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Cardiol."],"abstract":"<jats:p>Resumo A pericardite aguda \u00e9 uma inflama\u00e7\u00e3o do peric\u00e1rdio, o revestimento que envolve o cora\u00e7\u00e3o, sendo a condi\u00e7\u00e3o inflamat\u00f3ria card\u00edaca mais comum. A doen\u00e7a afeta frequentemente adultos jovens e pode se manifestar com gravidade vari\u00e1vel. A pericardite pode ter diversas causas, incluindo infec\u00e7\u00f5es virais, doen\u00e7as autoimunes, condi\u00e7\u00f5es p\u00f3s-infarto e, recentemente, infec\u00e7\u00f5es por SARS-CoV-2 ou vacinas contra a COVID-19. Nos pa\u00edses em desenvolvimento, especialmente na \u00c1frica, a tuberculose \u00e9 a principal causa de pericardite, frequentemente associada ao HIV. O diagn\u00f3stico baseia-se em crit\u00e9rios cl\u00ednicos, como dor no peito e altera\u00e7\u00f5es no eletrocardiograma e pode ser apoiado por exames de imagem, como ecocardiograma, resson\u00e2ncia magn\u00e9tica card\u00edaca e tomografia computadorizada. A identifica\u00e7\u00e3o da etiologia \u00e9 crucial para o tratamento personalizado, embora, muitas vezes, a causa espec\u00edfica n\u00e3o seja identificada. Novas pesquisas t\u00eam destacado o papel do inflamassoma NLRP3 na fisiopatologia da pericardite, o que pode abrir caminho para novas terapias. Al\u00e9m disso, avan\u00e7os tecnol\u00f3gicos e a intelig\u00eancia artificial s\u00e3o discutidos como ferramentas promissoras para melhorar o manejo da pericardite.<\/jats:p>","DOI":"10.36660\/abc.20240572","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T14:39:17Z","timestamp":1778769557000},"source":"Crossref","is-referenced-by-count":0,"title":["Fundamentos da Pericardite Aguda: Estado da Arte"],"prefix":"10.36660","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0608-149X","authenticated-orcid":false,"given":"Gabriel de Moraes","family":"Mangas","sequence":"first","affiliation":[{"name":"Universidade Federal Fluminense,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7596-1014","authenticated-orcid":false,"given":"Jose Gregorio Valero","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense,  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