{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T11:07:09Z","timestamp":1783854429406,"version":"3.55.0"},"reference-count":21,"publisher":"ALUNA","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:p>Aim: The study evaluates the effectiveness of wearable biometric devices, geofencing systems, and artificial intelligence algorithms in improving the quality of life and autonomy of individuals with Prader-Willi syndrome. It analyses the impact of digital ecosystems on reducing caregiver burden and personalizing therapy through objective data analysis.\nMaterials and Methods: A systematic literature review was conducted in PubMed, Web of Science, and the Cochrane Library databases since 2019. Research focused on metabolic monitoring, the use of gamification and virtual reality in rehabilitation, and the implementation of smart home technologies for patients with rare genetic syndromes. Analysis indicates that data from wearable devices enables the detection of prodromal states, mitigating episodes of hyperphagia and aggression. Geofencing systems provide a safe environment for autonomous physical activity, improving cardiovascular fitness and reducing caregiver anxiety. Artificial intelligence algorithms, by personalizing the energy balance with a precision of 10 kilocalories, significantly optimize weight reduction.\nConclusions: The digital support ecosystem redefines the care paradigm for Prader-Willi syndrome. Replacing human supervision with autonomous algorithmic control promotes behavioural stabilization and allows for greater patient self-determination. This process increases biological safety and significantly reduces the burden on caregivers, forming the basis of modern, individualized therapy.<\/jats:p>","DOI":"10.36740\/merkur202603116","type":"journal-article","created":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T11:02:37Z","timestamp":1783854157000},"page":"362","source":"Crossref","is-referenced-by-count":0,"title":["Modern technological innovations in the management of Prader-Willi syndrome: From restrictive supervision to digital autonomy"],"prefix":"10.36740","volume":"54","author":[{"given":"Iga Maria","family":"Owczarek-Danowska","sequence":"first","affiliation":[{"name":"MEDICAL UNIVERSITY OF WARSAW, WARSAW, POLAND"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka Wiktoria","family":"Paluszek","sequence":"additional","affiliation":[{"name":"MEDICAL UNIVERSITY OF WARSAW, WARSAW, POLAND"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip","family":"Jasi\u0144ski","sequence":"additional","affiliation":[{"name":"MEDICAL UNIVERSITY OF WARSAW, WARSAW, POLAND"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Bieniak","sequence":"additional","affiliation":[{"name":"PRASKI HOSPITAL OF THE TRANSFIGURATION OF OUR LORD, WARSAW, POLAND"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Kubiaczyk","sequence":"additional","affiliation":[{"name":"L. 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