{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:25:16Z","timestamp":1755221116327,"version":"3.43.0"},"reference-count":0,"publisher":"ALUNA","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To analyze the features of antibacterial treatment in children hospitalized for community-acquired pneumonia and the potential influence of dysbiosis.\nMaterials and Methods: The work analyzed medical records of 51 children, aged 2 to 13 years, who were hospitalized with community-acquired pneumonia.\nClinical symptoms, severity of the course, structure and duration of basic treatment measures, their cost, and signs of dysbiosis were studied in the patients.\nResults: The average duration of hospital treatment for patients with community-acquired pneumonia was 13.3 \u00b1 0.62 days, with 28 cases lasting between\n14 and 30 days. Given the community-acquired nature of the infection, the initial use of cephalosporins was irrational and significantly increased the cost of\ntreatment. After one week, signs of intestinal swelling, increased peristalsis, and unstable defecation, assessed as gut dysbiosis, appeared. Some symptoms,\nsuch as irritation in the throat, persistent cough, difficulty clearing mucus, shortness of breath, wheezing, and others, were regarded as signs of respiratory\ndysbiosis. The use of probiotics was initiated.\nConclusions: The study established the irrational use of third- and fourth-generation cephalosporins as first-line antibacterial treatment. Symptoms of intestinal\ndiscomfort and manifestations of mucociliary respiratory tract dysfunction should be regarded as gut-lung axis phenomena of dysbiosis.<\/jats:p>","DOI":"10.36740\/wlek\/207348","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T08:49:23Z","timestamp":1754642963000},"page":"982-986","source":"Crossref","is-referenced-by-count":0,"title":["Rational treatment of mild to moderate community-acquired pneumonia in previously healthy children"],"prefix":"10.36740","author":[{"given":"Oleksandr H.","family":"Buriak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurii M.","family":"Nechytailo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,7,25]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-207348-127394","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-207348-127394","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T08:49:23Z","timestamp":1754642963000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Rational-treatment-of-mild-to-moderate-community-acquired-pneumonia-in-previously,207348,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"alternative-id":["207348"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/207348","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]}}}