{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T06:23:30Z","timestamp":1682058210011},"reference-count":8,"publisher":"ALUNA","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>Aim: To study the species composition of microorganisms isolated from patients with otomycosis, and to control the sensitivity of isolated microorganisms to the most commonly used antifungal drugs. \nMaterials and methods: The main group of study was 132 patients with a preliminary diagnosis of Otomycosis was carried out in the period 2020-2022.To study the sensitivity of isolated microorganisms to antifungal drugs, the Himedia paper disk method (India) was used. \nResults: Analysis of studies showed that among 132 patients, fungal infection was found in 101 patients (76%), the cultural method \u2013 in 31 patients (23.5%); of them women \u2013 56 (42.4%), men \u2013 60 (45.5%) aged 16 to 76; children \u2013 16 (12.1%) aged 6 to 12 years. However, among all patients (n = 132) with otomycosis, fungal lesions of the outer ear prevail, which were detected in 85 (64.4%) patients, that is, fungal otitis was detected in 47 (35.6%). \nConclusions: The general structure of the species spectrum of etiologically significant pathogens of otomycosis: Candida spp. (78.0%) of the total spectrum of isolates. The sensitivity of isolated micromycetes to antifungal drugs varied in different fungal species and in different antifungal drugs.<\/jats:p>","DOI":"10.36740\/merkur202301106","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T11:49:51Z","timestamp":1679658591000},"page":"42-47","source":"Crossref","is-referenced-by-count":0,"title":["THE MICROBIOLOGICAL STRUCTURE OF OTOMYCOSIS: SENSITIVITY PROFILE OF AGENTS TO ANTIFUNGAL DRUGS"],"prefix":"10.36740","volume":"51","author":[{"given":"Vladyslav A.","family":"Smiianov","sequence":"first","affiliation":[{"name":"SUMY STATE UNIVERSITY, SUMY, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetiana V.","family":"Ivakhniuk","sequence":"additional","affiliation":[{"name":"SUMY STATE UNIVERSITY, SUMY, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inna O.","family":"Plakhtiienko","sequence":"additional","affiliation":[{"name":"SUMY STATE UNIVERSITY, SUMY, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yevhen V.","family":"Smiianov","sequence":"additional","affiliation":[{"name":"SUMY STATE UNIVERSITY, SUMY, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polina O.","family":"Hornostaieva","sequence":"additional","affiliation":[{"name":"SUMY STATE UNIVERSITY, SUMY, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. Kamali Sarwestani H., Daie R. Ghazvini, Hashemi S.J. et. al. Investigation of Etiologic Agents and Clinical Presentations of Otomycosis at a Tertiary Referral Center in Tehran, Iran. Iran J Public Health. 2019;48(2):331\u2013337.","DOI":"10.18502\/ijph.v48i2.832"},{"key":"ref1","unstructured":"2. Zachepylo S. V. Gribcovi zahvoryvannya vuha: osoblyvosti clinichnogo perebigu, diagnostiki ta licuvannya (oglyad literatury). Vestnik problem biologii I medycyny. 2016;19(126):22-26."},{"key":"ref2","unstructured":"3. Bezshapochnyy S., Podovzhnii O., Polianska V., et al. Opportunities and prospects of microbioilogical diagnosis of ENT mycosis (review). Georgian Medical News. 2020;11(308):36\u201343."},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"4. Yeo S. G. Bacteriology of chronic suppurative otitis media \u2013 a multicenter study. Acta Otolaryngologia. 2007;127(10):1062\u2013 1067.","DOI":"10.1080\/00016480601126978"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"5. Park M. K., Nam D. W., Byun J. Y. et. al. Differences in Antibiotic Resistance of MRSA Infections in Patients with Various Types of Otitis Media. J Int Adv Otol. 2018;14 (3): 459\u2013463.","DOI":"10.5152\/iao.2018.5374"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Vennewald I., Klemm E. Otomycosis: Diagnosis and treatment. Clinics in dermatology. 2010;28 (2):202\u2013211.","DOI":"10.1016\/j.clindermatol.2009.12.003"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. O\u2019Sullivan J.M., Jenkinson H.F., Cannon R.D. Adhesion of Candida albicans to oral streptococci is promoted by selective adsorption of salivary proteins to the streptococcal cell surface. Microbiology. 2000;146:41\u201346.","DOI":"10.1099\/00221287-146-1-41"},{"key":"ref7","unstructured":"8. Evchev F. D., Gavvsky V.V. Ots\u0456nka effektivnosti l\u0456kuvannya ailments for otomycosis with stasis of the okteniseptu. Odessa Medical Journal. 2009;1(111):59\u201361."}],"container-title":["Polski Merkuriusz Lekarski"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T11:07:48Z","timestamp":1681988868000},"score":1,"resource":{"primary":{"URL":"https:\/\/polskimerkuriuszlekarski.pl\/wp-content\/uploads\/library\/PolMerkurLek2023i1.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023]]},"published-print":{"date-parts":[[2023,2]]}},"URL":"https:\/\/doi.org\/10.36740\/merkur202301106","archive":["Internet Archive"],"relation":{},"ISSN":["1426-9686"],"issn-type":[{"value":"1426-9686","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]}}}