{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T22:26:40Z","timestamp":1778538400421,"version":"3.51.4"},"reference-count":33,"publisher":"Central Research Institute for Epidemiology","issue":"2","license":[{"start":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T00:00:00Z","timestamp":1621036800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Problems of Virology"],"abstract":"<jats:p>Introduction. Immunodeficiency underlying the development of severe forms of new coronavirus infection may be the result of mixed infection with SARS-CoV-2 and other pathogens, including Epstein\u2013Barr virus (EBV).The aim is to study the prevalence and epidemiological features of co-infection with SARS-CoV-2 and EBV. Material and methods. A cross-sectional randomized study was conducted in Moscow region from March to May 2020. Two groups were examined for EBV-markers: hospital patients (n = 95) treated for SARS-CoV-2 infection and blood donors (n = 92).Results. With equal EBV prevalence the detection of active infection markers in donors (10.9%) was noticeably lower than in SARS-CoV-2 patients (80%). Significant differences in this indicator were also found when patients from subgroups with interstitial pneumonia with the presence (96.6%) and absence (97.2%) of SARS-CoV-2 in the nasopharyngeal smear were compared with the subgroup of patients with mild COVID-19 (43.3%). The average IgG VCA and IgG EBNA positivity coefficients in donor group were higher than in patient group (p  0.05). Patients with active EBV infection markers were significantly more likely to have pneumonia, exceeding the reference values of ALT and the relative number of monocytes (odds ratio \u2013 23.6; 3.5; 9.7, respectively).Discussion. The present study examined the incidence and analyzed epidemiological features of active EBV infection in patients with COVID-19.Conclusion. A significantly higher rate of detection of active EBV infection markers in hospital patients indicates a combined participation SARS-CoV-2 and EBV in the development of interstitial pneumonia. Low levels of specific IgG EBV serve as predictors of EBV reactivation. Exceeding the reference values of ALT and the relative number of monocytes in patients should serve as a reason for examination for active EBV infection markers.<\/jats:p>","DOI":"10.36233\/0507-4088-40","type":"journal-article","created":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T18:10:13Z","timestamp":1621102213000},"page":"152-161","source":"Crossref","is-referenced-by-count":29,"title":["Reactivation of Epstein\u2013Barr virus (&lt;i&gt;Herpesviridae: Lymphocryptovirus&lt;\/i&gt;, HHV-4) infection during COVID-19: epidemiological features"],"prefix":"10.36233","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7040-7653","authenticated-orcid":false,"given":"T. V.","family":"Solomay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6686-9011","authenticated-orcid":false,"given":"T. A.","family":"Semenenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4857-9624","authenticated-orcid":false,"given":"N. N.","family":"Filatov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8992-9080","authenticated-orcid":false,"given":"S. L.","family":"Vedunova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7006-506X","authenticated-orcid":false,"given":"V. F.","family":"Lavrov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7325-0834","authenticated-orcid":false,"given":"D. I.","family":"Smirnova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-4482","authenticated-orcid":false,"given":"A. V.","family":"Gracheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7385-5083","authenticated-orcid":false,"given":"E. B.","family":"Faizuloev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22004","published-online":{"date-parts":[[2021,5,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Salzberger