{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:17:35Z","timestamp":1787030255393,"version":"build-2736575974"},"reference-count":19,"publisher":"The Journal of Health Economics and Outcomes Research","issue":"2","license":[{"start":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T00:00:00Z","timestamp":1690416000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["jheor.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    The quality-adjusted life-year (QALY) is a metric widely used when assessing the cost-effectiveness of drugs and other health interventions. The assessments are used in the development of recommendations for pricing, formulary placement decisions, and health policy decisions. A new bill, H.R. 485, the Protecting Health Care for All Patients Act of 2023, was approved by the US House Energy and Commerce Health Subcommittee that will, if passed, end the practice of using QALYs in all federal programs.\n                    <jats:sup>1,2<\/jats:sup>\n                  <\/jats:p>\n                  <jats:p>\n                    Proponents of the ban say that QALYs undervalue the positive effects of therapeutics on people with disabilities.\n                    <jats:sup>3<\/jats:sup>\n                    We share their concerns. Furthermore, our review of the mathematical properties of QALYs, including an analysis of quality-of-life utility (QOL utility) data recently collected from patients with inflammatory bowel disease (IBD), has led us to conclude that QALYs are an inappropriate metric of drug and treatment cost-effectiveness for all people, both disabled and nondisabled, and should not be the basis for US healthcare policy decisions.\n                  <\/jats:p>","DOI":"10.36469\/001c.83387","type":"journal-article","created":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T09:34:45Z","timestamp":1690450485000},"update-policy":"https:\/\/doi.org\/10.36469\/00001","source":"Crossref","is-referenced-by-count":12,"title":["QALYs: The Math Doesn\u2019t Work"],"prefix":"10.36469","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3380-6102","authenticated-orcid":false,"given":"Tia G.","family":"Sawhney","sequence":"first","affiliation":[{"name":"Teus Health, LLC, Newark, New Jersey, USA"},{"name":"School of Global Public Health, New York University, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Dobes","sequence":"additional","affiliation":[{"name":"Crohn's and Colitis Foundation, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirimon","family":"O'Charoen","sequence":"additional","affiliation":[{"name":"Crohn's & Colitis Foundation, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22273","published-online":{"date-parts":[[2023,7,27]]},"reference":[{"key":"ref1","article-title":"The PROMIS-Preference Score","author":"PROPr"},{"key":"ref2","article-title":"Patient-Reported Outcomes Measurement Information System (PROMIS)","author":"National Institute on Aging"},{"key":"ref3","article-title":"Digital demo versions","author":"EQ-5D","year":"2021"},{"issue":"7","key":"ref4","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.1007\/s11136-018-1842-3","article-title":"PROMIS\u00ae-29 v2.0 profile physical and mental health summary scores","volume":"27","author":"Ron D. Hays","year":"2018","journal-title":"Quality of Life Research","ISSN":"https:\/\/id.crossref.org\/issn\/0962-9343","issn-type":"print"},{"key":"ref5","article-title":"IBD Partners","author":"Crohn\u2019s & Colitis Foundation."},{"issue":"6","key":"ref6","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1097\/mlr.0000000000000912","article-title":"Choice defines QALYs: a US valuation of the EQ-5D-5L","volume":"56","author":"Benjamin M. Craig","year":"2018","journal-title":"Medical Care","ISSN":"https:\/\/id.crossref.org\/issn\/0025-7079","issn-type":"print"},{"issue":"3","key":"ref7","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/s40273-021-01109-3","article-title":"A comparison of PROPr and EQ-5D-5L value sets","volume":"40","author":"Tianxin Pan","year":"2021","journal-title":"Pharmacoeconomics","ISSN":"https:\/\/id.crossref.org\/issn\/1170-7690","issn-type":"print"},{"key":"ref8","article-title":"21st Century Cures Act, HR 34, 114 Cong","year":"2016"},{"issue":"3","key":"ref9","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol - a new facility for the measurement of health-related quality of life","volume":"16","author":"EuroQol Group","year":"1990","journal-title":"Health Policy","ISSN":"https:\/\/id.crossref.org\/issn\/0168-8510","issn-type":"print"},{"issue":"6","key":"ref10","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1007\/s40271-022-00583-x","article-title":"Patient-centered core impact sets: what they are and why we need them","volume":"15","author":"Eleanor M. Perfetto","year":"2022","journal-title":"The Patient - Patient-Centered Outcomes Research","ISSN":"https:\/\/id.crossref.org\/issn\/1178-1653","issn-type":"print"},{"key":"ref11","article-title":"New US bill challenges use of QALY in drug value assessments","year":"2023","journal-title":"HealthEconomics"},{"key":"ref12","article-title":"Energy & Commerce Committee Reports QALY ban bill for consideration by U.S","author":"Alliance for Aging Research","year":"2023","journal-title":"House of Representatives"},{"key":"ref13","article-title":"Quality-Adjusted Life Years and the Devaluation of Life with Disability: Part of the Bioethics and Disability Series National Council on Disability","author":"N. Romano","year":"2019"},{"issue":"1","key":"ref14","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/1477-7525-1-54","article-title":"The Health Utilities Index (HUI): concepts, measurement properties and applications","volume":"1","author":"John Horsman","year":"2003","journal-title":"Health and Quality of Life Outcomes","ISSN":"https:\/\/id.crossref.org\/issn\/1477-7525","issn-type":"print"},{"key":"ref15","article-title":"Constitution of the World Health Organization","author":"World Health Organization"},{"key":"ref16","article-title":"Centers for Disease Control and Prevention. Well-being concepts","year":"2018"},{"key":"ref17","article-title":"What is inflammatory bowel disease (IBD)?","author":"Centers for Disease Control and Prevention","year":"2022"},{"key":"ref18","article-title":"Ulcerative colitis","author":"ICER","year":"2020"},{"key":"ref19","author":"EQ-5D","year":"2021","unstructured":"9. EQ-5D. Published April 1, 2021. Accessed May 31, 2023. https:\/\/euroqol.org\/"}],"container-title":["Journal of Health Economics and Outcomes Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/pmid\/37522031\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T10:41:01Z","timestamp":1748860861000},"score":1,"resource":{"primary":{"URL":"https:\/\/jheor.org\/article\/83387-qalys-the-math-doesn-t-work"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,27]]},"references-count":19,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.36469\/001c.83387","relation":{},"ISSN":["2327-2236"],"issn-type":[{"value":"2327-2236","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,27]]}}}