{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:33:02Z","timestamp":1772253182151,"version":"3.50.1"},"reference-count":16,"publisher":"Sociedade Brasileira de Cardiologia","issue":"12","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento  O tratamento ideal para regurgita\u00e7\u00e3o mitral isqu\u00eamica (RMI) em pacientes com infarto do mioc\u00e1rdio sem supradesnivelamento do segmento ST (IAMSSST) \u00e9 um t\u00f3pico debatido.  Objetivo  Avaliar o resultado a longo prazo em pacientes com IAMSSST e RMI, enfatizando particularmente a compara\u00e7\u00e3o de tratamentos naqueles com RM moderada a grave.  M\u00e9todos  Inscrevemos pacientes com IAMSSST e classificamos regurgita\u00e7\u00e3o n\u00e3o\/trivial a leve como RMI insignificante e regurgita\u00e7\u00e3o moderada a grave como RMI significativa. Al\u00e9m disso, pacientes com RMI substancial foram avaliados para desfechos cl\u00ednicos de longo prazo com rela\u00e7\u00e3o a diferentes estrat\u00e9gias de tratamento. Um teste foi considerado estatisticamente significativo com base no valor de probabilidade p&lt;0,05.  Resultados  De um total de 4.189 pacientes com IAMSSST, RMI significativa foi encontrada em 7,21% dos pacientes. Um n\u00famero significativamente maior de pacientes com morte (1,21% vs. 13,24%, p&lt;0,0001), choque cardiog\u00eanico (0,46% vs. 13,24%, p&lt;0,0001) e insufici\u00eancia card\u00edaca (1,03% vs. 11,59%, p&lt;0,0001) foram encontrados durante a hospitaliza\u00e7\u00e3o em pacientes com RMI significativa. Em um acompanhamento de 2 anos, uma taxa de evento maior foi observada no grupo RMI significativa. Pacientes com RMI significativa revascularizados por interven\u00e7\u00e3o coron\u00e1ria percut\u00e2nea (ICP), cirurgia de revasculariza\u00e7\u00e3o mioc\u00e1rdica (CRM) ou cirurgia CRM+ v\u00e1lvula mitral (VM) apresentaram melhora substancial no grau de RM (32,65% vs. 6% vs. 16,98%, p&lt;0,0001) e fra\u00e7\u00e3o de eje\u00e7\u00e3o do ventr\u00edculo esquerdo (FEVE) (27,55% vs. 1% vs. 1,89%, p&lt;0,0001) em 1 ano de acompanhamento e resultados significativamente melhores foram identificados em compara\u00e7\u00e3o ao grupo de revasculariza\u00e7\u00e3o recusada e tratamento m\u00e9dico com (-5,10% vs. 15% vs. 13,21%, p=0,04) mortalidade, (-33,67% vs. 61% vs. 73,58%, p&lt;0,0001) readmiss\u00e3o e (- 15,31% vs. 27% vs. 33,96%, p=0,01) insufici\u00eancia card\u00edaca em 2 anos de acompanhamento.  Conclus\u00e3o  Maiores taxas de mortalidade e admiss\u00e3o foram observadas em pacientes com RMI significativa em compara\u00e7\u00e3o \u00e0queles com RMI insignificante. Notavelmente, pacientes com RMI significativa que passaram por ICP, CRM ou cirurgia CRM+VM apresentaram melhores resultados em compara\u00e7\u00e3o com seus equivalentes n\u00e3o revascularizados.<\/jats:p>","DOI":"10.36660\/abc.20240064","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T11:24:51Z","timestamp":1734089091000},"source":"Crossref","is-referenced-by-count":0,"title":["IAMSST e Regurgita\u00e7\u00e3o Mitral Isqu\u00eamica: Incid\u00eancia e Resultados Cl\u00ednicos de Longo Prazo com Rela\u00e7\u00e3o \u00e0 Estrat\u00e9gia de Tratamento"],"prefix":"10.36660","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3654-2373","authenticated-orcid":false,"given":"Pooja","family":"Vyas","sequence":"first","affiliation":[{"name":"U. N. 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