{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:33:05Z","timestamp":1772253185749,"version":"3.50.1"},"reference-count":26,"publisher":"Sociedade Brasileira de Cardiologia","issue":"11","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento  A angiotomografia computadorizada (ATC) \u00e9 amplamente utilizada como modalidade b\u00e1sica n\u00e3o invasiva para avaliar a doen\u00e7a arterial coronariana. O \u00edndice de carga inflamat\u00f3ria (IBI Inflammatory burden index) \u00e9 um indicador de inflama\u00e7\u00e3o sist\u00eamica que reflete o estado inflamat\u00f3rio. Ainda \u00e9 dif\u00edcil determinar o alto risco de infarto agudo do mioc\u00e1rdio (IAM) futuro em pacientes com placa detectada pela angiotomografia.  Objetivo  Este estudo teve como objetivo avaliar a efic\u00e1cia dos escores de C\u00e1lcio da Art\u00e9ria Coron\u00e1ria (CAC) e IBI na predi\u00e7\u00e3o do risco de IAM entre pacientes submetidos \u00e0 ATC para dor tor\u00e1cica. Buscamos avaliar o valor preditivo individual e combinado desses \u00edndices, determinar seus valores de corte ideais e comparar o risco de IAM entre grupos de pacientes com diferentes escores CAC e IBI. Tamb\u00e9m objetivamos avaliar o papel potencial desses marcadores na identifica\u00e7\u00e3o de \u201cpacientes vulner\u00e1veis\u201d com alto risco de eventos cardiovasculares futuros.  M\u00e9todos  Este estudo retrospectivo incluiu 1.235 pacientes submetidos \u00e0 ATC devido \u00e0 dor tor\u00e1cica e acompanhados por 3 anos (2,8-3,4). Os pacientes foram categorizados em tr\u00eas modelos com base em seus escores CAC e IBI. O desfecho prim\u00e1rio foi a ocorr\u00eancia de IAM durante o per\u00edodo de acompanhamento. A signific\u00e2ncia estat\u00edstica foi estabelecida em p &lt; 0,05 para todas as an\u00e1lises.  Resultados  Pacientes que apresentaram IAM apresentaram escores de IBI e CAC significativamente mais altos em compara\u00e7\u00e3o com aqueles sem ISM. A an\u00e1lise de regress\u00e3o log\u00edstica identificou o escore de CAC e o IBI como preditores independentes de ISM. A an\u00e1lise ROC determinou os valores de corte ideais para IBI (128) e CAC (102) na predi\u00e7\u00e3o de IDM. A an\u00e1lise de Kaplan-Meier revelou um gradiente significativo no risco de IAM entre os tr\u00eas modelos, com o maior risco observado em pacientes com altos escores de IBI e CAC.  Conclus\u00e3o  A combina\u00e7\u00e3o dos escores IBI e CAC proporciona melhor estratifica\u00e7\u00e3o de risco para a previs\u00e3o de IAM futuro (placa vulner\u00e1vel) em pacientes com placa detectada por angiotomografia. Essa abordagem pode facilitar estrat\u00e9gias de tratamento mais espec\u00edficas para pacientes de alto risco.<\/jats:p>","DOI":"10.36660\/abc.20250052","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T13:37:04Z","timestamp":1767965824000},"source":"Crossref","is-referenced-by-count":0,"title":["Placas Vulner\u00e1veis Detectadas por TC Card\u00edaca e Risco de Infarto Agudo do Mioc\u00e1rdio Futuro: Valor Preditivo dos Escores CAC e do \u00cdndice de Carga Inflamat\u00f3ria"],"prefix":"10.36660","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6209-1732","authenticated-orcid":false,"given":"Sefa Erdi","family":"\u00d6m\u00fcr","sequence":"first","affiliation":[{"name":"Tokat Gaziosmanpa\u015fa University,  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