{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T16:09:13Z","timestamp":1784650153130,"version":"3.55.0"},"reference-count":31,"publisher":"Sociedade Brasileira de Cardiologia","issue":"4","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento: A insufici\u00eancia tric\u00faspide (IT) \u00e9 prevalente e seu manejo permanece desafiador, com alta mortalidade na cirurgia isolada, indica\u00e7\u00e3o tardia \u00e0 interven\u00e7\u00e3o e recente expans\u00e3o de terapias transcateter. No Brasil, h\u00e1 escassez de dados e de valida\u00e7\u00e3o de ferramentas progn\u00f3sticas.  Objetivo: Investigar e definir o perfil cl\u00ednico, laboratorial e ecocardiogr\u00e1fico de pacientes com IT grave a partir de vari\u00e1veis coletadas por meio do treinamento de um modelo de intelig\u00eancia artificial (IA).  M\u00e9todos: Estudo observacional, unic\u00eantrico, n\u00e3o intervencionista, de coorte retrospectiva, baseado em 71.911 laudos ecocardiogr\u00e1ficos realizados entre 2021 e 2024. Um modelo de processamento de linguagem natural (PLN) foi desenvolvido em Python para identificar casos de IT grave, extrair vari\u00e1veis e realizar o c\u00e1lculo automatizado dos escores TRI-SCORE e EuroSCORE II, posteriormente revisados. Considerou-se valor de p bicaudal &lt; 0,05 como estatisticamente significativo.  Resultados: Foram identificados 803 pacientes com IT grave. A m\u00e9dia de idade foi de 68,8 \u00b1 13,5 anos, e 64,1% eram mulheres. Hipertens\u00e3o arterial (71,7%) e fibrila\u00e7\u00e3o atrial (69,4%) foram as comorbidades mais prevalentes. A etiologia secund\u00e1ria predominou (96,8%), principalmente associada \u00e0 valvopatia mitral (68,5%). O risco cir\u00fargico foi elevado (medianas: EuroSCORE II = 13,4%; TRI-SCORE = 7). A mortalidade foi de 17,1%. Na an\u00e1lise secund\u00e1ria de mortalidade, a regress\u00e3o multivariada identificou preditores independentes, como TRI-SCORE em alto risco (relative risk [RR] 2,19; intervalo de confian\u00e7a de 95% [IC 95%] 1,14-4,21) e creatinina elevada (RR 3,13; IC 95% 1,91-5,14).  Conclus\u00f5es: Na maior casu\u00edstica brasileira de IT grave, constru\u00edda com aux\u00edlio de IA, a doen\u00e7a demonstrou elevada complexidade cl\u00ednica e progn\u00f3stica. A aplica\u00e7\u00e3o de PLN a grandes bases ecocardiogr\u00e1ficas mostrou-se eficiente, podendo subsidiar estudos multic\u00eantricos.<\/jats:p>","DOI":"10.36660\/abc.20250743","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:56:07Z","timestamp":1784649367000},"source":"Crossref","is-referenced-by-count":0,"title":["Aplica\u00e7\u00e3o da Intelig\u00eancia Artificial para Detec\u00e7\u00e3o, Caracteriza\u00e7\u00e3o e Estratifica\u00e7\u00e3o de Risco de Pacientes com Insufici\u00eancia Tric\u00faspide Grave"],"prefix":"10.36660","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6626-5157","authenticated-orcid":false,"given":"Luna Varela do","family":"Carmo","sequence":"first","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7180-5779","authenticated-orcid":false,"given":"Auristela Isabel de Oliveira","family":"Ramos","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8994-8345","authenticated-orcid":false,"given":"Dorival Julio Della","family":"Togna","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo da Silva","family":"Farias","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4903-5274","authenticated-orcid":false,"given":"Dimytri Alexandre de Alvim","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22636","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2022-002039","article-title":"Valvular Disease Burden in the Modern Era of Percutaneous and Surgical Interventions: The UK Biobank","volume":"9","author":"Tung M","year":"2022","journal-title":"Open Heart"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jcmg.2018.06.014","article-title":"Burden of Tricuspid Regurgitation in Patients Diagnosed in the Community Setting","volume":"12","author":"Topilsky Y","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0002-9149(98)01064-9","article-title":"Prevalence and Clinical Determinants of Mitral, Tricuspid, and Aortic Regurgitation (the Framingham Heart Study)","volume":"83","author":"Singh JP","year":"1999","journal-title":"Am J Cardiol"},{"issue":"9","key":"ref4","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1007\/s00595-007-3721-3","article-title":"Predictors of Secondary Tricuspid Regurgitation after Left-Sided Valve