{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T10:40:11Z","timestamp":1756118411733,"version":"3.44.0"},"reference-count":0,"publisher":"ALUNA","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Aims: to assess condition of periodontal health and serum levels of interleukin-1\u03b2 in periodontitis and control groups and determine relationship between serum levels of interleukin-1\u03b2 and clinical periodontal parameters in periodontitis and control groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Materials and Methods: A sample consists of 80 male participants, ages thirty to sixty. A total of twenty people were separated into four groups: twenty people with stage I, twenty people with stage II, and twenty people with stage III periodontitis. Periodontium of control group was clinically sound, for every subject, clinical periodontal parameter were measured, such as depth of probing pocket, bleeding on probing, clinical attachment level, and plaque index. Following clinical evaluation, five milliliters of venous blood were extracted from each group. Serum samples were frozen at (-20)\u00b0C after centrifusion. Level of interleukin-1\u03b2 in serum was measured using mean of enzyme-linked immune-sorbent assay (ELISA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results: Group with stage III periodontitis had highest serum interleukin-1 \u03b2 levels, which were followed by those in stages II and I. There were notable variations between groups, with control group exhibiting lowest levels of interleukin-1 \u03b2 group. An increased stage of periodontitis was indicated by a statistical analysis of clinical periodontal parameters, which showed a significant difference in mean of all clinical periodontal parameters. There were non-significant weak positive correlations of interleukin-1\u03b2 with all clinical measures at all periodontitis groups, with exception of a moderately positive correlation with PLI, BOP, and CAL in stage I periodontitis group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Conclusion: Serum interleukin-1\u03b2 could be used to differentiate between periodontitis stages.<\/jats:p><\/jats:sec>","DOI":"10.36740\/wlek\/207379","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T09:59:06Z","timestamp":1756115946000},"page":"1327-1334","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of serum Interleukin-1\u03b2 and periodontal health status in patients with different stages of periodontitis"],"prefix":"10.36740","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4296-1516","authenticated-orcid":false,"given":"Nabaa Basim","family":"Alhusseini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6303-0569","authenticated-orcid":false,"given":"Maytham","family":"Adil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9350-1900","authenticated-orcid":false,"given":"Hussein Falah","family":"Fakhraldeen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,7,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-207379-128061","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-207379-128061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T09:59:11Z","timestamp":1756115951000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Assessment-of-serum-Interleukin-1-and-periodontal-health-status-in-patients-with,207379,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,30]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025]]}},"alternative-id":["207379"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/207379","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,30]]}}}