B., Buder F., Lampl B., Ehrenstein B., Hitzenbichler F., Hanses F. Epidemiology of SARS-CoV-2 infection and COVID-19. Internist (Berl). 2020; 61(8): 782\u20138. https:\/\/doi.org\/10.1007\/s00108-020-00834-9 (in German).","DOI":"10.1007\/s00108-020-00834-9"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"\u0410\u043a\u0438\u043c\u043a\u0438\u043d \u0412.\u0413., \u041a\u0443\u0437\u0438\u043d \u0421.\u041d., \u0421\u0435\u043c\u0435\u043d\u0435\u043d\u043a\u043e \u0422.\u0410., \u041f\u043b\u043e\u0441\u043a\u0438\u0440\u0435\u0432\u0430 \u0410.\u0410., \u0414\u0443\u0431\u043e\u0434\u0435\u043b\u043e\u0432 \u0414.\u0412., \u0422\u0438\u0432\u0430\u043d\u043e\u0432\u0430 \u0415.\u0412., \u0438 \u0434\u0440. \u0413\u0435\u043d\u0434\u0435\u0440\u043d\u043e-\u0432\u043e\u0437\u0440\u0430\u0441\u0442\u043d\u0430\u044f \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043a\u0430 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 COVID-19 \u043d\u0430 \u0440\u0430\u0437\u043d\u044b\u0445 \u044d\u0442\u0430\u043f\u0430\u0445 \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u0438 \u0432 \u041c\u043e\u0441\u043a\u0432\u0435. \u041f\u0440\u043e\u0431\u043b\u0435\u043c\u044b \u043e\u0441\u043e\u0431\u043e \u043e\u043f\u0430\u0441\u043d\u044b\u0445 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0439. 2020; (3): 27\u201335. https:\/\/doi.org\/10.21055\/0370-1069-2020-3-27-35.","DOI":"10.21055\/0370-1069-2020-3-27-35"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"\u0410\u043a\u0438\u043c\u043a\u0438\u043d \u0412.\u0413., \u041a\u0443\u0437\u0438\u043d \u0421.\u041d., \u0421\u0435\u043c\u0435\u043d\u0435\u043d\u043a\u043e \u0422.\u0410., \u0428\u0438\u043f\u0443\u043b\u0438\u043d\u0430 \u041e.\u042e., \u042f\u0446\u044b\u0448\u0438\u043d\u0430 \u0421.\u0411., \u0422\u0438\u0432\u0430\u043d\u043e\u0432\u0430 \u0415.\u0412., \u0438 \u0434\u0440. \u0417\u0430\u043a\u043e\u043d\u043e\u043c\u0435\u0440\u043d\u043e\u0441\u0442\u0438 \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u0438\u044f SARS-CoV-2 \u0432 \u0443\u0441\u043b\u043e\u0432\u0438\u044f\u0445 \u043c\u0435\u0433\u0430\u043f\u043e\u043b\u0438\u0441\u0430. \u0412\u043e\u043f\u0440\u043e\u0441\u044b \u0432\u0438\u0440\u0443\u0441\u043e\u043b\u043e\u0433\u0438\u0438. 2020; 65(4): 203\u201311. https:\/\/doi.org\/10.36233\/0507-4088-2020-65-4-203-211.","DOI":"10.21055\/preprints-3111739"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Xiong Y., Sun D., Liu Y., Fan Y., Zhao L., Li X., et al. Clinical and high-resolution CT features of the COVID-19 infection: comparison of the initial and follow-up changes. Invest. Radiol. 2020; 55(6): 332\u20139. https:\/\/doi.org\/10.1097\/RLI.0000000000000674.","DOI":"10.1097\/RLI.0000000000000674"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Zhao D., Yao F., Wang L., Zheng L., Gao Y., Ye J., et al. A comparative study on the clinical features of COVID-19 pneumonia to other pneumonias. Clin. Infect. Dis. 2020; 71(15): 756\u201361. https:\/\/doi.org\/10.1093\/cid\/ciaa247.","DOI":"10.1093\/cid\/ciaa247"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"\u041a\u043e\u0433\u0430\u043d \u0415.