{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:55:02Z","timestamp":1781740502738,"version":"3.54.5"},"reference-count":45,"publisher":"The Journal of Health Economics and Outcomes Research","issue":"2","license":[{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["jheor.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"background\"> <jats:title>Background<\/jats:title> <jats:p>Alopecia areata (AA) is an autoimmune disease of hair loss affecting people of all ages. Alopecia totalis (AT) and universalis (AU) involve scalp and total body hair loss, respectively. AA significantly affects quality of life, but evidence on the economic burden in adolescents is limited.<\/jats:p> <\/jats:sec> <jats:sec id=\"objectives\"> <jats:title>Objectives<\/jats:title> <jats:p>To assess healthcare resource utilization (HCRU) and all-cause direct healthcare costs, including out-of-pocket (OOP) costs, of US adolescents with AA.<\/jats:p> <\/jats:sec> <jats:sec id=\"methods\"> <jats:title>Methods<\/jats:title> <jats:p>IBM MarketScan\u00ae Commercial and Medicare databases were used to identify patients aged 12-17 years with \u22652 claims with AA\/AT\/AU diagnosis (prevalent cases), from October 1, 2015, to March 31, 2018, enrolled for \u226512 months before and after the first AA diagnosis (index). Patients were matched 1:3 to non-AA controls on index year, demographics, plan type, and Charlson Comorbidity Index. Per patient per year HCRU and costs were compared post-index.<\/jats:p> <\/jats:sec> <jats:sec id=\"results\"> <jats:title>Results<\/jats:title> <jats:p>Patients comprised 130 AT\/AU adolescents and 1105 non-AT\/AU adolescents (53.8% female; mean age, 14.6 years). Post-index, AT\/AU vs controls had more outpatient (14.5 vs 7.1) and dermatologist (3.6 vs 0.3) visits, higher mean plan costs ($9397 vs $2267), including medical ($7480 vs $1780) and pharmacy ($1918 vs $487) costs, and higher OOP costs ($2081 vs $751) (all <jats:italic>P<\/jats:italic>&lt;.001). The non-AT\/AU cohort vs controls had more outpatient (11.6 vs 8.0) and dermatologist (3.4 vs 0.4) visits, higher mean plan costs ($7587 vs $4496), and higher OOP costs ($1579 vs $805) (all <jats:italic>P<\/jats:italic>&lt;.001).<\/jats:p> <\/jats:sec> <jats:sec id=\"discussion\"> <jats:title>Discussion<\/jats:title> <jats:p>This large-sample, real-world analysis found that adolescents with prevalent AA had significantly higher HCRU and all-cause costs than matched controls. The greater burden was driven by more frequent outpatient visits, and higher payer medical and pharmacy costs in comparison with controls. Oral corticosteroid use was higher among patients with AT\/AU; topical and injectable corticosteroid use was higher for non-AT\/AU. Although the data preclude the identification of AA-attributable costs, the matched-control design allows an estimation of incremental all-cause costs associated with AA.<\/jats:p> <\/jats:sec> <jats:sec id=\"conclusions\"> <jats:title>Conclusions<\/jats:title> <jats:p>Adolescents with AA incurred substantial incremental healthcare costs, with greater costs incurred among those with AT\/AU. Study findings suggest that AA incurs costs as a medical condition with a high burden on adolescent patients and health plans.<\/jats:p> <\/jats:sec>","DOI":"10.36469\/001c.36229","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T17:00:04Z","timestamp":1659114004000},"update-policy":"https:\/\/doi.org\/10.36469\/00001","source":"Crossref","is-referenced-by-count":6,"title":["Healthcare Utilization and Costs Among US Adolescents With Alopecia Areata"],"prefix":"10.36469","volume":"9","author":[{"given":"Markqayne","family":"Ray","sequence":"first","affiliation":[{"name":"Pfizer Inc, Collegeville, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyse","family":"Swallow","sequence":"additional","affiliation":[{"name":"Analysis Group, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavita","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Pfizer Inc, Collegeville, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Carley","sequence":"additional","affiliation":[{"name":"Analysis Group, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanja","family":"Sikirica","sequence":"additional","affiliation":[{"name":"Pfizer Inc, Collegeville, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis","family":"Wang","sequence":"additional","affiliation":[{"name":"Analysis Group, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolae","family":"Done","sequence":"additional","affiliation":[{"name":"Analysis Group, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Signorovitch","sequence":"additional","affiliation":[{"name":"Analysis Group, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Mostaghimi","sequence":"additional","affiliation":[{"name":"3Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22273","published-online":{"date-parts":[[2022,7,29]]},"reference":[{"issue":"7","key":"ref1","doi-asserted-by":"publisher","first-page":"628","DOI":"10.4065\/70.7.628","article-title":"Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989","volume":"70","author":"Kayvon H. Safavi","year":"1995","journal-title":"Mayo Clinic Proceedings","ISSN":"https:\/\/id.crossref.org\/issn\/0025-6196","issn-type":"print"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"259","DOI":"10.2147\/ccid.s245649","article-title":"A large cross-sectional survey study of the prevalence