{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:08:33Z","timestamp":1785413313403,"version":"3.56.0"},"reference-count":34,"publisher":"The Journal of Health Economics and Outcomes Research","issue":"1","license":[{"start":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T00:00:00Z","timestamp":1717459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0"}],"content-domain":{"domain":["jheor.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background<\/jats:title>\n Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients\u2019 preferences for attributes related to administration mode of corticosteroids in AARs.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A web-based survey was sent to a sample from the adult Swedish population (\u226518 years) with experience of corticosteroid treatment for AAR. We assessed the willingness to pay (WTP) for attributes related to corticosteroid treatment by applying a discrete choice experiment (DCE) approach. DCE attributes were administration mode, time to symptom relief, and price. The WTP for each attribute was derived using the attribute\u2019s coefficient in a logistic regression analysis. We specified a forced choice (FC) and an unforced choice (UC) model. In the FC model, the respondents chose between 2 hypothetical treatments and in the UC model, between any of 2 hypothetical treatments and their current treatment.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The final study population included 348 subjects, of which 80% were women. All the evaluated DCE attributes were significant predictors for the treatment choice (p<.001). In the FC model, the incremental WTP for an oral film compared with tablets was 409 Swedish kronor (SEK [\u2248\u20ac36.7]), with no other factors considered. In the UC model, the incremental WTP for the oral film compared with tablets was 574 SEK (\u2248\u20ac51.7). After considering the value of the respondents\u2019 current treatment, the WTP for the oral film decreased to 336 SEK (\u2248\u20ac30.3). The total WTP was reduced by 17 SEK (\u2248\u20ac1.5) per minute of shorter time to symptom relief. Subgroup analyses showed that people with circulatory symptoms and experience of swallowing difficulties related to allergy medication had higher WTP for the oral film than the average respondent.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The findings show a substantial economic benefit of the oral film vs tablets for patients with AARs in Sweden. This result remained also after compensation for the full value of the patients\u2019 current treatment.<\/jats:p>\n <\/jats:sec>","DOI":"10.36469\/001c.117589","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T16:18:32Z","timestamp":1717517912000},"update-policy":"https:\/\/doi.org\/10.36469\/00001","source":"Crossref","is-referenced-by-count":0,"title":["Treatment Preferences for Acute Allergic Reactions: A Discrete Choice Experiment"],"prefix":"10.36469","volume":"11","author":[{"given":"Sofia","family":"L\u00f6fvendahl","sequence":"first","affiliation":[{"name":"1The Swedish Institute for Health Economics, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emelie","family":"Andersson","sequence":"additional","affiliation":[{"name":"The Swedish Institute for Health Economics (IHE), Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Olofsson","sequence":"additional","affiliation":[{"name":"The Swedish Institute for Health Economics (IHE), Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Wahlberg","sequence":"additional","affiliation":[{"name":"The Swedish Institute for Health Economics (IHE), Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Bjermer","sequence":"additional","affiliation":[{"name":"Lund University, Lund, Sweden","department":["Department of Respiratory Medicine and Allergology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6ran","family":"Tornling","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/056d84691","id-type":"ROR","asserted-by":"publisher"}],"name":"Karolinska Institutet","department":["Respiratory Medicine Division, Department of Medicine Solna"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Hjelmgren","sequence":"additional","affiliation":[{"name":"The Swedish Institute for Health Economics (IHE), Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22273","published-online":{"date-parts":[[2024,6,4]]},"reference":[{"issue":"9","key":"ref1","doi-asserted-by":"publisher","first-page":"2781","DOI":"10.1016\/j.jaip.2023.04.046","article-title":"A discrete choice experiment to assess patient preferences for asthma rescue therapy and disease management","volume":"11","author":"E. 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