\u0410., \u0411\u0435\u0440\u0435\u0437\u043e\u0432\u0441\u043a\u0438\u0439 \u042e.\u0421., \u041f\u0440\u043e\u0446\u0435\u043d\u043a\u043e \u0414.\u0414., \u0411\u0430\u0433\u0434\u0430\u0441\u0430\u0440\u044f\u043d \u0422.\u0420., \u0413\u0440\u0435\u0446\u043e\u0432 \u0415.\u041c., \u0414\u0435\u043c\u0443\u0440\u0430 \u0421.\u0410., \u0438 \u0434\u0440. \u041f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0430\u043d\u0430\u0442\u043e\u043c\u0438\u044f \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u043e\u0439 SARS-CoV-2. \u0421\u0443\u0434\u0435\u0431\u043d\u0430\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430. 2020; 6(2): 8\u201330. https:\/\/doi.org\/10.19048\/2411-8729-2020-6-2-8-30.","DOI":"10.19048\/2411-8729-2020-6-2-8-30"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"\u0421\u043e\u043b\u043e\u043c\u0430\u0439 \u0422.\u0412., \u0421\u0435\u043c\u0435\u043d\u0435\u043d\u043a\u043e \u0422.\u0410., \u0418\u0432\u0430\u043d\u043e\u0432\u0430 \u041c.\u042e. \u0420\u043e\u043b\u044c \u042d\u043f\u0448\u0442\u0435\u0439\u043d\u0430\u2013\u0411\u0430\u0440\u0440 \u0432\u0438\u0440\u0443\u0441\u043d\u043e\u0439 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438 \u0438 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u043e\u0432 \u0412 \u0438 \u0421 \u0432 \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438 \u043f\u0435\u0447\u0435\u043d\u0438. \u0412\u043e\u043f\u0440\u043e\u0441\u044b \u0432\u0438\u0440\u0443\u0441\u043e\u043b\u043e\u0433\u0438\u0438. 2019; 64(5): 215\u201320. https:\/\/doi.org\/10.36233\/0507-4088-2019-64-5-215-220.","DOI":"10.36233\/0507-4088-2019-64-5-215-220"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"\u0421\u043e\u043b\u043e\u043c\u0430\u0439 \u0422.\u0412., \u0421\u0435\u043c\u0435\u043d\u0435\u043d\u043a\u043e \u0422.\u0410. \u0412\u0438\u0440\u0443\u0441\u043d\u044b\u0435 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u044b \u0412, \u0421 \u0438 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u044b\u0439 \u043c\u043e\u043d\u043e\u043d\u0443\u043a\u043b\u0435\u043e\u0437: \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0441\u0445\u043e\u0434\u0441\u0442\u0432\u043e \u0438 \u0440\u0430\u0437\u043b\u0438\u0447\u0438\u044f. \u0412\u043e\u043f\u0440\u043e\u0441\u044b \u0432\u0438\u0440\u0443\u0441\u043e\u043b\u043e\u0433\u0438\u0438. 2020; 65(1): 27\u201334. https:\/\/doi.org\/10.36233\/0507-4088-2020-65-1-27-34.","DOI":"10.36233\/0507-4088-2020-65-1-27-34"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Na I.K., Buckland M., Agostini C., Edgar J.D.M., Friman V., Michallet M., et al. Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies. Eur. J. Haematol. 2019; 102(6): 447\u201356. https:\/\/doi.org\/10.1111\/ejh.13223.","DOI":"10.1111\/ejh.13223"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Chinen J., Shearer W.T. Secondary immunodeficiencies, including HIV infection. J. Allergy Clin. Immunol. 2010; 125(2 Suppl. 2): 195\u2013203. https:\/\/doi.org\/10.1016\/j.jaci.2009.08.040.","DOI":"10.1016\/j.jaci.2009.08.040"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"\u0425\u0430\u0440\u0447\u0435\u043d\u043a\u043e \u0415.