{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:16:14Z","timestamp":1787494574331,"version":"build-2736575974"},"reference-count":0,"publisher":"ALUNA","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To evaluate the associations of lower extremity arterial calcification (LEAC) with clinical profile of peripheral artery disease (PAD) patients with concomitant\nstable coronary artery disease (SCAD).\nMaterials and Methods: The cross-sectional study enrolled and analyzed clinical and instrumental data from 110 lower extremity PAD (chronic limb-threatening\nischemia) patients (mean age [mean \u00b1 standard deviation] 71\u00b18 years; 77 [70 %] males and 33 [30 %] females) with concomitant SCAD, underwent\nendovascular treatment during the period 2021-2025. LEAC was evaluated by CT-angiography with the assessment of Agatson calcium score (CS). The enrolled\nsample was subdivided into group 1 (CS &lt;1000 units [n=60]) and group 2 (CS \u22651000 units [very extensive LEAC; n=50]).\nResults: Group 2 (vs. group 1) was characterized by higher prevalence of atherosclerotic risk factors, namely smoking, overweight\/obesity, and the cases of\nfamily history of cardiovascular diseases. Hypertension and diabetes mellitus tended to be more prevalent in group 2, as opposed to group 1. In addition,\npatients with CS \u22651000 units (vs. &lt;1000) presented more frequently with atrial fibrillation\/flutter, heart failure stage C, previous acute cerebrovascular event\nand the most advanced Rutherford stage 6.\nConclusions: The PAD patients with concomitant SCAD and very extensive LEAC demonstrated more severe PAD and higher comorbidity burden, as compared to\ntheir counterparts with less calcified lower extremity arteries. The obtained data substantiate the integrated approach to be implemented in the management\nof such polyvascular patients, particularly by the use of LEAC as a potential predictor of adverse cardiovascular events.<\/jats:p>","DOI":"10.36740\/wlek\/207362","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T08:49:23Z","timestamp":1754642963000},"page":"1039-1046","source":"Crossref","is-referenced-by-count":3,"title":["Clinical correlates of lower extremity arterial calcification in peripheral artery disease patients with concomitant stable coronary artery disease"],"prefix":"10.36740","author":[{"given":"Sviatoslav Y.","family":"Denysov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuriy M.","family":"Hupalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasyl V.","family":"Lazoryshynets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22436","published-online":{"date-parts":[[2025,7,25]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-207362-127404","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-207362-127404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T08:49:25Z","timestamp":1754642965000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Clinical-correlates-of-lower-extremity-arterial-calcification-in-peripheral-artery,207362,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"alternative-id":["207362"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/207362","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]}}}