{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T07:16:44Z","timestamp":1756192604669,"version":"3.28.0"},"reference-count":22,"publisher":"Sociedade Brasileira de Pneumologia e Tisiologia","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Bras Pneumol."],"abstract":"<jats:p>Objective: To compare pre-extubation physiological characteristics and ultrasound variables between patients intubated for COVID-19 compared to a clinical population and those intubated for other reasons. Methods: This was a secondary analysis of a prospective cohort study of patients undergoing invasive mechanical ventilation (IMV) for more than 48 h. Patients were divided into two groups: those intubated for COVID-19-induced ARDS and those intubated for other clinical reasons. Ultrasound assessment of lung and diaphragm function was performed before extubation. The results were compared between the two groups of patients. Results: In comparison with the patients without COVID-19, those with the disease were younger (a median age of 58 [46-76] years vs. a median age of 75 [69-85] years; p = 0.01), had fewer comorbidities (a median Charlson Comorbidity Index of 2 [1-4] vs. a median Charlson Comorbidity Index of 5 [4-6]; p &lt; 0.01), and were less severely ill at admission (a median APACHE II score of 9 [8-14] vs. a median APACHE II score of 18 [13-22]; p &lt; 0.01). In addition, the median duration of IMV was longer in the COVID-19 patients (11 [9-23] days vs. 6 [3-8] days; p &lt; 0.01). Although extubation success rates were similar between the COVID-19 and non-COVID-19 groups (22 [71%] vs. 35 [77.8%]), median lung ultrasound score differed between the two groups (23 [18-25] vs. 15 [11-18]; p &lt; 0.01), as did median diaphragmatic excursion (2.1 [1.7-2.4] vs. 1.7 [1.2-2.0]; p &lt; 0.01). Conclusions: Although patients with COVID-19 requiring ventilatory support are younger and have fewer comorbidities than those intubated for other clinical reasons, they experience longer hospital stays. Although lung ultrasound score can differ between patients with and without COVID-19, these differences do not significantly translate into extubation success rates. Therefore, the utility of ultrasound scores in weaning COVID-19 patients from IMV needs further study.<\/jats:p>","DOI":"10.36416\/1806-3756\/e20240302","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T21:59:00Z","timestamp":1731448740000},"page":"e20240302","source":"Crossref","is-referenced-by-count":1,"title":["Lung ultrasound score and diaphragm ultrasound in weaning from mechanical ventilation: are they different in patients with and without COVID-19?"],"prefix":"10.36416","author":[{"given":"Laura","family":"Cordeiro Madeira1,2","sequence":"first","affiliation":[{"name":"1. Centro de Terapia Intensiva, Hospital Moinhos de Vento, Porto Alegre (RS) Brasil. 2. Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias Pneumol\u00f3gicas, Hospital de Cl\u00ednicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre (RS) Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"de Tarso Dalcin2,3","sequence":"additional","affiliation":[{"name":"2. Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias Pneumol\u00f3gicas, Hospital de Cl\u00ednicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre (RS) Brasil. 3. Servi\u00e7o de Pneumologia, Hospital de Cli\u00b4nicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre (RS) Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Heinen Schuster1","sequence":"additional","affiliation":[{"name":"1. Centro de Terapia Intensiva, Hospital Moinhos de Vento, Porto Alegre (RS) Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruna","family":"Conte1","sequence":"additional","affiliation":[{"name":"1. Centro de Terapia Intensiva, Hospital Moinhos de Vento, Porto Alegre (RS) Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Michel Wolf4","sequence":"additional","affiliation":[{"name":"4. Escrit\u00f3rio de Gest\u00e3o da Pr\u00e1tica Cl\u00ednica, Hospital Moinhos de Vento, Porto Alegre (RS) Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annia","family":"Schreiber5","sequence":"additional","affiliation":[{"name":"5. Unity Health Toronto, St. Michael's Hospital, Interdepartmental Division of Critical Care Medicine, Toronto (ON) Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Jacques","family":"Rouby6","sequence":"additional","affiliation":[{"name":"6. R\u00e9animation Polyvalente, D\u00e9partement d'Anesth\u00e9sie-R\u00e9animation, Universit\u00e8 Pierre et Marie Curie - UPMC - Sorbonne Universit\u00e9, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felippe","family":"Leopoldo Dexheimer-Neto1","sequence":"additional","affiliation":[{"name":"1. Centro de Terapia Intensiva, Hospital Moinhos de Vento, Porto Alegre (RS) Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22288","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.           Ferrara P, Albano L. COVID-19 and healthcare systems: What should we do next?. Public Health. 2020;185:1-2. https:\/\/doi.org\/10.1016\/j.puhe.2020.05.014","DOI":"10.1016\/j.puhe.2020.05.014"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2.           Remuzzi A, Remuzzi G. COVID-19 and Italy: what next? 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