{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T13:34:41Z","timestamp":1777988081573,"version":"3.51.4"},"reference-count":28,"publisher":"Sociedade Brasileira de Cardiologia","issue":"2","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento  O mixoma card\u00edaco \u00e9 o segundo tumor card\u00edaco prim\u00e1rio mais comum; no entanto, s\u00e9ries contempor\u00e2neas realizadas em centro \u00fanico que integrem estrat\u00e9gia operat\u00f3ria e desfechos cl\u00ednicos ainda s\u00e3o limitadas.  Objetivos  Descrever as abordagens operat\u00f3rias e os desfechos cl\u00ednicos de pacientes submetidos \u00e0 ressec\u00e7\u00e3o cir\u00fargica de mixomas card\u00edacos em um \u00fanico centro.  M\u00e9todos  Realizamos uma revis\u00e3o retrospectiva de 74 pacientes consecutivos submetidos \u00e0 ressec\u00e7\u00e3o cir\u00fargica de mixomas card\u00edacos com confirma\u00e7\u00e3o histol\u00f3gica entre 2014 e 2024 em um centro terci\u00e1rio de refer\u00eancia no Brasil. Foram coletados dados cl\u00ednicos, de imagem, cir\u00fargicos e de seguimento. O desfecho prim\u00e1rio foi a incid\u00eancia de eventos tromboemb\u00f3licos. Foi adotado um n\u00edvel de signific\u00e2ncia de 5% para todas as an\u00e1lises estat\u00edsticas.  Resultados  A idade mediana foi de 60 anos (intervalo 52-66), e 68,9% dos pacientes eram do sexo feminino. O seguimento mediano foi de 60 meses (intervalo interquartil 40-79). Eventos tromboemb\u00f3licos ocorreram em 14 pacientes (18,9%), incluindo acidente vascular encef\u00e1lico (13,5%), infarto do mioc\u00e1rdio emb\u00f3lico (2,7%) e embolia pulmonar (2,7%). Na an\u00e1lise multivariada de Cox, o diabetes foi independentemente associado a menor risco de eventos tromboemb\u00f3licos (HR 0,11; intervalo de confian\u00e7a de 95% [IC 95%] 0,006-0,740; p &lt; 0,05), enquanto a fibrila\u00e7\u00e3o atrial p\u00f3s-operat\u00f3ria foi associada a maior risco tromboemb\u00f3lico (HR 6,74; IC 95% 1,490-30,510; p &lt; 0,05). Recorr\u00eancia tumoral ocorreu em 2,7% dos casos. Apenas um \u00f3bito foi registrado durante o seguimento.  Conclus\u00e3o  Os mixomas card\u00edacos est\u00e3o associados a riscos tromboemb\u00f3licos e hemodin\u00e2micos significativos. A ressec\u00e7\u00e3o cir\u00fargica precoce proporciona excelentes desfechos em longo prazo e deve ser considerada mesmo em pacientes assintom\u00e1ticos. Em nossa coorte, a morfologia tumoral apresentou uma tend\u00eancia n\u00e3o significativa para maior risco de eventos tromboemb\u00f3licos.<\/jats:p>","DOI":"10.36660\/abc.20250596","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T16:28:48Z","timestamp":1775838528000},"source":"Crossref","is-referenced-by-count":0,"title":["Experi\u00eancia Operat\u00f3ria e Desfechos Cl\u00ednicos em Pacientes com Mixoma Card\u00edaco: Um Estudo Retrospectivo de Centro \u00danico"],"prefix":"10.36660","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5938-8053","authenticated-orcid":false,"given":"Heleut\u00e9rio da Concei\u00e7\u00e3o Nicolau","family":"Madogolele","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7550-8912","authenticated-orcid":false,"given":"Manuela Cristina Ribeiro 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