{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:18:36Z","timestamp":1787030316904,"version":"build-2736575974"},"reference-count":38,"publisher":"Sociedade Brasileira de Cardiologia","issue":"6","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento  O Brasil apresenta varia\u00e7\u00f5es regionais na mortalidade por cardiomiopatias, influenciada por caracter\u00edsticas demogr\u00e1ficas, desigualdades socioecon\u00f4micas e diferen\u00e7as no acesso aos servi\u00e7os de sa\u00fade. Entre 2001 e 2021, foram registrados 272.448 \u00f3bitos pela doen\u00e7a no pa\u00eds.  Objetivo  Analisar, em n\u00edvel nacional, o perfil epidemiol\u00f3gico e a distribui\u00e7\u00e3o t\u00eamporo-espacial da mortalidade por cardiomiopatias no Brasil, no per\u00edodo de 2001 a 2021.  M\u00e9todos  Estudo epidemiol\u00f3gico baseado em dados secund\u00e1rios do Sistema de Informa\u00e7\u00e3o sobre Mortalidade (SIM\/DATASUS) e estimativas populacionais do IBGE. Calcularam-se taxas brutas de mortalidade por munic\u00edpio. A an\u00e1lise temporal foi realizada pelo Joinpoint, estimando-se a varia\u00e7\u00e3o percentual anual (APC). A an\u00e1lise espacial utilizou o GeoDa, com suaviza\u00e7\u00e3o bayesiana e avalia\u00e7\u00e3o da autocorrela\u00e7\u00e3o espacial pelos \u00edndices de Moran Global e LISA. A signific\u00e2ncia estat\u00edstica foi estabelecida em p &lt; 0,05.  Resultados  Ocorreram 272.448 \u00f3bitos por cardiomiopatias, predominando em homens (58,65%), indiv\u00edduos com 80 anos ou mais (25,74%), brancos (52,18%), casados (36,77%) e com 1 a 3 anos de estudo completos (21,91%). A mortalidade m\u00e9dia foi de 6,66 por 100 mil habitantes, atingindo 7,64 por 100 mil em 2004 e caindo para 4,15 por 100 mil em 2020. Observou-se redu\u00e7\u00e3o anual significativa de 1,86% (p&lt;0,05). A an\u00e1lise espacial revelou aglomerados de alta mortalidade principalmente no Centro-Oeste, Sul e Sudeste, com destaque para Corumb\u00e1 de Goi\u00e1s (49,34\/100 mil).  Conclus\u00e3o  Houve redu\u00e7\u00e3o significativa da mortalidade por cardiomiopatias, embora persistam \u00e1reas cr\u00edticas que exigem estrat\u00e9gias direcionadas para vigil\u00e2ncia, diagn\u00f3stico precoce e manejo adequado.<\/jats:p>","DOI":"10.36660\/abc.20260064","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T17:25:14Z","timestamp":1785173114000},"source":"Crossref","is-referenced-by-count":2,"title":["An\u00e1lise T\u00eamporo-Espacial da Mortalidade por Cardiomiopatias no Brasil entre 2001 e 2021"],"prefix":"10.36660","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6546-9841","authenticated-orcid":false,"given":"Luiz Fernando","family":"Kubrusly","sequence":"first","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9233-4888","authenticated-orcid":false,"given":"Ana Clara Abdo","family":"Lopes","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5196-4426","authenticated-orcid":false,"given":"Fernanda Ritt de","family":"Souza","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5872-3867","authenticated-orcid":false,"given":"Gustavo Ferrucio","family":"Dieter","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2757-7862","authenticated-orcid":false,"given":"Laura","family":"Nadolny","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6644-6177","authenticated-orcid":false,"given":"Leonardo Moreira","family":"Dias","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1954-3994","authenticated-orcid":false,"given":"Let\u00edcia Moreira","family":"Dias","sequence":"additional","affiliation":[{"name":"Faculdade Pequeno Pr\u00edncipe,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6980-2159","authenticated-orcid":false,"given":"Luis Gustavo Machado","family":"Farias","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2114-9184","authenticated-orcid":false,"given":"Roberto Oliveira","family":"Basso","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9872-9120","authenticated-orcid":false,"given":"Vit\u00f3ria Naomi","family":"Okimura","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22636","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"14","key":"ref1","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/CIRCULATIONAHA.106.174287","article-title":"Contemporary Definitions and Classification of the Cardiomyopathies: An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention","volume":"113","author":"Maron BJ","year":"2006","journal-title":"Circulation"},{"issue":"6","key":"ref2","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrcardio.2016.25","article-title":"Epidemiology and Aetiology of Heart Failure","volume":"13","author":"Ziaeian B","year":"2016","journal-title":"Nat Rev Cardiol"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/eurheartj\/ehm342","article-title":"Classification of the Cardiomyopathies: A Position Statement from the European Society Of Cardiology Working Group on Myocardial and Pericardial Diseases","volume":"29","author":"Elliott P","year":"2008","journal-title":"Eur Heart J"},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.cardfail.2018.03.004","article-title":"Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline","volume":"24","author":"Hershberger RE","year":"2018","journal-title":"J Card Fail"},{"issue":"14","key":"ref5","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","article-title":"ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. 