Replacement","volume":"38","author":"Wang G","year":"2008","journal-title":"Surg Today"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1161\/CIRCULATIONAHA.118.038946","article-title":"Excess Mortality Associated with Functional Tricuspid Regurgitation Complicating Heart Failure with Reduced Ejection Fraction","volume":"140","author":"Benfari G","year":"2019","journal-title":"Circulation"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.jcmg.2020.12.011","article-title":"Prognostic Implications of a Novel Algorithm to Grade Secondary Tricuspid Regurgitation","volume":"14","author":"Fortuni F","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"issue":"6","key":"ref7","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.pcad.2019.10.009","article-title":"Tricuspid Regurgitation is a Public Health Crisis","volume":"62","author":"Enriquez-Sarano M","year":"2019","journal-title":"Prog Cardiovasc Dis"},{"issue":"19","key":"ref8","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1136\/heartjnl-2019-315178","article-title":"Advanced Imaging of Right Ventricular Anatomy and Function","volume":"106","author":"Badano LP","year":"2020","journal-title":"Heart"},{"issue":"39","key":"ref9","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.1093\/eurheartj\/ehy352","article-title":"Development of Significant Tricuspid Regurgitation Over Time and Prognostic Implications: New Insights into Natural History","volume":"39","author":"Prihadi EA","year":"2018","journal-title":"Eur Heart J"},{"issue":"45","key":"ref10","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1093\/eurheartj\/ehaa643","article-title":"Isolated Tricuspid Valve Surgery: Impact of Aetiology and Clinical Presentation on Outcomes","volume":"41","author":"Dreyfus J","year":"2020","journal-title":"Eur Heart J"},{"issue":"39","key":"ref11","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1093\/eurheartj\/ehy434","article-title":"Clinical Presentation and Outcome of Tricuspid Regurgitation in Patients with Systolic Dysfunction","volume":"39","author":"Topilsky Y","year":"2018","journal-title":"Eur Heart J"},{"issue":"7","key":"ref12","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1093\/eurheartj\/ehab679","article-title":"TRI-SCORE: A New Risk Score for in-Hospital Mortality Prediction after Isolated Tricuspid Valve Surgery","volume":"43","author":"Dreyfus J","year":"2022","journal-title":"Eur Heart J"},{"issue":"45","key":"ref13","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1093\/eurheartj\/ehx381","article-title":"Staging Classification of Aortic Stenosis Based on the Extent of Cardiac Damage","volume":"38","author":"G\u00e9n\u00e9reux P","year":"2017","journal-title":"Eur Heart J"},{"issue":"7","key":"ref14","article-title":"Tricuspid Regurgitation and Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis","volume":"120","author":"Erbano BO","year":"2023","journal-title":"Arq Bras Cardiol"},{"issue":"10","key":"ref15","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1007\/s00392-023-02246-9","article-title":"TRI-SCORE is Superior to EuroSCORE II and STS-Score in Mortality Prediction Following Transcatheter Edge-to-Edge Tricuspid Valve Repair","volume":"112","author":"Gr\u00f6ger M","year":"2023","journal-title":"Clin Res Cardiol"},{"issue":"2","key":"ref16","article-title":"Clinical Outcomes and Progression Rate of Tricuspid Regurgitation in Patients with Rheumatic Mitral Valve Disease","volume":"10","author":"Caldas MMC","year":"2023","journal-title":"Open Heart"},{"key":"ref17","series-title":"spaCy: Industrial-Strength Natural Language Processing in Python [Internet]","author":"Honnibal M","year":"2020"},{"issue":"20","key":"ref18","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1056\/NEJMoa2300525","article-title":"Transcatheter Repair for Patients with Tricuspid Regurgitation","volume":"388","author":"Sorajja P","year":"2023","journal-title":"N Engl J Med"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.jacc.2024.10.067","article-title":"Quality of Life after Transcatheter Tricuspid Valve Replacement: 1-Year Results from TRISCEND II Pivotal Trial","volume":"85","author":"Arnold SV","year":"2025","journal-title":"J Am Coll Cardiol"},{"issue":"8","key":"ref20","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1093\/eurheartj\/ehad585","article-title":"TRI-SCORE and Benefit of Intervention in Patients with Severe Tricuspid Regurgitation","volume":"45","author":"Dreyfus J","year":"2024","journal-title":"Eur