{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:38:17Z","timestamp":1784687897497,"version":"3.55.0"},"reference-count":23,"publisher":"Central Research Institute for Epidemiology","issue":"2","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["virusjour.crie.ru"],"crossmark-restriction":false},"short-container-title":["Problems of Virology"],"abstract":"<jats:p>Introduction. The problem of vaccine-preventable infections requires assessing the state of herd immunity through serological monitoring.\r\nThe aim. To study the epidemiological features of measles, rubella and mumps and to estimate their seroprevalence in the last decade in Moscow.\r\nMaterials and methods. Forms of federal statistical observation; State reports \u00abOn the state of sanitary and epidemiological well-being of the Moscow population\u00bb; official EMISS data for 2012\u20132023 were used to conduct a retrospective analysis of incidence. Blood serum samples (n = 7458) from healthy individuals stratified by age were tested for the presence of IgG antobodies to measles, rubella and mumps using the ELISA. Statistical data processing was performed using Microsoft Excel and SPSS Statistics v.27 (IBM).\r\nResults. The analysis of epidemiological situation in Moscow in 2012\u20132023 revealed the presence of multidirectional trends: wave-like increase in the incidence of measles, stabilization of rubella cases registration and unstable incidence of mumps with an upward trend. A high prevalence of IgG antibodies to rubella virus was determined, preventing the spread of infection among the population. The formed level of herd immunity to mumps does not allow reducing the incidence to sporadic cases. The observed trend of increasing measles incidence can be explained by the accumulation of non-immune individuals among the population.\r\nConclusion. The significant proportion of seronegative individuals indicate the necessity to adjust vaccination prevention tactics and implement measures for mopping-up and catch-up immunization of the population against measles and mumps, especially in risk age groups.<\/jats:p>","DOI":"10.36233\/0507-4088-282","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T08:07:04Z","timestamp":1747728424000},"page":"133-146","update-policy":"https:\/\/doi.org\/10.36233\/0372-9311-crossmark","source":"Crossref","is-referenced-by-count":4,"title":["Characteristics of the epidemic process of measles, rubella and mumps and assessment of their seroprevalence at the present stage"],"prefix":"10.36233","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5033-6931","authenticated-orcid":false,"given":"Yana V.","family":"Simakova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9397-3762","authenticated-orcid":false,"given":"Vladimir A.","family":"Gushchin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6686-9011","authenticated-orcid":false,"given":"Tatiana A.","family":"Semenenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1152-4120","authenticated-orcid":false,"given":"Daria A.","family":"Ogarkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9422-7238","authenticated-orcid":false,"given":"Denis A.","family":"Kleymenov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8521-1741","authenticated-orcid":false,"given":"Anna V.","family":"Nozdracheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2296-6151","authenticated-orcid":false,"given":"Victor A.","family":"Manuylov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3262-4873","authenticated-orcid":false,"given":"Artem P.","family":"Tkachuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1769-5059","authenticated-orcid":false,"given":"Alexander L.","family":"Gintsburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22004","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"ref1","unstructured":"Tatochenko V.K., Ozeretskovsky N.A. Immunoprophylaxis 2020 (Reference Book). Epidemiologiya i vaktsinoprofilaktika. 2020; 19(6): 100. https:\/\/elibrary.ru\/uhbxbs (in Russian)"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Semenenko T.A., Smetanina S.V., Kolobukhina L.V., Karetkina G.N., Nozdracheva A.V., Kruzhkova I.S., et al. Measles: epidemiological features during the elimination period, modern possibilities of prevention, diagnosis and treatment. the importance of a serological study of the population immunity of the population. Methodological recommendations No. 74. Moscow; 2020. (in Russian)","DOI":"10.15690\/vramn1170"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Tsvirkun O.V., Tikhonova N.T., Turaeva N.V., Ezhlova E.B., Melnikova A.A., Gerasimova A.G., et al. Population immunity and structure of measles cases in the Russian Federation. 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Med. 2022; 11(4): 1145. https:\/\/doi.org\/10.3390\/jcm11041145","DOI":"10.3390\/jcm11041145"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Plans-Rubi\u00f3 P. Low percentages of measles vaccination coverage with two doses of vaccine and low herd immunity levels explain measles incidence and persistence of measles in the European Union in 2017\u20132018. Eur. J. Clin. Microbiol. Infect. Dis. 2019; 38(9): 1719\u201329. https:\/\/doi.org\/10.1007\/s10096-019-03604-0","DOI":"10.1007\/s10096-019-03604-0"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Semenenko T.A., Nozdracheva A.V., Asatryan M.N., Akimkin V.G., Tutelyan A.V., Shmyr I.S., et al. Multivariate analysis of the megacity population immunity to measles. Vestnik Rossiiskoi akademii meditsinskikh nauk. 2019; 74(5): 351\u201360. https:\/\/doi.org\/10.15690\/vramn1170 https:\/\/elibrary.ru\/wwtsug (in Russian)","DOI":"10.15690\/vramn1170"}],"container-title":["Problems of Virology"],"original-title":[],"link":[{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/viewFile\/16700\/967","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/viewFile\/16700\/974","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/viewFile\/16700\/974","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T08:40:01Z","timestamp":1747730401000},"score":1,"resource":{"primary":{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/view\/16700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":23,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,4,30]]}},"URL":"https:\/\/doi.org\/10.36233\/0507-4088-282","relation":{},"ISSN":["2411-2097","0507-4088"],"issn-type":[{"value":"2411-2097","type":"electronic"},{"value":"0507-4088","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,30]]}}}