{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:57:26Z","timestamp":1783465046393,"version":"3.55.0"},"reference-count":21,"publisher":"Sociedade Brasileira de Cardiologia","issue":"10","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento: A rigidez arterial aumentada \u00e9 considerada atualmente um fator de risco independente para fibrila\u00e7\u00e3o atrial. No entanto, os mecanismos fisiopatol\u00f3gicos dessa arritmia ainda constituem uma lacuna no conhecimento a ser explorada.  Objetivos: Investigar a exist\u00eancia de uma associa\u00e7\u00e3o entre rigidez arterial e densidade de extrass\u00edstoles atriais em indiv\u00edduos hipertensos sem fibrila\u00e7\u00e3o atrial.  M\u00e9todos: Estudo transversal com pacientes hipertensos sem fibrila\u00e7\u00e3o atrial diagnosticada, que foram estudados com ecocardiografia speckle-tracking para avaliar o strain do \u00e1trio esquerdo e velocidade de onda de pulso car\u00f3tido-femoral (VOPcf) para avaliar a rigidez arterial. Todos os pacientes foram submetidos ao Holter de 24 horas e exames laboratoriais. O n\u00edvel de signific\u00e2ncia adotado foi de p&lt;0,05.  Resultados: Setenta pacientes de um \u00fanico centro sem doen\u00e7a cardiovascular evidente foram inclu\u00eddos. A VOPcf correlacionou-se com uma maior densidade de extrass\u00edstoles atriais no Holter de 24 horas, independentemente da massa ventricular esquerda [1,48 (1,08- 2,03), p = 0,005]. Uma VOPcf aumentada correlacionou-se com valores reduzidos de strain atrial esquerdo, com coeficientes de correla\u00e7\u00e3o de Spearman de \u22120,27 (p= 0,027) e \u22120,29 (p = 0,018) para strains bidimensionais de reservat\u00f3rio e de conduto, respectivamente.  Conclus\u00e3o: Neste estudo com pacientes hipertensos, foi poss\u00edvel demonstrar uma associa\u00e7\u00e3o entre rigidez arterial e maior densidade de arritmias atriais. Al\u00e9m disso, a rigidez arterial associou-se com valores mais baixos de strain atrial esquerdo das fun\u00e7\u00f5es de reservat\u00f3rio e de conduto.<\/jats:p>","DOI":"10.36660\/abc.20240251","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T11:19:22Z","timestamp":1730459962000},"source":"Crossref","is-referenced-by-count":2,"title":["Associa\u00e7\u00e3o entre Rigidez Arterial e Maior Densidade de Arritmia Atrial em Idosos Hipertensos sem Fibrila\u00e7\u00e3o Atrial"],"prefix":"10.36660","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0900-3681","authenticated-orcid":false,"given":"Jo\u00e3o Gabriel B.","family":"Lage","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3843-8046","authenticated-orcid":false,"given":"Alexandre L.","family":"Bortolotto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz A.","family":"Bortolotto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata G. 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