{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T19:15:59Z","timestamp":1788203759418,"version":"build-2803163510"},"reference-count":18,"publisher":"Sociedade Brasileira de Cardiologia","issue":"7","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Bras. Cardiol."],"abstract":"<jats:p>Resumo  Fundamento  Os dist\u00farbios hipertensivos da gesta\u00e7\u00e3o complicam 5%-10% das gesta\u00e7\u00f5es e s\u00e3o respons\u00e1veis por 23%-38% das mortes maternas na Rep\u00fablica Dominicana.  Objetivo  Identificar os fatores associados ao desenvolvimento da pr\u00e9-ecl\u00e2mpsia e avaliar sua rela\u00e7\u00e3o com a morbidade e mortalidade materna e perinatal.  M\u00e9todos  Este estudo multic\u00eantrico, prospectivo, observacional, transversal e anal\u00edtico incluiu 469 parturientes de 17 hospitais da Rep\u00fablica Dominicana durante um per\u00edodo de 30 dias. A signific\u00e2ncia estat\u00edstica foi estabelecida em p &lt; 0,05.  Resultados  A pr\u00e9-ecl\u00e2mpsia esteve significativamente associada \u00e0 hipertens\u00e3o cr\u00f4nica (44,15% vs 16,87%; odds ratio [OR], 3,91; intervalo de confian\u00e7a de 95% [IC95%], 2,51-6,09), \u00e0 pr\u00e9-ecl\u00e2mpsia pr\u00e9via (44,64% vs 18,60%; OR, 3,53; IC95%, 2,24-5,56) e ao hist\u00f3rico familiar de pr\u00e9-ecl\u00e2mpsia (42,0% vs 19,38%; OR, 3,01; IC95%, 1,96-4,62). A pr\u00e9-ecl\u00e2mpsia tamb\u00e9m esteve associada \u00e0 prematuridade (54,6% vs 33,4%; OR, 2,40; IC95%, 1,62-3,55), ao baixo peso ao nascer (37,6% vs 18,5%; OR, 2,65; IC95%, 1,73-4,07) e ao descolamento prematuro de placenta (5,0% vs 2,4%; OR, 2,14; IC95%, 0,81-5,62). A mortalidade materna e fetal n\u00e3o esteve significativamente associada \u00e0 pr\u00e9-ecl\u00e2mpsia. Na an\u00e1lise de regress\u00e3o log\u00edstica multivari\u00e1vel, hipertens\u00e3o cr\u00f4nica (OR ajustada [AOR], 3,64; IC95%, 2,25-5,88), hist\u00f3rico familiar de pr\u00e9-ecl\u00e2mpsia (AOR, 2,86; IC95%, 1,85-4,42) e obesidade pr\u00e9-gestacional (AOR, 2,26; IC95%, 1,52-3,36) emergiram como preditores independentes de pr\u00e9-ecl\u00e2mpsia (todos p &lt; 0,05).  Conclus\u00e3o  A pr\u00e9-ecl\u00e2mpsia est\u00e1 associada a um risco aumentado de desfechos maternos e neonatais adversos, particularmente prematuridade e baixo peso ao nascer.<\/jats:p>","DOI":"10.36660\/abc.20260474","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:56:35Z","timestamp":1788202595000},"source":"Crossref","is-referenced-by-count":0,"title":["Fatores de Risco Associados \u00e0 Pr\u00e9-Ecl\u00e2mpsia e Seu Impacto na Morbidade e Mortalidade Materna e Neonatal na Rep\u00fablica Dominicana"],"prefix":"10.36660","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1741-8298","authenticated-orcid":false,"given":"Patricia","family":"Severino","sequence":"first","affiliation":[{"name":"Hospital Dr Salvador B Gautier,  Rep\u00fablica Dominicana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulgencio","family":"Severino","sequence":"additional","affiliation":[{"name":"Hospital Dr Salvador B Gautier,  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