{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:33:51Z","timestamp":1772253231626,"version":"3.50.1"},"reference-count":21,"publisher":"Sociedade Brasileira de Cardiologia","issue":"6","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento: Gama-c\u00e2maras com detectores de telureto-c\u00e1dmio-zinco (CZT) permitiram a quantifica\u00e7\u00e3o da reserva de fluxo mioc\u00e1rdico (RFM), podendo aumentar a acur\u00e1cia da cintilografia mioc\u00e1rdica de perfus\u00e3o (CMP) para detectar a causa do desconforto tor\u00e1cico.  Objetivo: Avaliar o impacto cl\u00ednico da RFM para detectar a causa do desconforto tor\u00e1cico.  M\u00e9todos: 171 pacientes com desconforto tor\u00e1cico que foram submetidos a coronariografia ou angiotomografia de coron\u00e1rias tamb\u00e9m realizaram CMP e RFM num intervalo de tempo &lt;30 dias. As aquisi\u00e7\u00f5es das imagens din\u00e2micas de repouso e estresse foram iniciadas simultaneamente \u00e0 inje\u00e7\u00e3o de 99mTc sestamibi (10 e 30mCi, respectivamente), ambas com dura\u00e7\u00e3o de onze minutos, seguidas imediatamente pela aquisi\u00e7\u00e3o das imagens de perfus\u00e3o durante 5 minutos. O estresse foi realizado com dipiridamol. Uma RFM global ou por territ\u00f3rio coronariano &lt;2,0 foi classificada como anormal.  Resultados: A idade m\u00e9dia foi de 65,9\u00b110 anos (60% do sexo feminino). A avalia\u00e7\u00e3o anat\u00f4mica mostrou que 115 (67,3%) pacientes apresentavam obstru\u00e7\u00e3o coronariana significativa, sendo que, 69 apresentavam CMP anormal e 91 apresentavam RFM anormal (60,0% vs. 79,1%, p&lt;0,01). Dentre os pacientes sem obstru\u00e7\u00e3o (56 \u2013 32,7%), 7 tinham CMP anormais e 23 tinham RFM global reduzida. A realiza\u00e7\u00e3o da RFM identificou a etiologia do desconforto tor\u00e1cico em 114 pacientes enquanto a CMP identificou em 76 (66,7% vs. 44,4%, p&lt;0,001).  Conclus\u00e3o: A RFM \u00e9 uma medida fisiol\u00f3gica quantific\u00e1vel que aumenta o impacto cl\u00ednico da CMP na detec\u00e7\u00e3o da causa do desconforto tor\u00e1cico atrav\u00e9s de uma maior acur\u00e1cia para detec\u00e7\u00e3o de DAC obstrutiva e ainda possibilita identificar a presen\u00e7a de doen\u00e7a microvascular.<\/jats:p>","DOI":"10.36660\/abc.20230700","type":"journal-article","created":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T14:16:11Z","timestamp":1721916971000},"source":"Crossref","is-referenced-by-count":0,"title":["Impacto Cl\u00ednico da Avalia\u00e7\u00e3o da Reserva de Fluxo Mioc\u00e1rdico na Identifica\u00e7\u00e3o da Causa do Desconforto Tor\u00e1cico"],"prefix":"10.36660","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8071-6516","authenticated-orcid":false,"given":"Ronaldo","family":"Lima","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio de Janeiro,  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