Heart J"},{"issue":"21","key":"ref21","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1016\/j.jacc.2015.04.011","article-title":"Functional Tricuspid Regurgitation: A Need to Revise Our Understanding","volume":"65","author":"Dreyfus GD","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"ref22","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jcin.2022.01.280","article-title":"Transcatheter Tricuspid Valve Replacement with the EVOQUE System: 1-Year Outcomes of a Multicenter, First-in-Human Experience","volume":"15","author":"Webb JG","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"issue":"16","key":"ref23","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1136\/heartjnl-2019-314741","article-title":"Characteristics and Treatment Strategies for Severe Tricuspid Regurgitation","volume":"105","author":"Ingraham BS","year":"2019","journal-title":"Heart"},{"issue":"43","key":"ref24","doi-asserted-by":"crossref","first-page":"4508","DOI":"10.1093\/eurheartj\/ehad653","article-title":"Tricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints","volume":"44","author":"Hahn RT","year":"2023","journal-title":"Eur Heart J"},{"issue":"44","key":"ref25","doi-asserted-by":"crossref","first-page":"4635","DOI":"10.1093\/eurheartj\/ehaf194","article-title":"2025 ESC\/EACTS Guidelines for the Management of Valvular Heart Disease","volume":"46","author":"Praz F","year":"2025","journal-title":"Eur Heart J"},{"issue":"2","key":"ref26","doi-asserted-by":"crossref","first-page":"100130","DOI":"10.1016\/j.shj.2022.100130","article-title":"Clinical Predictors of Mortality and Heart Failure Hospitalization in Patients with Severe Tricuspid Regurgitation","volume":"7","author":"Kumar K","year":"2022","journal-title":"Struct Heart"},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.athoracsur.2024.04.014","article-title":"Outcomes of Isolated Tricuspid Valve Surgery: A Society of Thoracic Surgeons Analysis and Risk Model","volume":"118","author":"Thourani VH","year":"2024","journal-title":"Ann Thorac Surg"},{"issue":"14","key":"ref28","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.039989","article-title":"Association of Diuretic Dosage with Outcomes in Patients with Hemodynamically Significant Isolated Tricuspid Valve Regurgitation","volume":"14","author":"Anand V","year":"2025","journal-title":"J Am Heart Assoc"},{"issue":"4","key":"ref29","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation: A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular Magnetic Resonance","volume":"30","author":"Zoghbi WA","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"issue":"3","key":"ref30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.echo.2025.01.006","article-title":"Guidelines for the Echocardiographic Assessment of the Right Heart in Adults and Special Considerations in Pulmonary Hypertension: Recommendations from the American Society of Echocardiography","volume":"38","author":"Mukherjee M","year":"2025","journal-title":"J Am Soc Echocardiogr"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/ehjci\/jev014","article-title":"Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"16","author":"Lang RM","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"}],"container-title":["Arquivos Brasileiros de Cardiologia"],"original-title":["Artificial Intelligence\u2013Driven Detection, Characterization, and Risk Stratification in Patients with Severe Tricuspid Regurgitation"],"link":[{"URL":"https:\/\/abccardiol.org\/wp-content\/uploads\/articles_xml\/0066-782x-abc-123-4-e20250743\/0066-782x-abc-123-4-e20250743.x98474.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:56:11Z","timestamp":1784649371000},"score":1,"resource":{"primary":{"URL":"https:\/\/abccardiol.org\/article\/aplicacao-da-inteligencia-artificial-para-deteccao-caracterizacao-e-estratificacao-de-risco-de-pacientes-com-insuficiencia-tricuspide-grave\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":31,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026]]}},"alternative-id":["S0066-782X2026000400609"],"URL":"https:\/\/doi.org\/10.36660\/abc.20250743","relation":{"is-translation-of":[{"id-type":"doi","id":"10.36660\/abc.20250743i","asserted-by":"subject"},{"id-type":"doi","id":"10.36660\/abc.20250743i","asserted-by":"object"}]},"ISSN":["1678-4170","0066-782X"],"issn-type":[{"value":"1678-4170","type":"electronic"},{"value":"0066-782X","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e20250743"}}