of alopecia areata in the United States","volume":"13","author":"Michael Benigno","year":"2020","journal-title":"Clinical, Cosmetic and Investigational Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/1178-7015","issn-type":"print"},{"key":"ref3","article-title":"What you need to know about alopecia areata","author":"National Alopecia Areata Foundation","year":"2020"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3389\/fmed.2017.00112","article-title":"A practical approach to the diagnosis and management of hair loss in children and adolescents","volume":"4","author":"Liwen Xu","year":"2017","journal-title":"Frontiers in Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/2296-858X","issn-type":"print"},{"issue":"5","key":"ref5","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1111\/j.1525-1470.1996.tb00703.x","article-title":"A clinical study of childhood alopecia areata in Chandigarh, India","volume":"13","author":"Vinod K Sharma","year":"1996","journal-title":"Pediatric Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0736-8046","issn-type":"print"},{"issue":"3","key":"ref6","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1001\/archderm.1963.01590210048007","article-title":"Alopecia areata: an evaluation of 736 patients","volume":"88","author":"SIGFRID A. Muller","year":"1963","journal-title":"Archives of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-987X","issn-type":"print"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"180","DOI":"10.2340\/0001555549180188","article-title":"Alopecia areata: a follow-up investigation of outpatient material","volume":"49","author":"L. Gip","year":"1969","journal-title":"Acta Derm Venereol"},{"issue":"6","key":"ref8","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1038\/jid.1950.52","article-title":"A statistical study and consideration of endocrine influences","volume":"14","author":"Sheldon A. Walker","year":"1950","journal-title":"Journal of Investigative Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-202X","issn-type":"print"},{"issue":"1","key":"ref9","doi-asserted-by":"publisher","first-page":"17011","DOI":"10.1038\/nrdp.2017.11","article-title":"Alopecia areata","volume":"3","author":"C. Herbert Pratt","year":"2017","journal-title":"Nature Reviews Disease Primers","ISSN":"https:\/\/id.crossref.org\/issn\/2056-676X","issn-type":"print"},{"issue":"3","key":"ref10","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.jaad.2006.05.008","article-title":"Alopecia areata: a long term follow-up study of 191 patients","volume":"55","author":"Antonella Tosti","year":"2006","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"1","key":"ref11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaad.2017.04.1141","article-title":"Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis","volume":"78","author":"Lauren C. Strazzulla","year":"2018","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"9","key":"ref12","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1111\/j.1468-3083.2006.01676.x","article-title":"Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history","volume":"20","author":"C Goh","year":"2006","journal-title":"Journal of the European Academy of Dermatology and Venereology","ISSN":"https:\/\/id.crossref.org\/issn\/0926-9959","issn-type":"print"},{"issue":"7","key":"ref13","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1001\/jamadermatol.2013.3049","article-title":"Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States","volume":"149","author":"Kathie P. Huang","year":"2013","journal-title":"JAMA Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/2168-6068","issn-type":"print"},{"issue":"5","key":"ref14","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/j.jaad.2010.08.032","article-title":"Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study","volume":"65","author":"Szu-Ying Chu","year":"2011","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"4","key":"ref15","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1111\/ced.14507","article-title":"Comorbidities of alopecia areata: a population-based cohort study","volume":"46","author":"A. Egeberg","year":"2021","journal-title":"Clinical and Experimental Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0307-6938","issn-type":"print"},{"issue":"6","key":"ref16","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1080\/14728222.2018.1481504","article-title":"Alopecia areata and the gut\u2014the link opens up for novel therapeutic interventions","volume":"22","author":"Annika Borde","year":"2018","journal-title":"Expert Opinion on Therapeutic Targets","ISSN":"https:\/\/id.crossref.org\/issn\/1472-8222","issn-type":"print"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"397","DOI":"10.2147\/ccid.s53985","article-title":"Epidemiology and burden of alopecia areata: a systematic review","volume":"8","author":"Mariya Miteva","year":"2015","journal-title":"Clinical, Cosmetic and Investigational Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/1178-7015","issn-type":"print"},{"issue":"1","key":"ref18","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1038\/jidsymp.2013.18","article-title":"Health-related quality of life (HRQoL) in alopecia areata patients\u2014a secondary analysis of the National Alopecia Areata Registry Data","volume":"16","author":"Qiuling Shi","year":"2013","journal-title":"Journal of Investigative Dermatology Symposium