{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T04:11:17Z","timestamp":1747887077388,"version":"3.41.0"},"reference-count":0,"publisher":"ALUNA","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To study and analyze data on clinical and laboratory parameters of investigated children in 6 months after treatment and 6 months after Covid-19 vaccination. \nMaterials and Methods: A prospective clinical and laboratory examination of a children group (group 1) with identified Covid-19 (n=68) was carried out in comparison with a group (n=31)  of Covid-19 vaccinated children (group 2) after  6 months of observation. \nResults: The data of Anti-SARS-CoV-2-S1-RBD IgG, non-significant intergroup differences in levels were found (344.71 \u00b1 87.62 versus 315.67 \u00b1 74.91 BAU\/ml, p=0.11). Significant differences were found in the children group  who was  6 months after  Covid-19 treatment and the control group, as well as in the group before and 6 months after Covid-19 vaccination, in the following parameters: IL-2 (p6&lt;0.01; p7&lt;0.01, with a prevalence of 6 and 4 times, respectively); IL-4 (p6&lt;0.01; p7&lt;0.01with a prevalence of 6 and 4.6 times, respectively),  IL-10 (p6&lt;0.01; p7&lt;0.01 with a prevalence of 6 and 4.8 times, respectively), Procalcitonin (p6&lt;0.01; p7&lt;0.01, 18 times and 1.4 times respectively).\n \tConclusions: In our study, according to the data of multivariate linear regression analysis, the level of Anti-SARS-CoV-2-S1-RBD IgG is the dependent variable, and D-dimer, Na level, Total Cholesterol, LF, IL-6, IgG are the influencing factors which determine the COVID-19 anti-infective protection.<\/jats:p>","DOI":"10.36740\/wlek\/203895","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T11:21:43Z","timestamp":1747826503000},"page":"838-844","source":"Crossref","is-referenced-by-count":0,"title":["\u0421omprehensive approach to comparative characteristics of clinical and laboratory parameters of the study in children -  in 6 months after  covid-19 treatment and 6 months after Covid-19 vaccination"],"prefix":"10.36740","author":[{"given":"Olesya M.","family":"Horlenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khrystyna A.","family":"Hechko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lyubomyra B.","family":"Prylypko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mykhaylo M.","family":"Hechko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fedir V.","family":"Horlenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bohdan M.","family":"Galay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,4,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-203895-125384","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-203895-125384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T11:21:49Z","timestamp":1747826509000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/-omprehensive-approach-to-comparative-characteristics-of-clinical-and-laboratory,203895,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"alternative-id":["203895"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/203895","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]}}}