{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:32:17Z","timestamp":1772253137548,"version":"3.50.1"},"reference-count":31,"publisher":"Sociedade Brasileira de Cardiologia","issue":"7","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento  A regurgita\u00e7\u00e3o valvar pulmonar \u00e9 uma importante complica\u00e7\u00e3o de longo prazo em pacientes com tetralogia de Fallot (TF).  Objetivo  O presente estudo tem como objetivo investigar os efeitos do implante valvar pulmonar (IVP) na anatomia e fun\u00e7\u00e3o do ventr\u00edculo direito (VD) e na evolu\u00e7\u00e3o em longo prazo da pr\u00f3tese implantada em posi\u00e7\u00e3o pulmonar.  M\u00e9todos  Uma an\u00e1lise de coorte retrospectiva e unic\u00eantrica foi realizada em 56 pacientes consecutivos com TF submetidos a IVP. O estudo incluiu pacientes de ambos os g\u00eaneros, com idade \u2265 12 anos e compreendeu avalia\u00e7\u00e3o de dados cl\u00ednicos e cir\u00fargicos, resson\u00e2ncia magn\u00e9tica cardiovascular pr\u00e9 e p\u00f3s-operat\u00f3ria e dados ecocardiogr\u00e1ficos obtidos mais de 1 ano ap\u00f3s IVP.  Resultados  Ap\u00f3s o IVP, houve uma diminui\u00e7\u00e3o significativa do volume sist\u00f3lico final do VD indexado pela \u00e1rea de superf\u00edcie corp\u00f3rea (ASC), de 89 mL\/ASC para 69 mL\/ASC (p &lt; 0,001) e do volume diast\u00f3lico final indexado do VD, de 157 mL\/ASC para 116 mL\/ASC (p &lt; 0,001). Al\u00e9m disso, houve aumento da fra\u00e7\u00e3o de eje\u00e7\u00e3o corrigida do VD [    FEVDc =  fluxo pulmonar ajustado (fluxo pulmonar anter\u00f3grado \u2212  fluxo regurgitante)  \/  volume diast\u00f3lico final do VD ] de 23% para 35% (p &lt; 0,001) e da fra\u00e7\u00e3o de eje\u00e7\u00e3o do ventr\u00edculo esquerdo de 58% para 60% (p = 0,008). No entanto, foi observado um aumento progressivo no gradiente de pico da v\u00e1lvula pulmonar ao longo do tempo, com 25% dos pacientes apresentando um gradiente superior a 60 mmHg. Pr\u00f3teses menores (tamanhos 19 a 23) foram associadas a um risco 4,3 vezes maior de gradiente &gt; 60 mmHg em compara\u00e7\u00e3o com pr\u00f3teses maiores (tamanhos 25 a 27; p = 0,029; intervalo de confian\u00e7a: 1,18 a 17,8).  Conclus\u00e3o  Conforme esperado, o IVP demonstrou melhorias nos volumes e na fun\u00e7\u00e3o do VD. O acompanhamento e a vigil\u00e2ncia a longo prazo s\u00e3o cruciais para avaliar a durabilidade da pr\u00f3tese e detectar potenciais complica\u00e7\u00f5es. O dimensionamento adequado das pr\u00f3teses \u00e9 essencial para melhorar a longevidade da pr\u00f3tese.<\/jats:p>","DOI":"10.36660\/abc.20230585","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T10:25:26Z","timestamp":1724063126000},"source":"Crossref","is-referenced-by-count":0,"title":["Efeitos de Longo Prazo do Implante Valvar Pulmonar e Evolu\u00e7\u00e3o da Pr\u00f3tese em Pacientes com Tetralogia de Fallot Corrigida"],"prefix":"10.36660","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5545-8172","authenticated-orcid":false,"given":"Luiz Fernando","family":"Caneo","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1816-0785","authenticated-orcid":false,"given":"Aida Luiza Ribeiro","family":"Turquetto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matheus Negri","family":"Boschiero","sequence":"additional","affiliation":[{"name":"Universidade S\u00e3o Francisco,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana Patrick","family":"Amato","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5909-5126","authenticated-orcid":false,"given":"Walther Yoshiharu","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana Padilha","family":"Hodas","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa Ganeko","family":"Ligeiro","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela Regina","family":"Agostinho","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5806-6780","authenticated-orcid":false,"given":"Leonardo Augusto","family":"Miana","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Tanamati","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rilvani Cavalcante","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  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