\u041f. \u041a\u043e\u0440\u043e\u043d\u0430\u0432\u0438\u0440\u0443\u0441 SARS-Cov-2: \u0441\u043b\u043e\u0436\u043d\u043e\u0441\u0442\u0438 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u0435\u0437\u0430, \u043f\u043e\u0438\u0441\u043a\u0438 \u0432\u0430\u043a\u0446\u0438\u043d \u0438 \u0431\u0443\u0434\u0443\u0449\u0438\u0435 \u043f\u0430\u043d\u0434\u0435\u043c\u0438\u0438. \u042d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u0412\u0430\u043a\u0446\u0438\u043d\u043e\u043f\u0440\u043e\u0444\u0438\u043b\u0430\u043a\u0442\u0438\u043a\u0430. 2020; 19(3): 4\u201320. https:\/\/doi.org\/10.31631\/2073-3046-2020-19-3-4-20.","DOI":"10.31631\/2073-3046-2020-19-3-4-20"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Vavougios G.D. Overlapping host pathways between SARS-CoV-2 and its potential copathogens: An in silico analysis. Infect. Genet. Evol. 2020; 86: 104602. https:\/\/doi.org\/10.1016\/j.meegid.2020.104602.","DOI":"10.1016\/j.meegid.2020.104602"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Nieto-Moro M., Ecclesia F.G., Tom\u00e9-Masa I., De Lama Caro-Pat\u00f3n G., Leoz-Gordillo I., Cabrero-Hern\u00e1ndez M., et al. SARS-CoV-2 and Streptococcus pneumoniae coinfection as a cause of severe pneumonia in an infant. Pediatr. Pulmonol. 2020; 55(9): 2198\u2013200. https:\/\/doi.org\/10.1002\/ppul.24916.","DOI":"10.1002\/ppul.24916"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"\u0421\u043e\u043b\u043e\u043c\u0430\u0439 \u0422.\u0412., \u0421\u0435\u043c\u0435\u043d\u0435\u043d\u043a\u043e \u0422.\u0410., \u041a\u0430\u0440\u0430\u0436\u0430\u0441 \u041d.\u0412., \u0420\u044b\u0431\u0430\u043b\u043a\u0438\u043d\u0430 \u0422.\u041d., \u041a\u043e\u0440\u043d\u0438\u0435\u043d\u043a\u043e \u041c.\u041d., \u0411\u043e\u0448\u044c\u044f\u043d \u0420.\u0415., \u0438 \u0434\u0440. \u041e\u0446\u0435\u043d\u043a\u0430 \u0440\u0438\u0441\u043a\u0430 \u0438\u043d\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u0433\u0435\u0440\u043f\u0435\u0441\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438 \u043f\u0440\u0438 \u043f\u0435\u0440\u0435\u043b\u0438\u0432\u0430\u043d\u0438\u0438 \u0434\u043e\u043d\u043e\u0440\u0441\u043a\u043e\u0439 \u043a\u0440\u043e\u0432\u0438 \u0438 \u0435\u0451 \u043a\u043e\u043c\u043f\u043e\u043d\u0435\u043d\u0442\u043e\u0432. \u0410\u043d\u0430\u043b\u0438\u0437 \u0440\u0438\u0441\u043a\u0430 \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u044e. 2020; (2): 135\u201342. https:\/\/doi.org\/10.21668\/health.risk\/2020.2.15.eng.","DOI":"10.21668\/health.risk\/2020.2.15.eng"},{"key":"ref15","unstructured":"\u0421\u043e\u043b\u043e\u043c\u0430\u0439 \u0422.\u0412. \u041c\u043d\u043e\u0433\u043e\u043b\u0435\u0442\u043d\u044f\u044f \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0430 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u0435\u043c\u043e\u0441\u0442\u0438 \u0438 \u0442\u0435\u0440\u0440\u0438\u0442\u043e\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0435 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u0438\u0435 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u043e\u0433\u043e \u043c\u043e\u043d\u043e\u043d\u0443\u043a\u043b\u0435\u043e\u0437\u0430. \u0417\u0434\u0440\u0430\u0432\u043e\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0424\u0435\u0434\u0435\u0440\u0430\u0446\u0438\u0438. 2019; 63(4): 186\u201392. https:\/\/doi.org\/10.18821\/0044-197X-2019-63-4-186-192."},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"\u0421\u043e\u043b\u043e\u043c\u0430\u0439 \u0422.\u0412., \u0424\u0438\u043b\u0430\u0442\u043e\u0432 \u041d.