{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:47:01Z","timestamp":1789480021066,"version":"build-2803163510"},"reference-count":24,"publisher":"Central Research Institute for Epidemiology","issue":"5","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["virusjour.crie.ru"],"crossmark-restriction":false},"short-container-title":["Problems of Virology"],"abstract":"<jats:p>Purpose. Mpox cases were previously common in children; recent outbreaks of clade II have mostly affected young adults. Therefore, this study examines the knowledge, attitudes, and seroprevalence of the Mpox virus among consenting participants in Ibadan.\r\nMaterials and methods. Eligible individuals were those who voluntarily participated in the study and met the inclusion criteria specified for the study. A cross-sectional survey was conducted involving 94 respondents, investigating socio-demographic factors, awareness levels, attitudes toward prevention, and infection rates. The anti-Mpox virus IgG antibody was detected quantitatively using the Enzyme-Linked Immunosorbent Assay (ELISA) technique. The data were then analyzed using the \u03c72 test, while the antibody quantification was displayed with a Box and Whisker plot; statistical significance was determined at p  0.05.\r\nResults. The majority of respondents were female (66.7%) and aged 58 years and above (20.0%). Most had tertiary (40.0%) and secondary education (34.4%). Awareness of the Mpox was moderate, with 61.1% having heard of the virus, primarily through news (20.0%) and healthcare workers (18.9%). However, knowledge gaps were evident: only 38.9% recognized symptoms, and 40.0% understood modes of transmission. Attitudes towards prevention were generally positive; 60.0% believed Mpox could be prevented, and 73.3% were willing to take a vaccine. Still, readiness to engage in screening was low; 81.1% had never been tested, and 58.9% were unaware of local test availability. Regarding seroprevalence, females showed a significantly higher infection rate (27.4%) than males (9.6%) (\u03c72 = 3.854, p = 0.050). Age-wise, the highest infection rates occurred in those  18 years (61.5%) and 53\u201357 years (66.6%) (\u03c72 = 30.817, p = 0.000), indicating significant age-related differences.\r\nConclusion. The findings highlight the need for targeted public health education, increased test access, and focused intervention strategies to improve Mpox virus prevention and control, especially among vulnerable age groups and under-informed populations.<\/jats:p>","DOI":"10.36233\/0507-4088-337","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T14:57:15Z","timestamp":1763218635000},"page":"463-470","update-policy":"https:\/\/doi.org\/10.36233\/0372-9311-crossmark","source":"Crossref","is-referenced-by-count":2,"title":["Seroprevalence of Anti-Mpox Virus IgG Antibody and Awareness of Mpox Disease in Ibadan, Southwest Nigeria"],"prefix":"10.36233","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2919-0154","authenticated-orcid":false,"given":"John Olusola","family":"Olayiwola","sequence":"additional","affiliation":[{"name":"Ajayi Crowther University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0499-6308","authenticated-orcid":false,"given":"Adesuwa Oluwatofunmi","family":"Akagbosu","sequence":"additional","affiliation":[{"name":"Ajayi Crowther University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0404-7634","authenticated-orcid":false,"given":"Oyindamola John","family":"Samson","sequence":"additional","affiliation":[{"name":"Ajayi Crowther University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4152-9803","authenticated-orcid":false,"given":"Ademola Emmanuel","family":"Alaba","sequence":"additional","affiliation":[{"name":"Ajayi Crowther University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7736-8474","authenticated-orcid":false,"given":"Babalola Sunday","family":"Aponjolosun","sequence":"additional","affiliation":[{"name":"Ajayi Crowther University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3997-1213","authenticated-orcid":false,"given":"Stephen Ademola","family":"Soyemi","sequence":"additional","affiliation":[{"name":"University College Hospital, Ibadan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22004","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Wassenaar T.M., Wanchai V., Ussery D.W. 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The changing epidemiology of human monkeypox\u2014a potential threat? A systematic review. PLoS Negl. Trop. Dis. 2022; 16(2): e0010141. https:\/\/doi.org\/10.1371\/journal.pntd.0010141","DOI":"10.1371\/journal.pntd.0010141"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Nguyen P.Y., Ajisegiri W.S., Costantino V., Chughtai A.A., MacIntyre C.R. Reemergence of human monkeypox and declining population immunity in the context of urbanization, Nigeria, 2017\u20132020. Emerg. Infect. Dis. 2021; 27(4): 1007\u201314. https:\/\/doi.org\/10.3201\/eid2704.203569","DOI":"10.3201\/203569"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Kabuga A.I., El Zowalaty M.E. A review of the monkeypox virus and a recent outbreak of skin rash disease in Nigeria. J. Med. 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WHO delivering on its commitment to protect and improve people\u2019s health: stories of healthier populations, access to services and emergency response; 2024."},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Ghazy R.M., Yazbek S., Gebreal A., Hussein M., Addai S.A., Mensah E., Sarfo M., et al. Monkeypox vaccine acceptance among Ghanaians: a call for action. Vaccines (Basel). 2023; 11(2): 240. https:\/\/doi.org\/10.3390\/vaccines11020240","DOI":"10.3390\/vaccines11020240"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Ogoina D, Mahmmod M.D., Ballah A.D., Mildred O., Nneka M.C.I., Sebastine O.O., et al. Mpox epidemiology and risk factors, Nigeria, 2022. Emerg. Infect. Dis. 2024; 30(9): 1799\u2013808. https:\/\/doi.org\/10.3201\/eid3009.240135","DOI":"10.3201\/eid3009.240135"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Mauldin M.R., McCollum A.M., Nakazawa Y.J., Mandra A., Whitehouse E.R., Davidson W., et al. Exportation of monkeypox virus from the African continent. J. Infect. 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