u041f\u0440\u043e\u0446\u0435\u0441\u0441 \u0441\u0432\u044f\u0437\u0430\u043d \u043a\u0430\u043a \u0441\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u043c \u0440\u043e\u0436\u0434\u0430\u0435\u043c\u043e\u0441\u0442\u0438, \u0442\u0430\u043a \u0438 \u0441 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435\u043c \u043e\u0436\u0438\u0434\u0430\u0435\u043c\u043e\u0439 \u043f\u0440\u043e\u0434\u043e\u043b\u0436\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u0438 \u0436\u0438\u0437\u043d\u0438. \u041d\u0435\u0441\u043c\u043e\u0442\u0440\u044f \u043d\u0430 \u043e\u043f\u0438\u0441\u0430\u043d\u043d\u044b\u0435 \u0433\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u044b\u0435 \u0434\u0435\u043c\u043e\u0433\u0440\u0430\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0442\u0440\u0435\u043d\u0434\u044b, \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0435 \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u044f \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u043c\u0430\u043b\u043e \u0438\u0437\u0443\u0447\u0435\u043d\u043e. \u0426\u0435\u043b\u044c \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u2014 \u043e\u0446\u0435\u043d\u043a\u0430 \u043c\u0435\u0434\u0438\u043a\u043e-\u0441\u043e\u0446\u0438\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0441\u0442\u0430\u0442\u0443\u0441\u0430 \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u0427\u0435\u043b\u044f\u0431\u0438\u043d\u0441\u043a\u043e\u0439 \u043e\u0431\u043b. \u0414\u043b\u044f \u0438\u0437\u0443\u0447\u0435\u043d\u0438\u044f \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u044f \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u0431\u044b\u043b\u0430 \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u0430 \u0432\u044b\u043a\u043e\u043f\u0438\u0440\u043e\u0432\u043a\u0430 \u0434\u0430\u043d\u043d\u044b\u0445 \u043e \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430\u0445 100 \u043b\u0435\u0442 \u0438 \u0441\u0442\u0430\u0440\u0448\u0435. \u0412 \u0438\u0442\u043e\u0433\u043e\u0432\u043e\u0439 \u0431\u0430\u0437\u0435 \u0434\u0430\u043d\u043d\u044b\u0445 \u043f\u0440\u0435\u0434\u0441\u0442\u0430\u0432\u043b\u0435\u043d\u043e 72 \u0437\u0430\u043f\u0438\u0441\u0438 \u043e \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0438 \u0438 \u043f\u0430\u0440\u0430\u043c\u0435\u0442\u0440\u0430\u0445 \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u044f \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u0427\u0435\u043b\u044f\u0431\u0438\u043d\u0441\u043a\u043e\u0439 \u043e\u0431\u043b., \u0432 \u043a\u0430\u0436\u0434\u043e\u0439 \u0438\u0437 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0434\u0430\u043d\u044b \u0432\u043e\u0437\u0440\u0430\u0441\u0442, \u043f\u043e\u043b, \u0434\u0438\u0430\u0433\u043d\u043e\u0437 \u043f\u0440\u0438 \u043e\u0431\u0440\u0430\u0449\u0435\u043d\u0438\u0438, \u0430\u043d\u0442\u0440\u043e\u043f\u043e\u043c\u0435\u0442\u0440\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0438 (\u0440\u043e\u0441\u0442, \u043c\u0430\u0441\u0441\u0430 \u0442\u0435\u043b\u0430, \u0418\u041c\u0422) \u0438 \u0440\u044f\u0434 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0445 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u0439 \u043e\u0431\u0449\u0435\u0433\u043e \u0430\u043d\u0430\u043b\u0438\u0437\u0430 \u043a\u0440\u043e\u0432\u0438 \u0438 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043f\u0430\u0440\u0430\u043c\u0435\u0442\u0440\u043e\u0432. \u041d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u044b \u0432 \u043f\u043e\u043f\u0443\u043b\u044f\u0446\u0438\u0438 \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u0427\u0435\u043b\u044f\u0431\u0438\u043d\u0441\u043a\u043e\u0439 \u043e\u0431\u043b. \u0431\u044b\u043b\u0438 \u0441\u043b\u0435\u0434\u0443\u044e\u0449\u0438\u0435 \u043d\u043e\u0437\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0433\u0440\u0443\u043f\u043f\u044b: I.67 \u0414\u0440\u0443\u0433\u0438\u0435 \u0446\u0435\u0440\u0435\u0431\u0440\u043e\u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u043d\u044b\u0435 \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u2014 \u0443\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0430 \u0432 \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u0433\u043e \u0438\u043b\u0438 \u0441\u043e\u043f\u0443\u0442\u0441\u0442\u0432\u0443\u044e\u0449\u0435\u0433\u043e \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u0430 \u0443 65,27 % \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432, I.11 \u0413\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u0432\u043d\u0430\u044f \u0431\u043e\u043b\u0435\u0437\u043d\u044c \u0441\u0435\u0440\u0434\u0446\u0430 \u2014 \u0443 51,39 %, I.20 \u0421\u0442\u0435\u043d\u043e\u043a\u0430\u0440\u0434\u0438\u044f \u2014 \u0443 22,22 % \u043a\u0430\u043a \u0432 \u0433\u0440\u0443\u043f\u043f\u0435 \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u0441 \u0438\u043d\u0432\u0430\u043b\u0438\u0434\u043d\u043e\u0441\u0442\u044c\u044e, \u0442\u0430\u043a \u0438 \u0432 \u0433\u0440\u0443\u043f\u043f\u0435 \u0431\u0435\u0437 \u0434\u0430\u043d\u043d\u043e\u0433\u043e \u0441\u043e\u0446\u0438\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0441\u0442\u0430\u0442\u0443\u0441\u0430. \u0412 \u0433\u0440\u0443\u043f\u043f\u0435 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0431\u0435\u0437 \u0438\u043d\u0432\u0430\u043b\u0438\u0434\u043d\u043e\u0441\u0442\u0438 \u0434\u0438\u0430\u0433\u043d\u043e\u0437 I.11 \u0413\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u0432\u043d\u0430\u044f \u0431\u043e\u043b\u0435\u0437\u043d\u044c \u0441\u0435\u0440\u0434\u0446\u0430 \u0432 \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u0433\u043e (46,5 %) \u043f\u0440\u0438 \u043e\u0431\u0440\u0430\u0449\u0435\u043d\u0438\u0438 \u0432 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0443\u044e \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u0430\u0446\u0438\u044e \u0443\u0441\u0442\u0430\u043d\u0430\u0432\u043b\u0438\u0432\u0430\u043b\u0438 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u043e \u0447\u0430\u0449\u0435, \u0447\u0435\u043c \u0432 \u0433\u0440\u0443\u043f\u043f\u0435 \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0441 \u043e\u043f\u0438\u0441\u0430\u043d\u043d\u044b\u043c \u0441\u043e\u0446\u0438\u0430\u043b\u044c\u043d\u044b\u043c \u0441\u0442\u0430\u0442\u0443\u0441\u043e\u043c (17,24 %), p&lt;0,05. \u0421\u0443\u0449\u0435\u0441\u0442\u0432\u0443\u0435\u0442 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u043e\u0435 \u0440\u0430\u0437\u043b\u0438\u0447\u0438\u0435 \u043c\u0435\u0436\u0434\u0443 \u0447\u0438\u0441\u043b\u043e\u043c \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u043e\u0432 \u0443 \u043b\u044e\u0434\u0435\u0439 \u0441 \u0438\u043d\u0432\u0430\u043b\u0438\u0434\u043d\u043e\u0441\u0442\u044c\u044e \u2014 5 (4\u20136) \u0438 \u0431\u0435\u0437 \u0434\u0430\u043d\u043d\u043e\u0433\u043e \u0441\u0442\u0430\u0442\u0443\u0441\u0430 \u2014 3 (2\u20133,5), \u0447\u0442\u043e \u043f\u043e\u0434\u0442\u0432\u0435\u0440\u0436\u0434\u0430\u0435\u0442 \u0441\u0432\u044f\u0437\u044c \u0441\u0442\u043e\u0439\u043a\u043e\u0439 \u0443\u0442\u0440\u0430\u0442\u044b \u0442\u0440\u0443\u0434\u043e\u0441\u043f\u043e\u0441\u043e\u0431\u043d\u043e\u0441\u0442\u0438 \u0438 \u043f\u043e\u043b\u0438\u043c\u043e\u0440\u0431\u0438\u0434\u043d\u043e\u0441\u0442\u0438 (p&lt;0,001). \u0423\u0440\u043e\u0432\u0435\u043d\u044c \u0433\u043b\u044e\u043a\u043e\u0437\u044b \u0432\u0435\u043d\u043e\u0437\u043d\u043e\u0439 \u043a\u0440\u043e\u0432\u0438 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u043e \u0432\u044b\u0448\u0435 \u0432 \u0433\u0440\u0443\u043f\u043f\u0435 \u0441\u0442\u043e\u043b\u0435\u0442\u043d\u0438\u0445 \u0434\u043e\u043b\u0433\u043e\u0436\u0438\u0442\u0435\u043b\u0435\u0439 \u0431\u0435\u0437 \u0438\u043d\u0432\u0430\u043b\u0438\u0434\u043d\u043e\u0441\u0442\u0438 (p&lt;0,05).<\/jats:p>\n                  <jats:p>The analysis of demographic trends reveals a sustained pattern of population aging. This process is associated with both declining fertility rates and increasing life expectancy. Despite these well-documented global demographic shifts, the health status of centenarians remains understudied. The aim of this research is to assess the medical and social status of centenarians in the Chelyabinsk Region. To investigate the health of centenarians, data extraction was performed for patients aged 100 years and older. The final database comprises 72 records detailing the health status and parameters of hundred-year centenarians in the Chelyabinsk Region. Each entry includes age, sex, diagnosis upon presentation, anthropometric measurements (height, weight, BMI), and a range of laboratory indicators from complete blood count and biochemical panels. The most prevalent conditions among the centenarian population of the Chelyabinsk Region belong to the following nosological groups: \u00abI.67 Other cerebrovascular diseases\u00bb \u2014 recorded as either a primary or concomitant diagnosis in 65.27% of patients; \u00abI.11 Hypertensive heart disease\u00bb \u2014 51.39%; and \u00abI.20 Angina pectoris\u00bb \u2014 22.22%. These conditions were found in both the group of centenarians with disability and the group without this social status. In the group of patients without disability, the diagnosis \u00abI.11 Hypertensive heart disease\u00bb as a primary diagnosis (46.5%) upon presentation to a healthcare facility is established statistically significantly more often than in the group of centenarians with the aforementioned social status (disability) (17.24%), p&lt;0.05. A statistically significant difference exists in the number of clinical diagnoses between individuals with disability \u2014 5 (4\u20136) and those without this status \u2014 3 (2\u20133.5). This supports the assertion of a link between permanent loss of working capacity and polymorbidity (p&lt;0.001). Venous blood glucose levels are statistically significantly higher in the group of hundred-year centenarians without disability (p&lt;0.05).<\/jats:p>","DOI":"10.34922\/ae.2026.39.1.018","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:12:41Z","timestamp":1784913161000},"page":"154-159","source":"Crossref","is-referenced-by-count":0,"title":["\u041e\u0426\u0415\u041d\u041a\u0410 \u041c\u0415\u0414\u0418\u041a\u041e-\u0421\u041e\u0426\u0418\u0410\u041b\u042c\u041d\u041e\u0413\u041e \u0421\u0422\u0410\u0422\u0423\u0421\u0410 \u0421\u0422\u041e\u041b\u0415\u0422\u041d\u0418\u0425 \u0414\u041e\u041b\u0413\u041e\u0416\u0418\u0422\u0415\u041b\u0415\u0419 \u0427\u0415\u041b\u042f\u0411\u0418\u041d\u0421\u041a\u041e\u0419 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