\u041d. \u0421\u0435\u0437\u043e\u043d\u043d\u043e\u0441\u0442\u044c \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u043e\u0439 \u0432\u0438\u0440\u0443\u0441\u043e\u043c \u042d\u043f\u0448\u0442\u0435\u0439\u043d\u0430\u2013\u0411\u0430\u0440\u0440. \u0416\u0443\u0440\u043d\u0430\u043b \u0438\u043d\u0444\u0435\u043a\u0442\u043e\u043b\u043e\u0433\u0438\u0438. 2020; 12(4): 93\u2013100. https:\/\/doi.org\/10.22625\/2072-6732-2020-12-4-93-100.","DOI":"10.22625\/2072-6732-2020-12-4-93-100"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Taylor G.S., Long H.M., Brooks J.M., Rickinson A.B., Hislop A.D. The immunology of Epstein\u2013Barr virus-induced disease. Annu. Rev. Immunol. 2015; 33: 787\u2013821. https:\/\/doi.org\/10.1146\/annurev-immunol-032414-112326.","DOI":"10.1146\/annurev-immunol-032414-112326"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Lehner G.F., Klein S.J., Zoller H., Peer A., Bellmann R., Joannidis M. Correlation of interleukin-6 with Epstein\u2013Barr virus levels in COVID-19. Crit. Care. 2020; 24(1): 657. https:\/\/doi.org\/10.1186\/s13054-020-03384-6.","DOI":"10.1186\/s13054-020-03384-6"},{"key":"ref19","unstructured":"Pasin F., Mascalchi Calveri M., Calabrese A., Pizzarelli G., Bongiovanni I., Andreoli M., et al. Oncolytic effect of SARS-CoV2 in a patient with NK lymphoma. Acta Biomed. 2020; 91(3): e2020047. https:\/\/doi.org\/10.23750\/abm.v91i3.10141."},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Liya G., Yuguang W., Jian L., Huaiping Y., Xue H., Jianwei H., et al. Studies on viral pneumonia related to novel coronavirus SARSCoV-2, SARS-CoV, and MERS-CoV: a literature review. APMIS. 2020; 128(6): 423\u201332. https:\/\/doi.org\/10.1111\/apm.13047.","DOI":"10.1111\/apm.13047"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Guenther J.F., Cameron J.E., Nguyen H.T., Wang Y., Sullivan D.E., Shan B., et al. Modulation of lung inflammation by the Epstein\u2013Barr virus protein Zta. Am. J. Physiol. Lung Cell. Mol. Physiol. 2010; 299(6): L771\u201384. https:\/\/doi.org\/10.1152\/ajplung.00408.2009.","DOI":"10.1152\/ajplung.00408.2009"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Tachikawa R., Tomii K., Seo R., Nagata K., Otsuka K., Nakagawa A., et al. Detection of herpes viruses by multiplex and real-time polymerase chain reaction in bronchoalveolar lavage fluid of patients with acute lung injury or acute respiratory distress syndrome. Respiration. 2014; 87(4): 279\u201386. https:\/\/doi.org\/10.1159\/000355200.","DOI":"10.1159\/000355200"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Aslan N., Watkin L.B., Gil A., Mishra R., Clark F.G., Welsh R.M., et al. Severity of acute infectious mononucleosis correlates with cross-reactive influenza CD8 T-cell receptor repertoires. mBio. 2017; 8(6): e01841-17. https:\/\/doi.org\/10.1128\/mBio.01841-17.","DOI":"10.1128\/mBio.01841-17"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"He C.-S., Handzlik M., Muhamad A., Gleeson M. Influence of CMV\/EBV serostatus on respiratory infection incidence during 4 months of winter training in a student cohort of endurance athletes. Eur. J. Appl. Physiol. 2013; 113(10): 2613\u20139. https:\/\/doi.org\/10.1007\/s00421-013-2704-x.","DOI":"10.1007\/s00421-013-2704-x"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Morand A., Roquelaure B., Colson P., Amrane S., Bosdure E., Raoult D., et al. Child with liver transplant recovers from COVID-19 infection. A case report. Arch. Pediatr. 