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Epidemiol"},{"issue":"2","key":"ref15","first-page":"152","article-title":"Cardiovascular Disease Mortality According to the Brazilian Information System on Mortality and the Global Burden of Disease Study Estimates in Brazil, 2000-2017","volume":"115","author":"Malta DC","year":"2020","journal-title":"Arq Bras Cardiol"},{"key":"ref16","doi-asserted-by":"crossref","DOI":"10.2196\/50653","article-title":"Prospective Spatiotemporal Cluster Detection Using SaTScan: Tutorial for Designing and Fine-Tuning a System to Detect Reportable Communicable Disease Outbreaks","volume":"10","author":"Levin-Rector A","year":"2024","journal-title":"JMIR Public Health Surveill"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-82212-1","article-title":"Comparative Evaluation of Spatiotemporal Methods for Effective Dengue Cluster Detection with a Case Study of National Surveillance Data in Thailand","volume":"14","author":"Rotejanaprasert C","year":"2024","journal-title":"Sci Rep"},{"key":"ref18","article-title":"From Infectious Diseases to Chronic Diseases: The Paradigm Shift of Spatial Epidemiology in Disease Prevention and Control","volume":"13","author":"Hu K","year":"2025","journal-title":"Front Public Health"},{"issue":"3","key":"ref19","article-title":"A Review of Bayesian Spatiotemporal Models in Spatial Epidemiology","volume":"13","author":"Wang Y","year":"2024","journal-title":"Int J Geo-Inf"},{"issue":"8","key":"ref20","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1161\/CIRCRESAHA.111.246876","article-title":"The Intersection between Aging and Cardiovascular Disease","volume":"110","author":"North BJ","year":"2012","journal-title":"Circ Res"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","DOI":"10.1186\/s12877-023-03880-8","article-title":"Marital Status and All-Cause Mortality Rate in Older Adults: A Population-Based Prospective Cohort Study","volume":"23","author":"Wang L","year":"2023","journal-title":"BMC Geriatr"},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000316","article-title":"Social Relationships and Mortality Risk: A Meta-Analytic Review","volume":"7","author":"Holt-Lunstad J","year":"2010","journal-title":"PLoS Med"},{"issue":"27","key":"ref23","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC)Developed with the Special Contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski P","year":"2016","journal-title":"Eur Heart J"},{"issue":"2","key":"ref24","first-page":"152","article-title":"Cardiovascular Disease Mortality According to the Brazilian Information System on Mortality and the Global Burden of Disease Study Estimates in Brazil, 2000-2017","volume":"115","author":"Malta DC","year":"2020","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"ref25","first-page":"46","article-title":"The COVID-19 Pandemic and Cardiovascular Disease in Brazil: Learning from the Data","volume":"119","author":"Cesena F","year":"2022","journal-title":"Arq Bras Cardiol"},{"issue":"4","key":"ref26","article-title":"Premature Mortality due to Non-Communicable Diseases and Deprivation in a Brazilian State Capital","volume":"31","author":"Cardoso LSM","year":"2026","journal-title":"Cien Saude Colet"},{"issue":"25","key":"ref27","first-page":"2982","article-title":"Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update from the GBD 2019 Study","volume":"76","author":"Roth GA","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"8","key":"ref28","first-page":"2973","article-title":"Noncommunicable Diseases, Risk Factors, and Protective Factors in Adults with and without HEALTH INSURANCE","volume":"25","author":"Malta DC","year":"2020","journal-title":"Cien Saude Colet"},{"issue":"9780","key":"ref29","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/S0140-6736(11)60202-X","article-title":"Successes and Failures in the Control of Infectious Diseases in Brazil: Social and Environmental Context, Policies, Interventions, and Research Needs","volume":"377","author":"Barreto ML","year":"2011","journal-title":"Lancet"},{"issue":"23","key":"ref30","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1056\/NEJMp1501140","article-title":"Brazil's Family Health Strategy--Delivering Community-Based Primary Care in a Universal Health System","volume":"372","author":"Macinko J","year":"2015","journal-title":"N Engl J Med"},{"issue":"2","key":"ref31","first-page":"161","article-title":"Epidemiology of Cardiovascular Diseases in Brazil: The Truth Hidden in the Numbers","volume":"115","author":"Polanczyk CA","year":"2020","journal-title":"Arq Bras Cardiol"},{"issue":"6","key":"ref32","first-page":"1725","article-title":"Infant Mortality Estimation in Brazil: What do Ministry of Health Data on Deaths and Live Births Say?","volume":"18","author":"Szwarcwald CL","year":"2002","journal-title":"Cad Saude Publica"},{"issue":"9723","key":"ref33","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/S0140-6736(10)60061-X","article-title":"Chagas Disease","volume":"375","author":"Rassi Jr A","year":"2010","journal-title":"Lancet"},{"key":"ref34","series-title":"Modern Epidemiology","author":"Rothman KJ","year":"2008","edition":"3rd"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1146\/annurev.pu.16.050195.000425","article-title":"Ecologic Studies in Epidemiology: Concepts, Principles, and Methods","volume":"16","author":"Morgenstern H","year":"1995","journal-title":"Annu Rev Public Health"},{"key":"ref36","doi-asserted-by":"crossref","DOI":"10.1186\/1478-7954-8-9","article-title":"Algorithms for Enhancing Public Health Utility of National Causes-of-Death Data","volume":"8","author":"Naghavi M","year":"2010","journal-title":"Popul Health Metr"},{"key":"ref37","series-title":"Age Standardization of Rates: A New WHO Standard","author":"Ahmad OB","year":"2001"},{"issue":"2","key":"ref38","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1538-4632.1995.tb00338.x","article-title":"Local Indicators of Spatial Association-LISA","volume":"27","author":"Anselin L","year":"1995","journal-title":"Geogr Anal"}],"container-title":["Arquivos Brasileiros de Cardiologia"],"original-title":["Spatiotemporal Analysis of Mortality from Cardiomyopathies in Brazil between 2001 and 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