{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T22:11:07Z","timestamp":1755036667602,"version":"3.38.0"},"reference-count":22,"publisher":"ALUNA","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>Aim: This study aimed to evaluate the serum levels of key biomarkers, including parathyroid hormone (PTH), vitamin D3, calcium, phosphate, and renal function tests (RFTS), in patients with chronic renal failure over three years.\nMaterials and Methods: A cohort of 83 patients with chronic renal failure and 70 healthy controls were followed, with data collected at one, two, and three years.\nResults: Significant differences were observed in the levels of creatinine, urea, phosphate, calcium, vitamin D, and parathyroid hormone between patients and controls. the study found a progressive increase in phosphate and parathyroid hormone levels, alongside a decrease in calcium and vitamin D levels in patients over time. strong correlations were observed between these biomarkers, highlighting the complex interplay between mineral metabolism and renal function in chronic renal failure.\nConclusions: These findings confirm the need for integrated management strategies to address these biochemical disturbances and improve the life quality of patients with chronic renal failure.<\/jats:p>","DOI":"10.36740\/merkur202501106","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T13:23:15Z","timestamp":1741699395000},"page":"40-46","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of parathyroid hormone, vitamin D3, calcium, phosphate, and RFT in patients with chronic renal failure: A three-year follow-up study"],"prefix":"10.36740","volume":"53","author":[{"given":"Hamid K.","family":"Al-Tameemi","sequence":"first","affiliation":[{"name":"DEPARTMENT OF MEDICAL LABORATORY TECHNIQUES, COLLEGE OF MEDICAL AND HEALTH TECHNIQUES, BILAD ALRAFIDAIN UNIVERSITY, BAQUBAH, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noor","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"DEPARTMENT OF MEDICAL LABORATORY TECHNIQUES, TECHNICAL INSTITUTE, KUFA, AL-FURAT AL-AWSAT TECHNICAL UNIVERSITY, NAJAF, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina A.A.","family":"Abdullah","sequence":"additional","affiliation":[{"name":"DEPARTMENT OF SCIENCE, COLLEGE OF BASIC EDUCATION, UNIVERSITY OF DIYALA, BAQUBAH, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noor Nayyef","family":"Oddah","sequence":"additional","affiliation":[{"name":"DEPARTMENT OF MEDICAL LABORATORY TECHNIQUES, COLLEGE OF MEDICAL AND HEALTH TECHNIQUES, BILAD ALRAFIDAIN UNIVERSITY, BAQUBAH, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref0","unstructured":"1. 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PTH assays in dialysis patients: Practical considerations. Semin Dial. 2019;32(1):9-14. doi: 10.1111\/sdi.12743.","DOI":"10.1111\/sdi.12743"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. Alwan MA, Ismaiel SM. Serum Biochemical Evaluation of Patients with Chronic Renal Failure on Hemodialysis. Yemeni Journal of Medical and Health Research. 2024;13(1&2). doi: 10.47372\/yjmhr.2024(13).1.3.","DOI":"10.47372\/yjmhr.2024(13).1.3"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22 Alsarraf ZH, Saber NR. Evaluate the Fluctuation in the Level of PTH, and Assess the Relationship Between PTH and Some Biochemical Parameter in Chronic Kidney Disease Patients Undergoing Hemodialysis. 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