{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T18:07:28Z","timestamp":1784743648534,"version":"3.55.0"},"reference-count":18,"publisher":"Sociedade Brasileira de Cardiologia","issue":"5","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento: A doen\u00e7a de Chagas afeta milh\u00f5es de pessoas em todo o mundo e permanece como uma das principais causas de cardiomiopatia na Am\u00e9rica Latina. O diagn\u00f3stico precoce ainda representa um desafio em regi\u00f5es end\u00eamicas. A an\u00e1lise de eletrocardiografia (ECG) aprimorada por intelig\u00eancia artificial (IA) pode oferecer uma estrat\u00e9gia de baixo custo para rastreamento em larga escala em contextos com recursos limitados.  Objetivos: Avaliar o desempenho de um algoritmo de ECG aprimorada por IA combinado com dados cl\u00ednicos para a detec\u00e7\u00e3o da doen\u00e7a de Chagas em um programa de rastreamento comunit\u00e1rio realizado em uma regi\u00e3o altamente end\u00eamica do Nordeste do Brasil.  M\u00e9todos: Em agosto de 2024, 1.115 adultos foram submetidos \u00e0 aquisi\u00e7\u00e3o padronizada de ECG de 12 deriva\u00e7\u00f5es durante uma campanha de campo em Feira de Santana, Bahia, nordeste do Brasil. Um modelo de IA previamente treinado analisou os tra\u00e7ados de ECG e incorporou tr\u00eas vari\u00e1veis cl\u00ednicas: i) resid\u00eancia pr\u00e9via em \u00e1reas infestadas por triatom\u00edneos, ii) condi\u00e7\u00f5es habitacionais prec\u00e1rias e iii) hist\u00f3rico familiar de doen\u00e7a de Chagas. Indiv\u00edduos identificados como positivos pela IA foram classificados como casos suspeitos. Casos suspeitos e controles pareados (2:1) foram submetidos a testes sorol\u00f3gicos no ponto de cuidado.  Resultados: O algoritmo identificou 121 indiv\u00edduos (10,9%), correspondendo a uma preval\u00eancia estimada de doen\u00e7a de Chagas baseada em IA de 7,8% (intervalo de confian\u00e7a de 95% [IC95%]: 6,2-9,6). Entre os 112 indiv\u00edduos que completaram o teste sorol\u00f3gico, 13 apresentaram resultado positivo, todos pertencentes ao grupo suspeito positivo pela IA; nenhum caso soropositivo foi identificado entre os controles. A sensibilidade foi de 100% (IC95%: 69-100), a especificidade de 40% (IC95%: 30-50), o valor preditivo negativo de 100% (IC95%: 91-100) e o valor preditivo positivo de 12% (IC95%: 11-14), com uma raz\u00e3o de chances diagn\u00f3stica de 6,6.  Conclus\u00f5es: Um algoritmo de ECG aprimorada por IA combinado com vari\u00e1veis cl\u00ednicas simples demonstrou excelente sensibilidade para a detec\u00e7\u00e3o da doen\u00e7a de Chagas e pode representar uma ferramenta valiosa de triagem em contextos end\u00eamicos com recursos limitados.<\/jats:p>","DOI":"10.36660\/abc.20260032","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:17:22Z","timestamp":1784740642000},"source":"Crossref","is-referenced-by-count":0,"title":["An\u00e1lise de Eletrocardiografia Aprimorada por Intelig\u00eancia Artificial para o Diagn\u00f3stico da Doen\u00e7a de Chagas"],"prefix":"10.36660","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8450-4246","authenticated-orcid":false,"given":"Isabella Moreira Gonzalez","family":"Fonseca","sequence":"first","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil; Universidade Federal de Minas Gerais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8801-1828","authenticated-orcid":false,"given":"Maria Carmo Pereira","family":"Nunes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil; Universidade Federal de Minas Gerais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Sable","sequence":"additional","affiliation":[{"name":"Cardiovascular Outreach and Telemedicine Ochsner Children's Hospital,  EUA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1376-4694","authenticated-orcid":false,"given":"Renata Fonseca","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Hospital da Crian\u00e7a de Feira de Santana,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred Luciano Neves","family":"Santos","sequence":"additional","affiliation":[{"name":"Oswaldo Cruz,  Brasil; Funda\u00e7\u00e3o Oswaldo Cruz,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Rodrigues","family":"Gomes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2443-7047","authenticated-orcid":false,"given":"Adson Patrik Vieira","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo Fonseca","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Hospital da Crian\u00e7a de Feira de Santana,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noilson Lazaro","family":"Souza","sequence":"additional","affiliation":[{"name":"Oswaldo Cruz,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4693-9550","authenticated-orcid":false,"given":"Jos\u00e9 Augusto de Almeida","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clareci Silva","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del-Rei,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5586-774X","authenticated-orcid":false,"given":"Bruno Ramos","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brasil; Universidade Federal de Minas Gerais,  Brasil; Hospital Madre Teresa,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio L. 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