{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:20:56Z","timestamp":1790036456630,"version":"4.0.1"},"reference-count":0,"publisher":"Doc Design and Informatics Co. Ltd.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect Dis Clin Microbiol"],"abstract":"<jats:p>Objective: We aimed to investigate the vaccination status and the risk factors for the intensive care unit (ICU) support need of the laboratory-confirmed breakthrough COVID-19 infection inpatients. \n\nMaterials and Methods: This multi-center point-prevalence study was conducted on inpatients, divided into two groups as \u2018fully\u2019 and \u2018partially\u2019 vaccinated according to COVID-19 vaccination status. \n\nResults: Totally 516 patients were included in the study. The median age was 65 (55-77), and 53.5% (n=276) of the patients were male. Hypertension (41.9%, n=216), diabetes mellitus (DM) (31.8%, n=164), and coronary artery disease (CAD) (16.3%, n=84) were the predominant comorbidities. Patients were divided into two groups ICU (n=196) and non-ICU (n=301). Hypertension (p=0.026), DM (p=0.048), and congestive heart failure (CHF) (p=0.005) were significantly higher in ICU patients and the median age was younger among non-ICU patients (p=0.033). Of patients, 16.9% (n=87) were fully vaccinated, and this group\u2019s need for ICU support was statistically significantly lower (p=0.021). \n\nConclusion: We conclude that older age, hypertension, DM, CHF, and being partially vaccinated were associated with the need for ICU support. Therefore, all countries should continuously monitor post-vaccination breakthrough COVID-19 infections to determine the national booster vaccine administration approach that will provide vulnerable individuals the highest protection.\n\nKeywords: COVID-19 vaccine, intensive care unit, risk factor, SARS-CoV-2 infection, vaccine breakthrough infections, variant of concerns<\/jats:p>","DOI":"10.36519\/idcm.2023.216","type":"journal-article","created":{"date-parts":[[2023,7,2]],"date-time":"2023-07-02T16:22:43Z","timestamp":1688314963000},"page":"118-126","source":"Crossref","is-referenced-by-count":4,"title":["The Impact of Vaccination Among Hospitalized Patients with the Diagnosis of 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