Proceedings","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0024","issn-type":"print"},{"issue":"3","key":"ref19","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/0010-440x(91)90045-e","article-title":"Lifetime prevalence of psychiatric disorders in patients with alopecia areata","volume":"32","author":"Eduardo A. Col\u00f3n","year":"1991","journal-title":"Comprehensive Psychiatry","ISSN":"https:\/\/id.crossref.org\/issn\/0010-440X","issn-type":"print"},{"issue":"3","key":"ref20","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1016\/j.jaad.2018.01.048","article-title":"Alopecia areata is associated with impaired health-related quality of life: a survey of affected adults and children and their families","volume":"79","author":"Lucy Y. Liu","year":"2018","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"11","key":"ref21","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1111\/j.1365-4632.2008.03743.x","article-title":"Comorbidity of psychiatric disorders in children and adolescents with alopecia areata in a child and adolescent psychiatry clinical sample","volume":"47","author":"Ahmad Ghanizadeh","year":"2008","journal-title":"Int J Dermatol","ISSN":"https:\/\/id.crossref.org\/issn\/0011-9059","issn-type":"print"},{"issue":"16","key":"ref22","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1056\/nejmra1103442","article-title":"Alopecia areata","volume":"366","author":"Amos Gilhar","year":"2012","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"6","key":"ref23","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1111\/j.1365-2230.1989.tb02604.x","article-title":"Juvenile versus maturity-onset alopecia areata\u2014a comparative retrospective clinical study","volume":"14","author":"F.B. De Waard-van der Spek","year":"1989","journal-title":"Clinical and Experimental Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0307-6938","issn-type":"print"},{"issue":"9","key":"ref24","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1001\/jamadermatol.2014.709","article-title":"Global burden of skin disease as reflected in Cochrane Database of Systematic Reviews","volume":"150","author":"Chante Karimkhani","year":"2014","journal-title":"JAMA Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/2168-6068","issn-type":"print"},{"issue":"3","key":"ref25","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.jaad.2015.04.039","article-title":"Comparing cutaneous research funded by the US National Institutes of Health (NIH) with the US skin disease burden","volume":"73","author":"Erika L. Hagstrom","year":"2015","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"1","key":"ref26","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1111\/ajd.12913","article-title":"Systemic treatments for alopecia areata: a systematic review","volume":"60","author":"Vivien Wai Yun Lai","year":"2019","journal-title":"Australasian Journal of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0004-8380","issn-type":"print"},{"issue":"3","key":"ref27","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1080\/14656566.2020.1854728","article-title":"Are drug treatment strategies really effective against alopecia areata?","volume":"22","author":"Teerapong Rattananukrom","year":"2021","journal-title":"Expert Opinion on Pharmacotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/1465-6566","issn-type":"print"},{"issue":"6","key":"ref28","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.jaad.2021.04.077","article-title":"Treatment of pediatric alopecia areata: a systematic review","volume":"86","author":"Virginia R. Barton","year":"2022","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"6","key":"ref29","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1111\/jdv.17187","article-title":"Therapeutic management in paediatric alopecia areata: a systematic review","volume":"35","author":"A. Wa\u015bkiel-Burnat","year":"2021","journal-title":"Journal of the European Academy of Dermatology and Venereology","ISSN":"https:\/\/id.crossref.org\/issn\/0926-9959","issn-type":"print"},{"issue":"1","key":"ref30","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.jaad.2020.03.004","article-title":"The Alopecia Areata Consensus of Experts (ACE) study: results of an international expert opinion on treatments for alopecia areata","volume":"83","author":"Nekma Meah","year":"2020","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"1","key":"ref31","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1007\/s12016-017-8620-9","article-title":"Alopecia areata: a comprehensive review of pathogenesis and management","volume":"54","author":"Ralph M. Tr\u00fceb","year":"2018","journal-title":"Clinical Reviews in Allergy & Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/1080-0549","issn-type":"print"},{"issue":"6","key":"ref32","doi-asserted-by":"publisher","first-page":"CD004413","DOI":"10.1002\/14651858.cd004413.pub2","article-title":"Interventions for alopecia areata","volume":"2021","author":"Finola M Delamere","year":"2008","journal-title":"Cochrane Database of Systematic Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/1465-1858","issn-type":"print"},{"issue":"3","key":"ref33","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/j.1529-8019.2011.01413.x","article-title":"Alopecia areata: clinical presentation, diagnosis, and unusual cases","volume":"24","author":"ANDREAS M. Finner","year":"2011","journal-title":"Dermatol