{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T10:25:05Z","timestamp":1793960705528,"version":"4.8.0"},"reference-count":0,"publisher":"HCA Healthcare","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HCA Healthcare Journal of Medicine"],"abstract":"<jats:p>Background \nSickle cell crisis hospitalizations are emotionally and financially burdensome to patients and healthcare systems, and processes to decrease the frequency or length of stay of these crises should be examined.\n Methods \nThis is a multicenter retrospective hospital record review of sickle cell crisis hospitalizations as defined by ICD-10 codes (D57.1-4), from January 2016 through December 2019, examining inpatient medication administration records and length of stay among admitted adults aged 18\u201365 years. Patient controlled analgesia orders using morphine, hydromorphone, fentanyl and\/or merperidine at any point of an admission (n=188) were compared to admissions without any patient-controlled analgesia orders (n=2,159). The primary end point was hospital length of stay in days. A secondary analysis examining patients with or without greater than four admissions was also conducted.\nResults \nThe 1,675 patients who met criteria comprised 2,347 sickle cell hospitalizations during the four years examined. Of those admissions, 188 had at least one patient-controlled analgesic documented in their chart and had an average length of stay of 4.54 days (SD 3.34). The 2,159 admissions without any patient-controlled analgesia had an average length of stay of 5.74 days (SD 4.64). The difference of 1.2 days between the groups was statistically significant (p\u22640.0001) using a Wilcoxon signed-rank test.\n Conclusion \nAmong patients with sickle cell crises who required inpatient hospitalizations, the use of patient-controlled analgesia demonstrated a statistically significant reduction of 1.2 days in their total length of stay. These findings support potentially changing hospital protocols to increase patient-controlled analgesia utilization.<\/jats:p>","DOI":"10.36518\/2689-0216.1275","type":"journal-article","created":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T06:42:11Z","timestamp":1630478531000},"source":"Crossref","is-referenced-by-count":4,"title":["Utilization of Patient-Controlled Analgesia Reduces Length of Stay of Sickle Cell Crisis Hospitalizations"],"prefix":"10.36518","volume":"2","author":[{"given":"Brett M","family":"Prestia","sequence":"first","affiliation":[{"name":"Memorial Health University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talha","family":"Ramzan","sequence":"additional","affiliation":[{"name":"Memorial Health University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Waldron","sequence":"additional","affiliation":[{"name":"Memorial Health University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ameer","family":"Malik","sequence":"additional","affiliation":[{"name":"Orange Park Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M","family":"Pallay","sequence":"additional","affiliation":[{"name":"Memorial Health University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace R","family":"Murbach","sequence":"additional","affiliation":[{"name":"Orange Park Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Flynn","sequence":"additional","affiliation":[{"name":"HCA Healthcare Graduate Medical Education"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"PhD","given":"Eric","family":"Shaw","sequence":"additional","affiliation":[{"name":"Mercer University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Kutlar","sequence":"additional","affiliation":[{"name":"Sickle Cell Center at the Medical College of Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Lowe","sequence":"additional","affiliation":[{"name":"HCA Healthcare Graduate Medical Education"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22435","published-online":{"date-parts":[[2021,8,31]]},"container-title":["HCA Healthcare Journal of Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T09:32:31Z","timestamp":1793957551000},"score":1,"resource":{"primary":{"URL":"https:\/\/scholarlycommons.hcahealthcare.com\/hcahealthcarejournal\/vol2\/iss4\/12"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,31]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,8,31]]}},"URL":"https:\/\/doi.org\/10.36518\/2689-0216.1275","relation":{},"ISSN":["2689-0216"],"issn-type":[{"value":"2689-0216","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,31]]}}}