2020; 27(5): 275\u20136. https:\/\/doi.org\/10.1016\/j.arcped.2020.05.004.","DOI":"10.1016\/j.arcped.2020.05.004"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Mart\u00ednez F.J., Moreno-Artero E., Jahnke S. SARS-CoV-2 and EBV coinfection. Med. Clin. (Barc.). 2020; 155(7): 319\u201320. https:\/\/doi.org\/10.1016\/j.medcle.2020.06.010.","DOI":"10.1016\/j.medcle.2020.06.010"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Wang Y., Liu S., Liu H., Li W., Lin F., Jiang L., et al. SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19. J. Hepatol. 2020; 73(4): 807\u201316. https:\/\/doi.org\/10.1016\/j.jhep.2020.05.002.","DOI":"10.1016\/j.jhep.2020.05.002"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Zou X., Fang M., Li S., Wu L., Gao B., Gao H., et al. Characteristics of liver function in patients with SARS-CoV-2 and chronic HBV coinfection. Clin. Gastroenterol. Hepatol. 2021; 19(3): 597\u2013603. https:\/\/doi.org\/10.1016\/j.cgh.2020.06.017.","DOI":"10.1016\/j.cgh.2020.06.017"},{"key":"ref29","unstructured":"Ma Y.L., Xia S.Y., Wang M., Zhang S.M., Du W.H., Chen Q. Clinical features of children with SARS-CoV-2 infection: an analysis of 115 cases. Zhongguo Dang Dai Er Ke Za Zhi [Chinese journal of contemporary pediatrics]. 2020; 22(4): 290\u20133. https:\/\/doi.org\/10.7499\/j.issn.1008-8830.2003016 (in Chinese)."},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Anastasiou O.E., Korth J., Herbstreit F., Witzke O., Lange C.M. Mild versus severe liver injury in SARS-CoV-2 infection. Dig. Dis. 2021; 39: 52\u20137. https:\/\/doi.org\/10.1159\/000510758.","DOI":"10.1159\/000510758"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Ponziani F.R., Del Zompo F., Nesci A., Santopaolo F., Ianiro G., Pompili M., et al. \u201cGemelli against COVID-19\u201d group. Liver involvement is not associated with mortality: results from a large cohort of SARS-CoV-2-positive patients. Aliment. Pharmacol. Ther. 2020; 52(6): 1060\u20138. https:\/\/doi.org\/10.1111\/apt.15996.","DOI":"10.1111\/apt.15996"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Gendrot M., Andreani J., Boxberger M., Jardot P., Fonta I., Le Bideau M., et al. Antimalarial drugs inhibit the replication of SARSCoV-2: An in vitro evaluation. Travel Med. Infect. Dis. 2020; 37: 101873. https:\/\/doi.org\/10.1016\/j.tmaid.2020.101873.","DOI":"10.1016\/j.tmaid.2020.101873"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Doyno C., Sobieraj D.M., Baker W.L. Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose. Clin. Toxicol. (Phila). 2020; 59(1): 12\u201323. https:\/\/doi.org\/10.1080\/15563650.2020.1817479.","DOI":"10.1080\/15563650.2020.1817479"}],"container-title":["Problems of Virology"],"original-title":[],"link":[{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/viewFile\/499\/315","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/viewFile\/499\/315","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T13:13:11Z","timestamp":1652793191000},"score":1,"resource":{"primary":{"URL":"https:\/\/virusjour.crie.ru\/jour\/article\/view\/499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,15]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,5,15]]}},"URL":"https:\/\/doi.org\/10.36233\/0507-4088-40","relation":{},"ISSN":["2411-2097","0507-4088"],"issn-type":[{"value":"2411-2097","type":"electronic"},{"value":"0507-4088","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5,15]]}}}