Ther","ISSN":"https:\/\/id.crossref.org\/issn\/1396-0296","issn-type":"print"},{"issue":"1","key":"ref34","doi-asserted-by":"publisher","first-page":"S62","DOI":"10.1016\/j.jisp.2020.05.007","article-title":"Burden of illness in alopecia areata: a cross-sectional online survey study","volume":"20","author":"Natasha Mesinkovska","year":"2020","journal-title":"Journal of Investigative Dermatology Symposium Proceedings","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0024","issn-type":"print"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"S379","DOI":"10.1016\/j.jval.2019.04.1853","article-title":"PSY29 economic burden of alopecia areata in a US managed care population","volume":"22","author":"J. Xenakis","year":"2019","journal-title":"Value in Health","ISSN":"https:\/\/id.crossref.org\/issn\/1098-3015","issn-type":"print"},{"issue":"4","key":"ref36","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1001\/jamadermatol.2018.5218","article-title":"Association of out-of-pocket health care costs and financial burden for patients with alopecia areata","volume":"155","author":"Sara Jiayang Li","year":"2019","journal-title":"JAMA Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/2168-6068","issn-type":"print"},{"issue":"5","key":"ref37","doi-asserted-by":"publisher","first-page":"234","DOI":"10.4103\/ijt.ijt_67_20","article-title":"Validation of case identification for alopecia areata using International Classification of Diseases coding","volume":"12","author":"Angela M Christiano","year":"2020","journal-title":"International Journal of Trichology","ISSN":"https:\/\/id.crossref.org\/issn\/0974-7753","issn-type":"print"},{"issue":"5","key":"ref38","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s00403-020-02158-y","article-title":"Challenges of securing insurance approval for oral tofacitinib for the treatment of alopecia areata: a multi-institution retrospective review","volume":"314","author":"Sheena Desai","year":"2022","journal-title":"Archives of Dermatological Research","ISSN":"https:\/\/id.crossref.org\/issn\/1432-069X","issn-type":"print"},{"issue":"3","key":"ref39","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1111\/bjd.19598","article-title":"A qualitative exploration of the experiences of adolescents with alopecia areata and their messages for healthcare professionals","volume":"184","author":"I. de Vere Hunt","year":"2021","journal-title":"British Journal of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0007-0963","issn-type":"print"},{"issue":"4","key":"ref40","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1046\/j.1525-1470.1998.1998015326.x","article-title":"Ophiasis inversus: a rare pattern of alopecia areata","volume":"15","author":"S Muralidhar","year":"1998","journal-title":"Pediatric Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0736-8046","issn-type":"print"},{"issue":"2","key":"ref41","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.jaad.2009.10.032","article-title":"Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis","volume":"62","author":"Abdullah Alkhalifah","year":"2010","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"4","key":"ref42","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1159\/000066435","article-title":"Acute diffuse and total alopecia of the female scalp: a new subtype of diffuse alopecia areata that has a favorable prognosis","volume":"205","author":"Maki Sato-Kawamura","year":"2002","journal-title":"Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/1018-8665","issn-type":"print"},{"issue":"10","key":"ref43","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1001\/archderm.112.10.1432","article-title":"Perinevoid alopecia: an unusual variety of alopecia areata","volume":"112","author":"P. Yesudian","year":"1976","journal-title":"Arch Dermatol","ISSN":"https:\/\/id.crossref.org\/issn\/0003-987X","issn-type":"print"},{"issue":"3","key":"ref44","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1016\/j.jaad.2019.08.032","article-title":"Epidemiology of alopecia areata, ophiasis, totalis, and universalis: a systematic review and meta-analysis","volume":"82","author":"Harrison H. Lee","year":"2020","journal-title":"Journal of the American Academy of Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"issue":"4","key":"ref45","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1038\/jid.2013.464","article-title":"Lifetime incidence risk of alopecia areata estimated at 2.1% by Rochester Epidemiology Project, 1990-2009","volume":"134","author":"Sultan A. Mirzoyev","year":"2014","journal-title":"Journal of Investigative Dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-202X","issn-type":"print"}],"container-title":["Journal of Health Economics and Outcomes Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jheor.org\/article\/36229-healthcare-utilization-and-costs-among-us-adolescents-with-alopecia-areata","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T17:28:47Z","timestamp":1754328527000},"score":1,"resource":{"primary":{"URL":"https:\/\/jheor.org\/article\/36229-healthcare-utilization-and-costs-among-us-adolescents-with-alopecia-areata"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,29]]},"references-count":45,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.36469\/001c.36229","relation":{},"ISSN":["2327-2236"],"issn-type":[{"value":"2327-2236","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,29]]}}}